慢性淋巴细胞性甲状腺炎患者血清TGA、TMA阳性标准探讨及其临床意义

用放射免疫法,对117例经病理确诊的五种甲状腺疾病患者及80例正常人作血清TGA、TMA测定。结果,慢性淋巴细胞性甲状腺炎组血清TGA、TMA滴度显著高于其他四种甲状腺疾病及正常对照组(P<0.0001)。结果提示:(1)TGA+TMA对CLT的诊断具有特异性:(2)阳性标准为TGA+TMA≥69％～≤105％;(3)强阳性标准为TGA+TMA≥106％,阳性提示CLT,强阳性高度提示CLT的诊断。     

慢性淋巴性甲状腺炎的抗甲状腺抗体的动态变化

对64例慢性淋巴性甲状腺炎患者的抗甲状腺抗体的动态变化进行前瞻性研究,随诊1～8年(平均4.3±1.7年),32例(50％)抗体滴度明显降低。抗体滴度降低与患者年龄、甲状腺肿大程度、甲状腺功能状态及手术均无显著关系,而与随诊时间是显著的正相关。     

聚氨酯漆包线漆料的研究

研制的三—(羟乙基)异氰脲酸酯(SHEIC)改性聚氨酯漆包线漆料,将杂环结构引入聚氨酯漆膜,使漆包线具有优良的电绝缘性能和较高的软化击穿温度,同时保留了聚氨酯漆膜直焊性好的特点。对异氰酸酯的封闭反应和解封反应,以及SHEIC改性聚氨酯漆膜的热性能作了研究。     

TMA、TGA及有关甲状腺激素RIA在桥本氏甲状腺炎中的应用价值

应用RIA检测95例桥本氏甲状腺炎患者血清中TMA和TGA滴度，结果显示95例HT患者TMA和TGA滴度均明显高于正常（P＜0.001）。提示TMA、TGARIA检测对HT具有诊断价值。同时联合检测血清中TSH、FT_3、FT_4和TT_3TT_4含量，结果显示95例HT患者表现甲状腺功能异常61例（占64.2%）。提示HT表现的甲状腺功能状态与甲状腺自身抗体有关。     

131I治疗Graves'病后发生甲低与TGA,TMA及TRAb的关系

目的：从甲状腺自身免疫方面探讨^131Ⅰ治疗甲亢的效果及甲低发生的因素。方法：选择^131Ⅰ治疗的88例Graves’病甲亢患者随访3年，分为第1组(TGA、TMA、TRAb均阳性)和第二组(TGA、TMA阴性，TRAb阳性)。采用x^2分析自身抗体水平与甲低发生的关系。结果：1组甲低发生率为31．4％，2组为3．8％，1组明显高于2组，差异有显著性。结论：TGA、TMA和TRAb水平与确定^131Ⅰ剂量及甲低的发生关系密切。认为TGA、TMA水平高的患者应酌情减少^131Ⅰ用量。     

Graves''''眼病131I治疗后突眼的转归与TRAb及TGA、TMA的关系

目的探讨^132I治疗Graves’病后突眼的转归与TRAb及TGA、TMA的关系，为临床治疗Graves’病后突眼提供理论参考。方法选择伴有突眼的Graves’病患者78例进行^132I治疗，在治疗后第3、6、12个月进行随访，检测其TRAb及TGA、TMA浓度。结果治疗前TRAb及TGA、TMA水平高者，治疗后眼病获得改善的可能性较大；而治疗前TRAb及TGA、TMA水甲低者，治疗后其活性变化不大，眼病的改善也不明显，差异有显著性。结论TRAb及TGA、TMA水平与突眼的发生和转归关系密切。     

Isocyanatoethyl Methacrylate Telomerization and Cotelomerization

This article describes the use of isocyanatoethyl methacrylate (IEM) as a monomer in telomerization and cotelomerization reactions. First, the selectivity of benzenethiol addition to the unsaturation of IEM is proven. Even with an equimolar amount of reactants, benzenethiol reacts almost selectively with the ethylenic double bonds. The radical telomerization of IEM and its cotelomerization with MMA, in the presence of benzenethiol, has been achieved and shows that control of molecular weight is possible. Finally, the addition of a phosphonated alcohol to these telomers, followed by ester cleavage reactions, leads selectively to families of mono or diphosphonate products. The study of the thermal properties of the cotelomers shows that the degradation starts at 180 °C on the isocyanate group of IEM, and then on the ester group of MMA, and the decomposition is complete at 450 °C. The introduction of the phosphonated ester group decreases the glass transition temperature of the cotelomers, but after hydrolysis these values increase.

     

Development of a strategic model for integrating complementary medicines into professional pharmacy practice

Background

Traditional medicine (TM) and complementary medicine (CM) products have played an increasingly important role in the business of pharmacy for over two decades in a number of countries. With a focus on the quality use of all medicines including complementary medicines, there have been a number of initiatives to encourage the integration of TM/CM products into professional practice. Recent studies report that many of the barriers that prevent such integration remain.