吉林省出口玉米中^90Sr,^137Cs和减钾总β放射性水平

本文报道了吉林省出口玉米中放射性＾９０Ｓｒ，＾１３７Ｃｓ和减钾总β放射性，某值分别是０．０６±０．０４、０．１２±０．０８和１．３０±１．６５Ｂｑ·ｋｇ＾－１。为我省粮食出口的质量控制提供了重要资料。     

不同敷料组合对烧伤患者供皮区创面微环境的影响

Objective To investigate the effect of dressing materials in various combinations on bum wound microenvironment and healing condition. Methods Two hundred donor sites with wounds of 0.3 mm in depth in 186 burn patients, who needed skingrafting and admitted to our ward were enrolled in study, and they were divided into A ( with dressing composed of aiginate + cotton pad for donor area), B ( with dressing composed of vaseline gauze + cotton pad for donor area) , C (with dressing composed of algi-nate+ foam dressing for donor area), D ( with dressing composed of vaseline gauze + foam dressing for donor area) groups according to random table method. Effect of dressings on wound evaporation and pH value were observed. Bacterial colonization, degree of pain complained by patients after dressing change, and wound healing time in each group were compared. Results One hundred and eighty-four patients complied with the study, while 2 patients were excluded due to untimely falling-off of the dressing. Wound evaporaton in respectively, among them B group showed optimal effect of keeping humidity (P<0.01). Wound pH value in A, B, C, D groups was 7.22±0.06, 7.41±0.03, 7.05±0.03, 7.34±0.06, respectively, among them it was highest in B group. The positive rate of bacteria in D group was highest (22.4%), and lowest in C group (4.0%). Pain was lightest in C group (score was 0.98±0.12), and most serious in B group ( score was 8.14±0.82). The shortest wound healing time was seen in C group (6.7±0.8 d) , and longest in D group (15.6±3.5 d). Conclusions Application of various dressings on similar wounds can pro-duce different wound microenvironment, which is closely related to wound healing time. Compared with pH value, humidity is the more important factor for wound healing.     

不同敷料组合对烧伤患者供皮区创面微环境的影响

Objective To investigate the effect of dressing materials in various combinations on bum wound microenvironment and healing condition. Methods Two hundred donor sites with wounds of 0.3 mm in depth in 186 burn patients, who needed skingrafting and admitted to our ward were enrolled in study, and they were divided into A ( with dressing composed of aiginate + cotton pad for donor area), B ( with dressing composed of vaseline gauze + cotton pad for donor area) , C (with dressing composed of algi-nate+ foam dressing for donor area), D ( with dressing composed of vaseline gauze + foam dressing for donor area) groups according to random table method. Effect of dressings on wound evaporation and pH value were observed. Bacterial colonization, degree of pain complained by patients after dressing change, and wound healing time in each group were compared. Results One hundred and eighty-four patients complied with the study, while 2 patients were excluded due to untimely falling-off of the dressing. Wound evaporaton in respectively, among them B group showed optimal effect of keeping humidity (P<0.01). Wound pH value in A, B, C, D groups was 7.22±0.06, 7.41±0.03, 7.05±0.03, 7.34±0.06, respectively, among them it was highest in B group. The positive rate of bacteria in D group was highest (22.4%), and lowest in C group (4.0%). Pain was lightest in C group (score was 0.98±0.12), and most serious in B group ( score was 8.14±0.82). The shortest wound healing time was seen in C group (6.7±0.8 d) , and longest in D group (15.6±3.5 d). Conclusions Application of various dressings on similar wounds can pro-duce different wound microenvironment, which is closely related to wound healing time. Compared with pH value, humidity is the more important factor for wound healing.     

压力疗法联合硅酮气雾剂防治瘢痕疗效观察

深度烧伤或体表外伤后所致的瘢痕增生,目前尚缺乏理想的防治方法[1].虽然硅硐胶膜及压力疗法治疗瘢痕各有一定效果,但均欠满意.我院自2002年10月以来分别采用硅酮气雾剂、弹力套及硅酮气雾剂加弹力套治疗烧伤及外科手术后形成的增生性瘢痕180例,并对各组疗效进行了观察和比较,现总结如下.     

低剂量辐射对小鼠种植肿瘤及其放疗的影响

本文作者用低剂量辐射（Ｄ１）诱导的兴奋效应，探讨对小鼠种植肿瘤及其放疗的影响，结果证明：Ｄ１可降低种植肿瘤细胞的成瘤率（Ｐ＜０．０５），并抑制其生长速度（Ｐ＜０．０５）；荷瘤鼠局部放疗预先给予Ｄ１，可提高放疗效果；并进一步证明：上述改变可能与Ｄ１提高了淋巴细胞自发增殖能力，降低电离辐射诱发自由基，提高抗氧化酶活性和增加ＤＮＡ修复能力有关。     

低剂量辐射诱导肿瘤细胞动力学变化及对丝裂霉素抗肿瘤效应的影响

目的：在低剂量照射条件下，合并化疗，以观察肿瘤细胞动力学变化。方法：应用０．０５ＧｙＸ射线对荷瘤鼠全身照射，结果：发现肿瘤细胞摄入３Ｈ—ＴｄＲ能力降低，Ｃ０／Ｇ１期细胞百分数增加，Ｓ期细胞百分数下降，Ｇ２期出现阻滞现象，且与对照组比较差异有显著性。低剂量辐射可增强丝裂霉素的化疗效果，导致肿瘤组织生长明显受抑。结论：上述结果证明：低剂量辐射可以抑制肿瘤细胞ＤＮＡ合成，诱导肿瘤细胞动力学改变，间接证实这种效应可促使肿瘤细胞向着程序化细胞死亡方向转变。且上述效应均有利于丝裂霉素的抗肿瘤作用。     

早期负压封闭引流治疗深Ⅱ度烧伤创面的临床疗效评价

Objective To evaluate the clinical curative effect of applying vaccum sealing drainage (VSD) therapy in treating deep partial-thickness burn wound at the initial stage prospectively, and to provide the basis for its clinical application. Methods Twenty-two patients with about 10% TBSA burn of the lower limbs, and in which partial-thickness wound exceeded 1% TBSA in each limb, were admitted to our hospital within 3 hours after burn from May 2009 to March 2010. Wounds in each patient were divided into VSD treatment group (treated with VSD therapy) and control group (treated with 10 g/L silver sulfadia-zine cream) based on the principles of symmetry of location, identical deepness, and similarity in size etc. The amount of water evaporation, the swelling intensity, the status of bacterial colonization, the degree of pain, the healing time, and the quality of healing of wounds in 2 groups were observed and compared. Data were processed with t test and rank-sum test. Results The observation was completed in 21 patients. All of the wounds were treated within 4 hours post burn (PBH). The amount of water evaporation of the normal skin and burn wounds before dressing coverage in VSD treatment group was respectively close to that in control group (with t value respectively 1.310, - 0. 911, P values all above 0.05) ; the amount of water evaporation on the surface of dressing in VSD treatment group [(44. 3 ±3.9) mL·h-1·m-2] was less than that in control group [(66.1 ±6.4) mL · h-1· m-2, t = -11.39, P <0.01]. In VSD treatment group, the circumference of proximal thigh increased (3.48 ±0.35) and (2.51 ±0.21) cm on post burn day (PBD) 3 , 7 as compared with that on PBH 5 , which was respectively smaller than that [(8.02 ± 0.41) , (3. 99 ± 0. 32) cm] in control group (with t value respectively 4. 110, 3. 569, P values all below 0. 01). Positive bacteria' culture rate on PBD 10 of each group was respectively lower than that at admission (with Z value respectively -3.220, -3.870, P values all below 0. 01) , and there was no significant statistical difference between 2 groups at admission or on PBD 10 (with Z value respectively - 0. 894, 0.000, P values all above 0.05). The wound surface in VSD treatment group was weak acidic (pH value 7. 12 ±0.06) on PBD 10,and it was neutral (pH value 7.41 ±0. 13) in control group. The wound pain degree in control group on PBD 1,3,7 was respectively higher than that in VSD treatment group (with t value respectively - 16. 132, -21.230, -16.453, P values all below 0.01). There was no significant statistical difference between 2 groups in healing time of wounds (t =1. 186, P >0.05). The healing quality of wounds in VSD treatment group (100. 00% , 100. 00%) 2 or 3 months after burn was better than that in control group (19. 05% , 85. 71%) (with Z value respectively -11.638, -3. 870, P values all below 0.01). Conclusions Early application of VSD therapy cannot expedite the healing process of deep partial-thickness burn wounds, but it can improve the healing quality. It is one of the effective methods to deal with deep partial-thickness burn wounds, which is worthy of clinical attention and further research.     

亚侧耳碱溶性多糖蛋白的抗肿瘤作用

亚侧耳碱溶性多糖蛋白的抗肿瘤作用曹瑞敏赵忠伟叶菲苏士杰(白求恩医科大学基础医学院长春130021)1材料药物亚侧耳子实体由东北师范大学李茹光教授鉴定为Hohenbueheliaserotina(Schard.Fr.)Sing。动物BALB/C纯系小鼠18～22g。雌雄兼用。瘤株小鼠肉瘤S180、小鼠肝癌H22均由本校提供。2方法与结果2.1药物配制用85%乙醇浸提数次去掉小分子物质,然后用水浸提,最后用0.1mol/LNaOH浸提,将所得碱提物作成灭菌水溶液备用。2.2碱提物对小....     

低剂量辐射对荷瘤鼠肿瘤抑制及对机体的保护作用

1994年5月15日日本新闻报道,劳动省已初步判断福岛县核电站职工岛桥申之死于白血病是由于受到职业性照射的结果。该人从1979年11月到1980年9月从事管道检查工作共11个月,接受40mSv照射,超过劳动省制定的"劳灾认定目标值"即职业病认定界度:5mSv×作业年数。