产业预测:增长率15%

专家分析,2004年的医药生产形势呈现以下特点:一是我国化学制药的“比较优势“在竞争中得以较好发挥,产品出口扩大机遇增大,中国作为世界原料药重要生产基地的地位进一步巩固和提高;二是医药产品中的半合成抗菌素药品尤其是头孢类产品替代传统抗生素制剂品种的步伐加快,而头孢类产品将成为城市的用药主流;三是日益激烈的市场竞争,将加快药品生产集中度的提高,医药企业在竞争中将出现两极分化,市场和效益越来越集中于行业领头企业.……     

我国中药出口 SWOT分析与战略选择——基于胃药的调查

随着经济全球化和国外对中药的认可,国外生产的"洋中药"因科技含量高、产品符合国际标准,大举进入国际医药市场,给我国中药产业带来了巨大的冲击。以治疗胃病的中药为例,对我国中药出口的优势(strengths)、劣势(weakness)、机遇(opportunities)和威胁(threats)进行具体分析,提出了发展我国中药出口的品牌战略、合作和营销战略,以期为我国中药企业产品出口提供借鉴。     

从显著下滑转向企稳回升：2009年我国西药类商品进出口情况分析

2009年，我国西药类商品进出口从显著下滑转向企稳回升，医药外贸行业经受住了国际金融危机的严峻考验。通过对全年西药类出口市场、出口企业、西药原料药出口、西成药出口、生化药出口等的对比研究，分析了西药类商品出口运行情况；通过对进口企业、进口市场、进口商品情况的对比，总结了西药进口情况；并对2001年的西药类商品进出口地总体情况进行了预测，并提出5条建议性的措施以变不利因素为有利因素。     

近几年来出口退税率的调整对江苏外贸经济的影响

出口退税政策是我国宏观经济调控的一个重要工具.我国自1985年实施出口退税政策以来,多次进行了出口退税政策的调整.出口退税率的调整使江苏出口总额增速,引起贸易顺差、出口产品、贸易方式、外贸区域等方面出现不同的变化,出现了贸易总额高速增长、顺差不断累加、高附加值产品占主流、一般贸易向加工贸易转移、外贸区域多元化.同时,出口退税率的调整也给江苏外贸经济的发展带来了一些问题,建议国家制定分地区出口退税率、进一步推进外贸区域多元化、加强江苏企业自身的核心竞争力、走工贸一体化道路、建立中央出口退税专项转移支付制度.     

金纳多对中国植物药发展的启示

植物药现已成为世界医药市场的一个重要组成部分。然而,我国的天然植物药制剂明显落后于其他国家,在国际植物药市场中占主导地位的是欧洲草药制剂和日、韩汉方制剂。本文通过对世界植物药中最具影响力的产品——金纳多(银杏叶提取物)的生产工艺、知识产权、产品标准和市场等方面的深入分析,提出了中国目前及未来植物药将如何进行发展的一些启示和建议。     

金纳多对中国植物药发展的启示

植物药现已成为世界医药市场的一个重要组成部分。然而，我国的天然植物药制剂明显落后于其他国家，在国际植物药市场中占主导地位的是欧洲草药制剂和日、韩汉方制剂。本文通过对世界植物药中最具影响力的产品——金纳多（银杏叶提取物）的生产工艺、知识产权、产品标准和市场等方面的深入分析，提出了中国目前及未来植物药将如何进行发展的一些启示和建议。     

2007年西药类商品出口增幅超15%

“十一五”期间,为推动医药行业科技进步和增强国际竞争力,国家各部委陆续出台一系列政策,从技术、法规层面进行系统推进,以支持医药产业升级,帮助医药企业走出国门。这将对我国医药产品出口起到重要的推动作用。第七届世界制药原料中国展于6月19日至21日在上海新国际博览中心隆重举行,会前有专家对中国西药市场进行了乐观预测,指出今年西药类商品出口快速增长势头将继续保持,预计全年增幅有望保持在15%以上。     

磷霉素钠杯有奖征文通知

东北制药总厂位于辽宁省沈阳市,是我国最大的以化学合成为主、兼有生物发酵和制剂产品的综合性制药工业企业之一,是我国医药产品重要的生产和出口基地。企业资产35亿元,17个生产分公司,拥有国家级企业技术开发中心——医药工业研究院、设计院、环保研究所、质量检测控制中心等部门,并设有博士后工作站,拥有与国外客商直接进行贸易和洽谈的进出口公司,聚集了一大批享有盛誉的顶尖级专家和管理人才,享有国务院特殊津贴者12人,拥有国内制药企业第一位中国工程院院士。     

现代中医药产业化发展探讨(二)——中药制剂部分

中药现代化的落脚点是中药产品 ,其核心是中药制剂的质量。我国加入WTO后其医药市场必将与世界医药市场接轨 ,中药的生产、管理、检测等技术能否真正做到产业化、现代化 ,是影响中药进入国际医药市场的瓶颈。文章根据我国中药制剂的现状 ,对制剂新工艺以及中药复方新药的产业化发展进行了探讨。     

我国医院中药制剂的现状和发展策略

随着我国正式加入世界贸易组织，我国的中药事业正面临着严峻的挑战和前所未有的发展机遇。发掘我国中药的宝贵资源，走发展中药之路，医院中药制剂有着极大的开发潜力。近年来，随着国家加大对医药行业的管理力度，医药市场趋于规范，药品监督管理工作逐渐理顺及工业制剂的飞速发展，医院制剂正面临着严峻的挑战，中药制剂如何适应这种变化，更好地发挥其自身优势，已成为医院制剂发展的主要内涵之一。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…