双膦酸盐对骨转移癌骨痛治疗及血清钙磷影响

Objective: Bisphosphonates were widely used with the rate of malignant tumor with bone metastases increasing rapidly. The aim of this study was to evaluate zoledronic acid and pamidronic acid on treating osteatgia of malignant tumor with bone metastases and serum calcium, phosphorus and alkaline phosphorus movement. Methods: One Hundred cancer patients with bone metastases were diagnosed according to pathological and imaging methods. After zoledronic acid or pamidronic acid intravenous infusion one and two months, ostealgia degree, serum calcium, serum phosphorus and alkaline phosphorus were observed before bisphosphonates treatment, one and two months after treatment, respectively. Results:Ostealgia degree did not change significantly after diphosphonates treatment from one to two months (P ＞ 0.05). The linear correlation between serum calcium and serum phosphorus on bone metastases cancer patients before therapy was dismissed after bisphosphonates treatment one month and did not recover in two months. The incidence of hypo-calcium after diphosphonate treatment one month (54%) and two months (56%) were significantly increased than that before treatment (36%) (x2 = 6.55, P = 0.011; x2 = 8.05, P = 0.005). Serum calcium and serum phosphorus were both decreased after treatment one month (t = 4.39, P = 0.000; t = 2.50, P = 0.014) and two months (t = 4.32, P = 0.000; t = 2.49, P = 0.010). There had no difference between zoledronic acid and pamidronic acid on treating of ostealgia and serum calcium and phosphorus changing.Conclusion: Zoledronic acid and pamidronic acid can relief ostealgia of cancer patients with bone metastases and inducehypo-calcium, break the linear relationship between calcium and phosphorus. There have no difference between zoledronic acid and pamidronic acid on treating ostealgia and inducing hypo-calcium and hypo-phosphorus.     

高能复合射孔可能引起的管内窜原因分析及预防措施

针对2口井上返试油时,封隔已试层采用电桥或电桥+投灰工艺,目的层采用一体式高能复合射孔技术进行复合射孔后,地层产液液性及产能与下部已封闭层接近情况,采用措施验证,均为管内窜通。分析了桥塞失封的主要原因,提出使用高能复合射孔技术时的转层封隔要求。通过实验井进行验证,提出的措施能够预防高能复合射孔造成管内窜情况的发生。     

复杂边界裂缝性低渗油藏有限元试井

建立了复杂外边界裂缝性低渗透油藏渗流数学模型,使用迦辽金法推导模型的有限元方程。考虑井筒存储和表皮效应的影响,将井壁视为内边界、外边界封闭或定压,或为同时含封闭和定压边界的混合边界;使用Delaunay三角形对求解区域剖分,时间采用隐式方式离散;编制程序求解有限元方程得到不同时间的油藏压力分布,绘制不同类型边界的地层中一口井及地层中不同位置一口井的试井理论曲线;分析了启动压力梯度、外边界及井位置对井底压力的影响。结果表明有限元法处理复杂外边界可以取得较好效果。     

Tertiary-treated municipal wastewater is a significant point source of antibiotic resistance genes into Duluth-Superior Harbor

In this study, the impact of tertiary-treated municipal wastewater on the quantity of several antibiotic resistance determinants in Duluth-Superior Harbor was investigated by collecting surface water and sediment samples from 13 locations in Duluth-Superior Harbor, the St. Louis River, and Lake Superior. Quantitative PCR (qPCR) was used to target three different genes encoding resistance to tetracycline (tet(A), tet(X), and tet(W)), the gene encoding the integrase of class 1 integrons (intI1), and total bacterial abundance (16S rRNA genes) as well as total and human fecal contamination levels (16S rRNA genes specific to the genus Bacteroides ). The quantities of tet(A), tet(X), tet(W), intI1, total Bacteroides , and human-specific Bacteroides were typically 20-fold higher in the tertiary-treated wastewater than in nearby surface water samples. In contrast, the quantities of these genes in the St. Louis River and Lake Superior were typically below detection. Analysis of sequences of tet(W) gene fragments from four different samples collected throughout the study site supported the conclusion that tertiary-treated municipal wastewater is a point source of resistance genes into Duluth-Superior Harbor. This study demonstrates that the discharge of exceptionally treated municipal wastewater can have a statistically significant effect on the quantities of antibiotic resistance genes in otherwise pristine surface waters.     

建筑用纺织材料的应用研究进展

总结纺织材料在建筑领域中的应用研究进展。通过介绍建筑用纺织材料的结构特点及优势,探讨了纤维增强复合材料、隔声隔热材料、帆布材料、膜结构材料、防水材料、防污自洁膜材和装饰用材料在建筑领域中的应用,指出建筑用纺织材料的发展潜力和开发策略是引进技术提高生产制造水平、有效利用新型天然纤维、开发智能建筑用纺织品,认为,传统建筑材料与纺织材料相互结合、共同促进是未来的发展趋势。     

铅酸蓄电池的BOM构建

本文针对铅酸蓄电池的结构以及制造工艺,较为详细地描述了BOM（物料清单）的构建方式。根据生产实际以及数据管理两方面的特点提出标准电池层,并且把建立该层次的各种物料详细加以分析,探讨了每一种物料的共性与特点,力求真正做到结合生产实际。     

基于IESNAg0．1标准的绿色照明设计

电气照明灯具是最早的用电设备之一,一直以来也是电能消耗的重要组成部分,约占到全球电能消耗的五分之一。以西部地区首个全国绿色建筑创新奖一等奖项目——后勤工程学院绿色建筑示范楼为例,结合具体工程设计措施,分析了GB50034与IESNA90．1标准中在照明功率密度值、光源及灯具的选择、照明控制等设计要点上的异同,对绿色照明实施过程中的IESNA标准可借鉴之处进行了重点阐述,并对GB50034的修订提出了建议。     

Ultra-fast PCR method for the distinguishing between Miichthys miiuy and Sciaenops ocellatus

Food Science and Biotechnology - The mi-iuy croaker Miichthys miiuy has immense commercial value in the Republic of Korea. The red drum Sciaenops ocellatus is widely produced by aquaculture,...     

氢核磁共振结合支持向量机鉴别蜂蜜植物源

目的建立基于氢核磁共振(1H nuclear magnetic resonance,1H NMR)结合支持向量机分类模型鉴别蜂蜜植物源的方法。方法采集荆条蜜、油菜蜜、洋槐蜜、葵花蜜4种不同植物源的蜂蜜共计122例样品的谱图信息,分全谱(δ0.10~δ9.50)、脂肪区(δ0.10~δ3.00)、糖类化合物区(δ3.00~δ6.00)、芳香区(δ6.00~δ9.50)4个不同积分区间建立分类模型,结合主成分权值系数筛选特征变量,进一步优化判别模型。结果基于主成分权值系数筛选变量范围δ3.40~δ3.90和δ4.60~δ4.70内共计267个积分变量,以该区域积分变量为输入变量建立的支持向量机分类模型,对训练集的判别正确率为97.53%,对测试集的判别正确率为100%。结论通过主成分权值系数能有效筛选特征变量,减少输入变量的同时提高模型稳健性与准确性,基于氢核磁共振结合支持向量机分类模型能有效鉴别不同植物源蜂蜜。     

炼油污泥处理工艺问题分析与对策

大庆分析了大庆石化公司炼油污泥处理工艺存在的问题及影响因素。采取多项技术改进措施,使炼油剩余污泥处理达到指标要求、外排泥饼含水率合格,各项排水水质指标均优于目标值。