CD3+木瓜提取物对ApoE基因缺陷小鼠血脂及炎性相关因素的影响

目的观察木瓜提取物对ApoE基因缺陷小鼠血脂水平、主动脉窦斑块中巨噬细胞活化及肿瘤坏死因子(TNF-α)水平的影响。方法30只雄性ApoE基因缺陷小鼠随机分为3组:对照组、低剂量组和高剂量组,低剂量组和高剂量组分别在基础饲料上添加5%和10%的木瓜提取物喷雾干燥颗粒,饲养16周后经小鼠眼眶静脉取血后处死动物,酶法测定血脂水平、采用免疫组化分析主动脉窦斑块中TNF-α的表达水平和采用免疫荧光反映斑块CD68阳性表达水平与巨噬细胞阳性表达率。结果低剂量组和高剂量组的血清TC和LDL-C显著低于对照组(P<0.05),木瓜提取物能显著下调斑块中TNF-α的表达水平以及减少巨噬细胞的阳性率。结论木瓜提取物降低了血清脂蛋白胆固醇水平(TC和LDL-C),减少了炎性因子TNF-α表达以及减弱巨噬细胞参与程度,预示其可能具有减缓动脉斑块发生发展的抗动脉粥样硬化作用。     

减肥塑身：七天七色水果减肥法

周一：木瓜 黄色水果 周一，带着一份红色的激情，开始一天的工作，我一定会精力充沛!今晚，我不会亏待自己。忙碌了一整天，哪里颐得上补充什么营养啊，就做一杯“橙色心情”吧。据说郑秀文、林熙蕾、徐怀钰等众多美女明星都是通过食用木瓜来丰胸和减肥的。[第一段]     

酸奶丰胸 30天纤体突围秀“S”

美丽的胸部总能让你风情万种,而不够丰满、挺拔的胸部会让你整体魅力指数直线下降。如何快速拥有S形好身材,《瘦佳人》在这里告诉你30天丰胸的酸奶神奇秘方。报料酸奶,瘦身丰胸好东东它含有大量活性乳酸菌,能有效地调节体内菌群平衡,促进胃肠蠕动,从而缓解便秘。还能制造较强的饱腹感,缓解迫切的食欲从而减少进餐量。     

皱皮木瓜总黄酮镇痛作用的机制分析

目的探讨皱皮木瓜总黄酮（FLC）的镇痛作用及其镇痛机制。方法利用小鼠热板、扭体法模型和兔耳皮下K^＋渗透外周致痛模型，观察FLC的镇痛作用，并分析与Ca^2＋的关系。结果FLC不仅具有全身镇痛作用，还具有外周镇痛作用；其全身及外周镇痛作用可被CaCl2拮抗，被EGTA所加强。5％，10％和20％FLC呈浓度依赖性抑制50mmol&#183;L^-1K^＋诱导蟾酥坐骨神经Ca^2＋含量增加；10％FLC抑制10^-5mmol&#183;L^-1NE诱导蟾酥坐骨神经Ca^2＋含量增加。结论FLC的镇痛作用机理可能与其抑制神经组织钙通道和非神经组织钙通道，减少致痛介质释放等因素有关。     

兴来愿得木瓜香

宋代名医许叔微在《本事方》中曾记载一则有趣的故事:安徽广德顾安中出外,偶然脚腿肿痛,不能行走,只好乘船回家。在船上,他将两脚搁在一包装货的袋上,下船时发现自己脚腿肿胀竟然已经减轻,疼痛减少,感到十分惊奇,就问船家袋中装的是何物?船家回答是木瓜。顾安中回家后于是就买来木瓜切片,装于袋中,每日将脚搁在上面,不久,他患的脚腿病就痊愈了。这一记载,说明了木瓜治疗风湿痹痛的神奇效验。木瓜在古代青年男女把它当作一种爱情的信物。《诗经》中有一首专门咏木瓜的诗:“投我以木瓜,报之以琼瑶。匪报也,永以为好也。”宋代苏东坡步其意借用…     

Sperm quality improvement after natural anti-oxidant treatment of asthenoteratospermic men with leukocytospermia

Aim： To study the immune-modulating and anti-oxidant effects of beta-glucan, papaya, lactoferrin, and vitamins C and E on sperm characteristics of patients with asthenoteratozoospermia associated with leucocytosis. Methods： Fifty-one patients referred to our Sterility Center for semen analysis were selected. Sperm parameters were assessed before and after patient＇s treatment with beta-glucan, lactoferrin, papaya, and vitamins C and E. DNA damage was assessed by the acridine orange test and sperm structural characteristics were evaluated by transmission electron microscopy. Results： After 90 days of treatment, an increase in the percentage of morphologically normal sperm （17.0 ± 5.2 vs. 29.8 ± 6.5） and total progressive motility （19.0± 7.8 vs. 34.8 ± 6.8） were detected. Structural sperm characteristics as well as chromatin integrity were also improved after treatment. In terms of leukocyte concentration in seminal fluid, a significant reduction was recorded （2.2 ± 0.9 vs. 0.9± 0.2）. Conclusion： The treatment of an inflammatory process by the synergic action of immune modulators and anti-oxidants could protect sperm during maturation and migration, leading to improved sperm function. （Asian JAndrol 2008 Mar;. 10： 201-206）