全文获取类型
收费全文 | 2594篇 |
免费 | 180篇 |
国内免费 | 47篇 |
学科分类
医药卫生 | 2821篇 |
出版年
2022年 | 38篇 |
2021年 | 39篇 |
2020年 | 31篇 |
2019年 | 25篇 |
2018年 | 41篇 |
2017年 | 30篇 |
2016年 | 29篇 |
2015年 | 51篇 |
2014年 | 70篇 |
2013年 | 99篇 |
2012年 | 113篇 |
2011年 | 126篇 |
2010年 | 107篇 |
2009年 | 129篇 |
2008年 | 92篇 |
2007年 | 108篇 |
2006年 | 108篇 |
2005年 | 86篇 |
2004年 | 74篇 |
2003年 | 67篇 |
2002年 | 57篇 |
2001年 | 51篇 |
2000年 | 37篇 |
1999年 | 34篇 |
1998年 | 83篇 |
1997年 | 79篇 |
1996年 | 75篇 |
1995年 | 67篇 |
1994年 | 41篇 |
1993年 | 51篇 |
1992年 | 23篇 |
1991年 | 29篇 |
1990年 | 23篇 |
1989年 | 41篇 |
1988年 | 53篇 |
1987年 | 50篇 |
1986年 | 35篇 |
1985年 | 41篇 |
1984年 | 23篇 |
1983年 | 30篇 |
1982年 | 18篇 |
1980年 | 16篇 |
1976年 | 18篇 |
1963年 | 17篇 |
1959年 | 22篇 |
1958年 | 29篇 |
1957年 | 19篇 |
1956年 | 30篇 |
1955年 | 42篇 |
1954年 | 35篇 |
排序方式: 共有2821条查询结果,搜索用时 93 毫秒
2.
Dr. Arni Raghavendrarao Raghuram M.Ch. Subbiah Kumar MD Kathamuthu Balamurugan DA Arulmurugan DA Ramiah Krishnan M.Ch. Perichiappan Sivakami BS Eluvathingal Varghese John M.Ch. 《Indian Journal of Thoracic and Cardiovascular Surgery》2006,22(3):178-181
Background Beating heart surgery has now become the commonest technique of doing Coronary Artery Bypass Graft Surgery (CABG) in our country.
It is being used even in such high risk situations like diffuse coronary disease and Critical Left Main stem Stenosis (LMCS)
with good results. The aim of this study is to retrospectively review our results in Off-Pump Coronary Artery Bypass Surgery
(OPCAB) in patients with critical left main stem stenosis.
Methods This study is a retrospective analysis of the data of patients who underwent primary coronary artery bypass surgery. During
the period from April 2003 to September 2005 a total of 64 patients underwent OPCAB procedure for critical LMCS. During the
same period 10 patients underwent CABG on Cardio Pulmonary Bypass (CPB). The age range was 36–77yrs. The sex distribution
was M: F 53∶10. Ten patients were done as emergency. 2 of them were on Intra Aortic Balloon Pump (IABP) support preoperatively.
10 patients were high risk with a Euro score of ≥5.
Results Left Internal Mammary Artery (LIMA) was used in 78% of cases. Average grafts per patient was 2.96. The median ventilation
time was 5.91 hrs. New IABP insertion in postoperative period was required in 1 patient. One patient was reexplored for bleeding.
There was one perioperative myocardial infarction. 57% of patients did not need any blood transfusion. There was no conversion
to CPB. There was no operative mortality. Inotropes were used in ten cases.
Conclusions OPCAB is a safe method of revascularization in patients with critical LMCS. Preoperative IABP is useful in patients with cardiogenic
shock. However, there is a place for CPB in patients needing additional procedures like Mitral Valve repair (MV repair) or
Dor's procedure or when the vessels are very diffusely diseased. Those patients who are unstable despite IABP support may
be managed by Beating heart On Pump (BHOP) technique. 相似文献
3.
4.
5.
6.
7.
Diana H. Yu BA ; Kimberly A. Mace PhD ; Scott L. Hansen MD ; Nancy Boudreau PhD ; David M. Young MD 《Wound repair and regeneration》2007,15(5):628-635
Insulin-like growth factor-1 (Igf-1), a critical mediator of tissue repair, is significantly decreased in diabetic wounds. Furthermore, decreased levels of hypoxia-inducible factor 1-alpha (Hif-1alpha) and its target genes are also associated with impaired wound healing in diabetic mice. The aim of our study was to examine whether the reduced levels of Igf-1 are responsible for the reduction in Hif-1alpha protein synthesis and activity in diabetic wounds. We provide evidence that Igf-1 regulates Hif-1alpha protein synthesis and activity during wound repair. In addition, Igf-1 stimulated phosphytidylinositol 3-kinase activity in diabetic fibroblasts, which, in turn, increased activation of the translational regulatory protein, p70 S6 kinase. Moreover, improved healing of diabetic wounds by addition of recombinant IGF-1 protein was associated with an increase in Hif-1alpha protein synthesis and function in vivo. 相似文献
8.
9.
Boudreau FG 《American journal of public health and the nation's health》1941,31(9):967-968
10.
氟西汀与阿米替林治疗105例抑郁障碍病人的双盲对照试验 总被引:6,自引:4,他引:2
目的:评价国产氟西汀的抗抑郁作用及安全性。方法:采用随机、双盲对照、多中心研究,分为国产氟西汀组57例(男性22例,女性35例;年龄40±s13a),口服氟西汀20mg,qd,阿米替林57例(男性27例,女性30例;年龄40±14a),口服阿米替林75mg,bid,疗程6wk。结果:氟西汀治疗抑郁障碍的疗效与阿米替林相当,总有效率分别为85%及92%(P>0.05);氟西汀组的主要副作用有口干、便秘、恶心、心动过速等,但较之阿米替林程度轻且发生率低。结论:氟西汀的抗抑郁作用与阿米替林相当,副作用少,服用方便。 相似文献