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1.
目的 调查卒中亚急性期偏瘫患者出院后习得性废用发展情况,分析习得性废用与患者人口学因素、 临床特点及功能恢复的相关性。 方法 前瞻性连续纳入2018年7月-2019年12月期间南方医科大学深圳医院预备出院的卒中偏瘫患 者。收集患者一般资料和临床特点,并在出院后4周、8周和12周用运动活动记录表(motor activity log, MAL)评估患者的习得性废用情况,在出院前3 d,出院后4周、8周和12周用改良Ashworth指数测试肘 腕屈肌群肌张力,偏瘫上肢功能测试香港版、Fugl-Meyer评定量表上肢部分和箱块测试评价上肢功 能,功能独立性评定评价日常生活能力。对各随访时间点MAL与其他评估量表、人口学因素和临床特 点进行相关性分析。 结果 研究完成随访患者47例,男性36例(76.6%),平均年龄58.74±11.08岁,平均发病时间 48.00±28.38 d,其中缺血性卒中32例(68.1%),出血性卒中15例(31.9%)。MAL的患手使用频率/ 患者活动质量在出院后4周、8周和12周时分别为2.66(1.38~4.03)分/2.87(1.03~3.56)分、3.30 (1.93~4.41)分/3.17(1.55~3.77)分和3.59(2.00~4.33)分/3.28(2.00~3.96)分,除8周与12周 之间的患手使用频率差异无统计学意义之外,其他时间点之间差异均具有统计学意义。各随访时间 点患者肘屈肌群张力变化差异无统计学意义(P =0.076),其余功能表现均显著恢复(均P <0.05)。出 院后4周、8周和12周各时间点,MAL与年龄呈一般正相关(ρ=0.33~0.39),与发病时间呈一般负相关 (ρ=-0.49~-0.33),与肘腕部屈肌张力呈一般至中等负相关(ρ=-0.58~-0.38),与日常生活能力 呈一般至中等正相关(ρ=0.30~0.60),与上肢运动功能呈一般至强正相关(ρ=0.49~0.76)。 结论 卒中亚急性期偏瘫患者出院后患肢仍然可以保持显著的功能恢复,但依然面临习得性废用 的挑战,且习得性废用与年龄、发病时间、腕肘屈肌群张力、日常生活生活能力和上肢功能相关。  相似文献   

2.
Abstract

Background: Attainment of functional independence is the ultimate goal of a sound stroke rehabilitation program. Good trunk stability is essential for balance and extremity use. Stroke patients may have upper extremity impairments that may affect functional activity and lower extremity impairments that may hinder mobility. Hence, quantifying the specific levels of impairment in the trunk, upper extremity, and lower extremity is helpful to determine the extent to which each might influence the ability to perform activities of daily living. Objective: To assess the impairment of the trunk and the upper and lower extremity of stroke patients and correlate it with overall function. Methods: A cross-sectional repeated correlation study. Twenty-three subjects with a first-time stroke, between 50 and 75 years of age, of both genders, admitted in hospital within 5 weeks of stroke onset were included using purposive sampling technique. On the eighth day of the stroke, trunk impairment was assessed using the Trunk Impairment Scale, upper and lower limb impairment was assessed using the Simplified Stroke Rehabilitation Assessment of Movement (upper and lower limb subscale, respectively), and overall function was measured by FIM. Results: Trunk activity showed highly significant correlation (r = 0.598, P = .003) with overall function compared with upper limb activity (r = 0.501, P = .015). Lower limb impairment showed no correlation with overall function (r = 0.208, P = .342). Conclusions: The overall functional independence in acute stroke patients is most closely correlated with the levels of impairments of trunk function, followed by upper limb impairments.  相似文献   

3.
MethodsAIS patients with AF hospitalized within 7 days of onset were identified from a prospective nine-center stroke registry database. Two cohorts were defined: patients diagnosed with AF prior to the stroke event (admission cohort) and patients diagnosed with AF at discharge from hospital (discharge cohort). Any of the following conditions were regarded as nonadherence to guidelines in this study: use of anticoagulant or nonuse of antithrombotics with CHADS2 score=0, nonuse of antithrombotics with CHADS2 score=1, or nonuse of anticoagulant with CHADS2 score ≥2.ResultsOverall, 406 patients were enrolled in the admission cohort and 518 in the discharge cohort. The rates of nonadherence before a stroke event and at discharge were 77.8% and 33.3%, respectively. These rates varied widely for both cohorts, with interhospital differences being statistically significant. Multivariable analysis revealed that old age, stroke history, and congestive heart failure were associated with nonadherence before stroke. At discharge, males, coronary heart disease, inappropriate antithrombotic use before stroke, and functional disability at discharge were associated with nonadherence.ConclusionsThis study shows that antithrombotic use in AIS patients with AF might be not optimal before and after stroke in Korea.  相似文献   

4.
5.
Purpose: The primary focus of this review was to find out the effectiveness of robotics in improving upper extremity functions among people with neurological problems in the arena of physical rehabilitation.

Material and methods: Two reviewers independently scrutinized the included studies. The selected studies underwent quality assessment by Physiotherapy Evidence Database (PEDro) scale. Randomized Controlled Trial (RCT) having a score of four or more were included in the review. A search was conducted in PUBMED, MEDLINE, CINAHL, EMBASE, PROQUEST, science direct, Cochrane Library, PEDro and Google Scholar.

Results: A total of 202 studies were identified. After removal of duplication, inclusion and exclusion criteria’s n?=?23 studies were included in the review process. For analysis, only the primary outcome measures of the studies were taken into account. Studies finally included in analysis were n?=?21. The included studies were 19 in stroke, 1 in cerebral palsy (CP) and 1 study in multiple sclerosis (MS). No RCTs were reportedly found in spinal cord injury (SCI), Parkinson and motor neuron disease (MND).

Conclusions: Studies related to stroke showed a clear definiteness in the improvement of upper extremity functions. On the contrary, there still remains a need for quality trials in CP, MS to establish the efficacy of robotics in upper extremity rehabilitation.  相似文献   


6.
BackgroundStroke has been identified as an epidemic and an important cause of morbidity and mortality globally, and at least 85% of stroke survivors experience hemiplegia and upper-extremity function of at least 69% of patients are affected. Over 50% of stroke survivors have impairment of motor function of the upper extremity; therefore there is pertinent need to use functional rehabilitation approaches such as; mirror therapy and constraint induced movement therapy for stroke survivors to regain upper extremity motor function.AimsTo compare the efficacy of mirror therapy (MT) with constraint induced movement therapy (CIMT) on the upper extremity motor function and activities of daily living (ADL) in chronic stroke survivors.Methods30 stroke survivors were recruited for this study. They were randomized into three groups, the MT plus conventional therapy group, CIMT plus conventional therapy group and control group. Upper extremity motor function and ADL were assessed. Participants were assessed at baseline and after seven weeks of intervention.ResultsThe MT and CIMT groups’ intervention both had significant improvement on upper extremity motor function and ADL, however, there was no significant difference on upper motor function (p=0.503) and ADL (p=0.133) across the three groups.ConclusionThis study concluded that neither of MT nor CIMT had an additional significant improvement compared to conventional therapy alone on recovery of motor function in the upper extremity and performance of ADL.  相似文献   

7.
8.
Background: Orthoses for individuals with stroke is considered an integral part of the neurorehabilitation process. However, there are no universal guidelines to determine the initiation period, duration, or type of orthosis for stroke patients.

Objectives: For this study, we systematically reviewed the evidence surrounding the use of orthoses for stroke-related upper extremity deficits.

Methods: Medical librarians searched MEDLINE, EMBASE, CINAHL, Cochrane Database of Systematic Reviews, Cochrane Controlled Trials Register, Health Technology Assessment Database, Physiotherapy Evidence Database, and OTSeeker using subject headings and keywords related to upper extremities, orthoses, and stroke. The resulting articles were evaluated for inclusion by the systematic review team. Articles that met the inclusion criteria were appraised for content and quality using the “Evaluation Guidelines for Rating the Quality of an Intervention Study (EQIS).

Results: 14 studies were included, with the mean score of 31.29 (out of 48) for the EQIS using an ordinal scale with a range of 23–43.6 studies produced significant outcomes with effect sizes ranging from d = .52 (wrist flexion PROM) to d = 9.02 (patient satisfaction with orthosis).

Conclusion: Future studies should aim to utilize homogenous outcome measures while exploring variability in dosage and level of upper extremity impairment upon initiation. Additionally, universal guidelines for initiation period, duration, and type of orthosis for patients post-stroke need to be established.  相似文献   


9.
Background and Purpose: The purpose of this study was to review the methods used to analyze the kinematics of upper limbs (ULs) of healthy and poststroke adults, namely specificities of sampling and motor tasks.

Summary of review: A database of articles published in the last decade was compiled using the following search terms combinations: (“upper extremity” OR “upper limb” OR arm) AND (kinematics OR motion OR movement) AND (analysis OR assessment OR measurement). The articles included in this review (1) had the purpose to analyze objectively a three-dimension kinematics of ULs, (2) studied functional movements or activities of daily living (ADL) involving uppers limbs, and (3) studied healthy and/or poststroke adults. Fourteen articles were included (four studied a healthy sample, three analyzed poststroke patients, and seven examined both poststroke and healthy participants).

Conclusion: Most of the recommended demographic and stroke information, such as some preexisting conditions to stroke, initial stroke severity, and stroke location, were not collected by all or most of the articles. Time poststroke onset was presented in all articles but showed great variability. Few articles identified anthropometric characteristics and adjusted task environment to them. Most of the samples were composed mainly by males and had a low mean age, which does not represent poststroke population. Most articles analyzed “functional movements”, namely simulations of ADL.

Implication of key findings: Future research should identify the recommended information to allow an adequate stratification. Acute phase after stroke, real ADL with different complexities, and ipsilesional UL should be studied.  相似文献   


10.
Background: Stroke can result in pain and loss of motor control in the hemiplegic shoulder, and while prevention of secondary changes is likely to be the most effective management, there is limited evidence directing clinicians towards the most at-risk patients.

Objectives: The aim of this case series was to investigate the presentation of shoulder pain, motor impairment, shoulder passive range of motion (PROM) and alignment of the hemiplegic shoulder following acute stroke.

Methods: This study reported data that was collected as part of a pilot randomized controlled trial investigating kinesiology taping of the hemiplegic shoulder. Participants with a diagnosis of acute stroke and severe upper limb motor impairment were included. From 24-h post stroke and continuing every three days until discharge, measurements of shoulder pain (visual analogue scale, Ritchie Articular Index), motor impairment (Chedoke McMaster Stroke Assessment), PROM and alignment (both clinical measures) were collected. Clinical trial registry number – ACTRN12615000502538.

Results: Of 156 patients screened over six months, 10 of 15 eligible participants were recruited. On initial assessment, three participants reported pain and all had severe upper limb motor impairment. All participants initially demonstrated close to full shoulder PROM. Six participants had shoulder subluxation and five demonstrated scapula malalignment.

Conclusions: Given the severity of upper limb motor impairment, pain and reduced PROM were seen in a small number of participants. The clinical course of shoulder pain and PROM following stroke remains unclear. Large observational studies tracking shoulder characteristics from acute through to rehabilitation settings are needed.  相似文献   


11.
Background: The presence of lower extremity pain may be associated with poorer motor recovery, impaired activities of daily living (ADL), reduced quality of life, and disability in patients with stroke.

Objective: The aims of the study were to describe the characteristics of lower extremity pain conditions and to evaluate the impact of lower extremity pain on clinical variables, and health-related quality of life in patients with stroke.

Methods: One hundred and eighty-five patients with stroke who have self-reported pain in the lower extremity were included in the study. Lower extremity pain characteristics of stroke survivors including etiology, intensity, onset time, frequency, aggravating factors, relieving factors, site, and location of pain were evaluated and recorded. The Brunnstrom motor recovery scale, the functional ambulation category, the mini-mental state examination, the star cancellation test, the beck depression inventory, the Barthel Index, and the Short Form-36 Questionnaire (SF-36) were used.

Results: The causes of lower extremity pain were diagnosed as osteoarthritis (51.1%), central neuropathic pain (28.7%), mixed pain (10.3%), low back pain associated with leg pain (8.6%), greater trochanteric pain syndrome (5.2%), prior hip fracture (2.4%), heterotopic ossification (2%), developmental hip luxation (1%), hallux valgus (0.5%), and malignancy (0.5%). The intensity of lower extremity pain was a significant predictor of cognitive functions, ADL, depression, and all SF-36 subscales except emotional role and vitality. The duration of lower extremity pain was a significant predictor of depression and lower extremity spasticity.

Conclusions: Since lower extremity pain conditions have a significant important influence on clinical variables and health-related quality of life in stroke survivors, early identification and appropriate treatment of the lower extremity pain conditions should be carried out in order to reduce the level of disability in stroke patients.  相似文献   


12.
Objectives: Measures of physical performance were used in intact and community populations. We examined upper and lower extremity physical performance tests among people with Alzheimer's disease.

Method: A total of 367 persons with probable Alzheimer's disease, recruited from an Alzheimer's disease diagnostic center, were given three tests of lower extremity function and two tests of upper extremity function at 6 month intervals for up to 4 years. Gender, race, age and Mini-Mental State Examination (MMSE) score at baseline were used to predict subsequent decline in composite scores of lower and upper extremity function.

Results: At baseline, older age and lower MMSE scores were associated with lower scores on both lower and upper extremity function. Males performed better at baseline on lower extremity tests only. For each point higher on MMSE, a person declined 0.023 Standard Unit (SU) less per year (p = 0.0001) on lower extremity tests and declined 0.019 SU less per year (p < 0.0001) on upper extremity tests.

Conclusion: Physical performance was measured across a range of disease severities and declined over time. Lower cognitive score at baseline predicted faster decline in both lower and upper extremity function. Demographic heterogeneity in decline suggests other predictors may identify factors protective against physical decline.  相似文献   


13.
Background and PurposeTranscranial direct current stimulation (tDCS) is a treatment used in the rehabilitation of stroke patients aiming to improve functionality of the plegic upper extremity. Currently, tDCS is not routinely used in post stroke rehabilitation. The aim of this study was to establish the effects of bihemspheric tDCS combined with physical therapy (PT) and occupational therapy (OT) on upper extremity motor function.MethodsThirty-two stroke inpatients were randomised into 2 groups. All patients received 15 sessions of conventional upper extremity PT and OT over 3 weeks. The tDCS group (n = 16) also received 30 minutes of bihemispheric tDCS and the sham group (n = 16) 30 minutes of sham bihemispheric tDCS simultaneously to OT. Patients were evaluated before and after treatment using the Fugl Meyer upper extremity (FMUE), functional independence measure (FIM), and Brunnstrom stages of stroke recovery (BSSR) by a physiatrist blind to the treatment groupResultsThe improvement in FIM was higher in the tDCS group compared to the sham group (P = .001). There was a significant within group improvement in FMUE, FIM and BSSR in those receiving tDCS (P = .001). There was a significant improvement in FIM in the chronic (> 6months) stroke sufferers who received tDCS when compared to those who received sham tDCS and when compared to subacute stroke (3-6 months) sufferers who received tDCS/sham.ConclusionsUpper extremity motor function in hemiplegic stroke patients improves when bihemispheric tDCS is used alongside conventional PT and OT. The improvement in functionality is greater in chronic stroke patients.  相似文献   

14.
《Clinical neurophysiology》2019,130(5):856-862
ObjectiveWe investigated the potential added value of high-density resting-state EEG by addressing differences with healthy individuals and associations with Fugl-Meyer motor assessment of the upper extremity (FM-UE) scores in chronic stroke.MethodsTwenty-one chronic stroke survivors with initial upper limb paresis and eleven matched controls were included. Group differences regarding resting-state EEG parameters (Delta Alpha ratio (DAR) and pairwise-derived Brain Symmetry Index (BSI)) and associations with FM-UE were investigated, as well as lateralization of BSI and the value of different frequency bands.ResultsChronic stroke survivors showed higher BSI compared to controls (p < 0.001), most pronounced in delta and theta frequency bands (p < 0.0001; p < 0.001). In the delta and theta band, BSI was significantly negatively associated with FM-UE (both p = 0.008) corrected for confounding factors. DAR showed no differences between groups nor association with FM-UE. Directional BSI showed increased power in the affected versus the unaffected hemisphere.ConclusionsAsymmetry in spectral power between hemispheres was present in chronic stroke, most pronounced in low frequencies and related to upper extremity motor function deficit.SignificanceBSI is related to motor impairment and higher in chronic stroke patients compared to healthy controls, suggesting that BSI may be a marker of selective motor control.  相似文献   

15.
Objective: To assess the efficacy of inhibitory repetitive transcranial magnetic stimulation (rTMS) and neuromuscular electrical stimulation (NMES) on upper extremity motor function in patients with acute/subacute ischemic stroke.

Methods: Twenty-five ischemic acute/subacute stroke subjects were enrolled in this randomized controlled trial. Experimental group 1 received low frequency (LF) rTMS to the primary motor cortex of the unaffected side + physical therapy (PT) including activities to improve strength, flexibility, transfers, posture, balance, coordination, and activities of daily living, mainly focusing on upper limb movements; experimental group 2 received the same protocol combined with NMES to hand extensor muscles; and the control group received only PT. Functional magnetic resonance imaging (fMRI) scan was used to evaluate the activation or inhibition of the affected and unaffected primary motor cortex.

Results: No adverse effect was reported. Most of the clinical outcome scores improved significantly in all groups, however no statistically significant difference was found between groups due to the small sample sizes. The highest percent improvement scores were observed in TMS + NMES group (varying between 48 and 99.3%) and the lowest scores in control group (varying between 13.1 and 28.1%). Hand motor recovery was significant in both experimental groups while it did not change in control group. Some motor cortex excitability changes were also observed in fMRI.

Conclusion: LF-rTMS with or without NMES seems to facilitate the motor recovery in the paretic hand of patients with acute/subacute ischemic stroke. TMS or the combination of TMS + NMES may be a promising additional therapy in upper limb motor training. Further studies with larger numbers of patients are needed to establish their effectiveness in upper limb motor rehabilitation of stroke.  相似文献   


16.
Abstract

Background:

Deficiencies in motor control are one of the largest challenges faced by stroke survivors in regaining their independence after stroke.

Objective:

This study investigated movement efficiency in people with and without stroke during both unimanual and bimanual upper extremity reaching tasks.

Method:

Twenty-five participants (12 with stroke and 13 age-matched controls) between the ages of 36–69 years randomly experienced testing conditions involving reaching forward unimanually and bimanually at a preferred speed in a single session. Kinematic and kinetic outcomes included movement time, movement units, peak velocity, and percentage of movement time to peak velocity.

Results:

In stroke participants, the unimpaired limb accommodated its movements to that of the less efficient paretic limb during bimanual conditions indicating yoked movement efficiency because its performance was more efficient (P?<?0.05) in unilateral trials, whereas the impaired limb's performance did not differ between the unimanual and bimanual conditions (P>0.05). Control subjects elicited greater movement efficiency than participants with stroke.

Conclusion:

Motor efficiency of the unimpaired upper extremity may be adversely influenced when yoked with the impaired limb during symmetrical simple movements in persons with stroke. As such, motor efficiency is not exclusively limited to the impaired side, the effects of which may be task dependent.  相似文献   

17.
Background: Recovery from aphasia impacts the quality of life in stroke patients but remains difficult to predict. Some neuroanatomical factors combined with anagraphical factors contribute to the prediction of longitudinal outcomes, but still fail to predict changes in severity of symptoms. Among the language features predicting recovery from aphasia, production scores such as repetition or phonology seem to be more relevant predictors than only severity. As motor cortex is strongly involved in language processes, both production and perception, the present study builds on the hypothesis that assessment of the anatomo-functional motor pathways could improve predictive models on top of factors based on neuroanatomy.

Aim: In this prospective longitudinal study, we aimed to determine whether the integration of an electrophysiological measure of the motor network using Motor Evoked Potentials (MEPs) with an anatomical approach—diffusion-weighted MRI— in the acute phase of stroke can improve the prediction of recovery from post-stroke aphasia.

Methods and Procedures: Fifteen aphasic patients were included in the post-stroke acute phase. Electrophysiological assessment exploring resting motor threshold ratio (rMTr) of the two upper-limbs and neuroanatomy exploration using MRI and diffusion tensor imaging were performed in the acute phase. Language impairment was assessed at the same stage and six months after the stroke. Multivariate regression analyses were carried out on aphasia severity score at M6, on recovery rates (change of severity) and on speech and language features as the dependent variables.

Outcomes and Results: A first-level model, including only clinical variables (i.e., the initial severity) predicted severity at six months. When the rMTr of upper limbs was added in a second-level model, the predictive power significantly increased from 51% to 79%, as well as adding in a third-level model rMTr of upper limbs and the initial fibers number ratio (iFNr) of the corticospinal tracts (51% to 80%). With the changes in severity as the dependent variable, the same factors made a significant contribution and the predictive power of a second-level model increased from 23% to 50% to the same extent as in a third-level model (23% to 51%). A similar improvement when adding MEPs was noted for the prediction of articulatory agility and naming skills.

Conclusions: Our results suggest that MEPs of upper limbs measured within 15days post-stroke are strong determinants of the prediction of longitudinal severity of post-stroke aphasia as well as of changes in symptoms and that the combination of electrophysiological and anatomical biomarkers improve this prediction.  相似文献   


18.
Background: Training of the upper limb (UL) is limited in stroke rehabilitation, and about 50% of stroke survivors do not regain useful function in their upper limb.

Objectives: This study explored what factors affect rehabilitation and use of upper limb after stroke from a stroke survivor and healthcare professional perspective to better understand low engagement in UL rehabilitation in the chronic stages of stroke.

Method: Eight chronic stroke survivors and 21 healthcare professionals took part in semi-structured interviews or in one of three focus groups, respectively.

Results: Thematic analysis revealed three main themes: Availability of resources, Healthcare professional–patient relationship, and Psychosocial factors. Availability of resources and Healthcare professional–patient relationship indicated that due to resource pressures and a lack of communication and education, positive upper limb rehabilitation behaviors (e.g. engaging and integrating the upper limb in daily activity) were not always established in the early stages post-stroke. Psychosocial factors illustrated the cognitive and psychological barriers to sustained engagement with upper limb rehabilitation.

Conclusion: The findings indicate that stroke survivors and healthcare professionals have very similar understandings of barriers to UL activity, and positive upper limb rehabilitation behaviors are not always established early in recovery post-stroke. Increased resources and healthcare professional–patient relationships seem key factors to establishing positive perceptions of UL rehabilitation. Addressing psychosocial issues and resource limitations may help sustain engagement with UL rehabilitation.  相似文献   


19.
Abstract

Background and Aims: Mirror therapy (MT) is an alternative therapeutic intervention that uses the interaction of visuomotor-proprioception inputs to enhance movement performance of the impaired limb. Despite strong evidence for task-specific training in stroke, MT has been investigated using nontask movements. The aim of this pilot study was to assess the effectiveness of task-based MT on motor recovery of the upper extremity in chronic stroke patients. Method: In a pretest-posttest single-group design, a convenience sample of 13 chronic stroke patients at an occupational therapy department of a rehabilitation institute was assessed on a task-based MT intervention. Participants received a task-based MT program, performing various tasks by the less affected upper extremity and observing in the mirror box along with conventional management, 4 days per week for 4 weeks. Fugl-Meyer Assessment (FMA), which includes subsection upper extremity (FMA-UE) and subpart upper arm (FMA-UA) and hand (FMA-WH), was used as an outcome measure. Results: Participants showed no significant improvement for FMA-UE and FMA-UA at postassessment. FMA-UE changed from 43% to 51%. Post FMA-UA score showed only 2% improvement. However, there was statistically significant improvement on mean scores of FMA-WH at postassessment (16.21 ± 3.06) as compared with the prescores (12.29 ± 3.1; P < .05). FMA-WH improved from 41% to 54%. Conclusions: The preliminary findings suggest that task-based MT is effective in improving wrist and hand motor recovery in chronic stroke patients. Further studies in the form of randomized trials are needed to validate its effectiveness.  相似文献   

20.
Background: Neuromuscular electrical stimulation (NMES) and noxious thermal stimulation (NTS) have been developed and incorporated in stroke rehabilitation.

Objective: This study aimed to compare the effects of NMES, NTS, and the hybrid of NMES and NTS (“Hybrid”) on motor recovery of upper extremity (UE) for patients with stroke.

Methods: We conducted a prospective, single-blind randomized controlled trial with concealed allocation. Forty-three patients with chronic stroke (onset >6 months) were randomly assigned to three groups (NMES, NTS, and “Hybrid”). In addition to conventional rehabilitation, participants received 30 min of NMES or 30 min of NTS or 15 min of NTS followed by 15 min of NMES. The treatment period was 8 weeks, 3 days/week, 30 min/time. The UE subscale of Fugl-Meyer assessment (UE-FMA, the primary outcome), Motricity index, modified Ashworth scale, and Barthel index were administered by a blinded assessor at baseline, posttreatment, and one-month follow-up.

Results: Most of the participants had mild-to-moderate disability in activity of daily living. No significant differences in the outcome measures at posttreatment and one-month follow-up were found among the NMES group (n = 13), NTS group (n = 13), and the hybrid of NMES and NTS group (n = 17). However, significant score changes in UE-FMA (p < 0.025) from baseline to posttreatment and one-month follow-up were found for the “Hybrid” group.

Conclusions: This study reveals that the hybrid of NMES and NTS therapy appears to be beneficial to UE recovery after stroke but is not superior to NMES or NTS alone.  相似文献   


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