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In this paper, low-cost and two-cycle hardware structures of the PRINCE lightweight block cipher are presented. In the first structure, we proposed an area-constrained structure, and in the second structure, a high-speed implementation of the PRINCE cipher is presented. The substitution box (S-box) and the inverse of S-box (S-box−1) blocks are the most complex blocks in the PRINCE cipher. These blocks are designed by an efficient structure with low critical path delay. In the low-cost structure, the S-boxes and S-boxes−1 are shared between the round computations and the intermediate step of PRINCE cipher. Therefore, the proposed architecture is implemented based on the lowest number of computation resources. The two-cycle implementation of PRINCE cipher is designed by a processing element (PE), which is a general and reconfigurable element. This structure has a regular form with the minimum number of the control signal. Implementation results of the proposed structures in 180-nm CMOS technology and Virtex-4 and Virtex-6 FPGA families are achieved. The proposed structures, based on the results, have better critical path delay and throughput compared with other's related works.  相似文献   
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The central nervous system (CNS) is the most complex structure in the body, consisting of multiple cell types with distinct morphology and function. Development of the neuronal circuit and its function rely on a continuous crosstalk between neurons and non-neural cells. It has been widely accepted that extracellular vesicles (EVs), mainly exosomes, are effective entities responsible for intercellular CNS communication. They contain membrane and cytoplasmic proteins, lipids, non-coding RNAs, microRNAs and mRNAs. Their cargo modulates gene and protein expression in recipient cells. Several lines of evidence indicate that EVs play a role in modifying signal transduction with subsequent physiological changes in neurogenesis, gliogenesis, synaptogenesis and network circuit formation and activity, as well as synaptic pruning and myelination. Several studies demonstrate that neural and non-neural EVs play an important role in physiological and pathological neurodevelopment. The present review discusses the role of EVs in various neurodevelopmental disorders and the prospects of using EVs as disease biomarkers and therapeutics.  相似文献   
4.
BACKGROUND: Over the past several decades methyl tert‐butyl ether (MTBE) as additive to gasoline, intended to either boost ratings of fuel or to reduce air pollution, has been accepted worldwide. Since MTBE has high water solubility, the occurrence of fuel spills or leaks from underground storage tanks or transferring pipeline has led to the contamination of natural waters. In this study the degradation of aqueous MTBE at relatively high concentrations was investigated by a UV‐visible/ZnO/H2O2 photocatalytic process. The effects of important operational parameters such as pH, amount of H2O2, catalyst loading and irradiation time were also investigated. Concentration of MTBE and intermediates such as tert‐butyl formate and tert‐butyl alcohol were measured. RESULTS: Time required for complete degradation increased from 20 to 150 min when the initial concentration was increased from 10 to 500 mg L?1. The first‐order rate constants for degradation of MTBE were estimated to be 0.183–0.022 min?1 as the concentration increased from 10 to 500 mg L?1. Study of the overall mineralization monitored by total organic carbon analysis showed that at an initial concentration of 100 mg L?1 MTBE complete mineralization was obtained after 100 min under UV‐visible/ZnO/H2O2 photocatalysis. CONCLUSION: The data presented in this paper clearly indicated that UV‐visible/ZnO/O2 as an advanced oxidation process provides an efficient treatment alternative for the remediation of MTBE‐contaminated waters. Copyright © 2008 Society of Chemical Industry  相似文献   
5.
The peak flow of extraordinary large floods that occur during a period of systematic record is a controversial problem for flood frequency analysis (FFA) using traditional methods. The present study suggests that such floods be treated as historic flood data even though their historical period is unknown. In this paper, the extraordinary large flood peak was first identified using statistical outlier tests and normal probability plots. FFA was then applied with and without the extraordinary large floods. In this step, two goodness-of-fit tests including mean absolute relative deviation and mean squared relative deviation were used to identify the best-fit probability distributions. Next, the generalized extreme value (GEV), three-parameter lognormal (LN3), log-Pearson type III (LP3), and Wakeby (WAK) probability distributions were used to incorporate and adjust the extraordinary large floods with other systematic data. Finally, procedures with and without historical adjustment were compared for the extraordinary large floods in terms of goodness-of-fit and flood return-period quantiles. The results of this comparison indicate that historical adjustment from an operational perspective was more viable than without adjustment procedure. Furthermore, the results without adjustment were unreasonable (subject to over- and under-estimation) and produced physically unrealistic estimates that were not compatible with the study area. The proposed approach substantially improved the probability estimation of rare floods for efficient design of hydraulic structures, risk analysis, and floodplain management.  相似文献   
6.
This paper considers the problem of employing multiple unmanned aerial vehicles (UAVs) to the mobile ad hoc network (MANET) as relay backbone nodes to construct the backbone network, to improve the network connectivity, and to address many issues in the MANET such as linkage, capacity, load balance, and reliability. With considering the dynamic nature of the problem, this study provides several linear location problem models and their extensions to accommodate these issues. Due to the size of linear location models associated with a large number of constraints, the problem becomes computational challenging even with modest size of nodes. To overcome the computational barrier, we recast these location problem models using a quadratic unconstrained binary optimization (QUBO) framework and solve these QUBO models with a Tabu search heuristic with preprocessing. The analysis of the solutions that are produced by QUBO together with the comparisons made with the linear model highlight both the attractiveness and robustness of the proposed approach. The results of this study provide support to future advanced routing protocol development.  相似文献   
7.
In this paper a novel MEMS tunable CPW antenna with wide tuning range of frequency is presented. The antenna’s frequency tuning range increment is achieved by loading three novel large tuning range capacitors at radiation edge of antenna patch. Two techniques are employed for increasing the capacitors tuning range. First, dual gap technique is used to overcome the pull-in limitation and then two lateral beams are added in order to parallel movement of capacitive plate which increases the capacitance value. The simulation result shows that the resonance frequency tuning range of antenna increased from 1.96 GHz loaded by traditional capacitor to 6.89 GHz using the new capacitor structure. Also in resonance frequency, the antenna has a good impedance matching with transmission line even in high capacitance values.  相似文献   
8.
In this paper, we have fabricated a new microphone using aluminum (Al) slotted perforated diaphragm and back plate electrode, and photoresist (AZ1500) sacrificial layer on silicon wafer. The novelty of this method relies on aluminum diaphragm includes some slots to reduce the effect of residual stress and stiffness of diaphragm for increasing the microphone sensitivity. The acoustic holes are made on diaphragm to reduce the air damping, and avoid the disadvantages of non standard silicon processing for making back chamber and holes in back plate, which are more complex and expensive. Photoresist sacrificial layer is easy to deposition by spin coater and also easy to release by acetone. Moreover, acetone has a high selectivity to resist compared to silicon oxide and Al, thus it completely removes sacrificial resist without incurring significant damage silicon oxide and Al. The measured zero bias capacitance is 17.5 pF, and its pull-in voltage is 25 V. The microphone has been tested with external amplifier and speaker, the external amplifier was able to detect the sound waves from microphone on speaker and oscilloscope. The maximum amplitude of output speech signal of amplifier is 45 mV, and the maximum output of MEMS microphone is 1.125 μV.  相似文献   
9.
The main purpose of this paper is to provide a methodology for discussing the fuzzy. Bayesian system reliability from the fuzzy component reliabilities, actually we discuss on the Fuzzy Bayesian system reliability assessment based on Pascal distribution, because the data sometimes cannot be measured and recorded precisely. In order to apply the Bayesian approach, the fuzzy parameters are assumed as fuzzy random variables with fuzzy prior distributions. The (conventional) Bayes estimation method will be used to create the fuzzy Bayes point estimator of system reliability by invoking the well-known theorem called ‘Resolution Identity’ in fuzzy sets theory. On the other hand, we also provide the computational procedures to evaluate the membership degree of any given Bayes point estimate of system reliability. In order to achieve this purpose, we transform the original problem into a nonlinear programming problem. This nonlinear programming problem is then divided into four sub-problems for the purpose of simplifying computation. Finally, the sub problems can be solved by using any commercial optimizers, e.g. GAMS or LINGO.  相似文献   
10.
In this paper, a novel single-chip MEMS capacitive microphone is presented. The novelties of the method relies on the moveable aluminum (Al) diaphragm positioned over the backplate electrode, where the diaphragm includes a plurality of holes to allow the air in the gap between the electrode and the diaphragm to escape and thus reducing acoustical damping in the microphone. Spin-on-glass (SOG) was used as a sacrificial and isolating layer. Backplate is monocrystalline silicon wafer, that it is more stiff. This work will focus on design, simulation, fabrication and characterization of the microphone. The structure has a diaphragm thickness of 3 μm, a diaphragm size of 0.5 mm × 0.5 mm, and an air gap of 1.0 μm. The results show that the pull-in voltage is 105 V, the initial stress of evaporated aluminum diaphragm is around 1500 MPa and the zero bias capacitance of microphone is 2.12 pF. Comparing with the previous works, this microphone has several advantages: the holes have been made on diaphragm, therefore no need of KOH etching to make back chamber, in this way the chip size of each microphone is reduced. The fabrication process uses minimal number of layers and masks to reduce the fabrication cost.  相似文献   
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