血清肌钙蛋白T动态监测预测心肌梗塞面积的研究

对２４例急性心肌梗塞（ＡＭＩ）患者心肌梗塞后肌钙蛋白Ｔ（ＴｎＴ）释放量与心肌断层显像测定梗塞相对面积以及左室射血分数（ＬＶＥＦ）的相关性进行研究。结果显示：２４小时内ＴｎＴ峰值与心肌梗塞相对面积无明显相关性（ｒ＝０．３３，Ｐ＞０．０５）；２４小时后ＴｎＴ峰值与心肌梗塞面积呈正相关（ｒ＝０．８１，Ｐ＜０．０１）；累积ＴｎＴ（ΣＴｎＴ）释放量与相对梗塞面积呈显著正相关（ｒ＝０．９０，Ｐ＜０．０１）；２４小时后ＴｎＴ峰值与ＬＶＥＦ呈显著负相关（ｒ＝－０．５４，Ｐ＜０．０１）。表明，ＡＭＩ后ＴｎＴ的后期释放峰值及释放量是判断心肌梗塞面积的良好参数，对预测心肌梗塞后心功能状态亦有参考价值。     

倾斜试验配合心得安试验对心血管疾病的诊断价值

目的对功能性和器质性Ｔ波异常者倾斜前后Ｔ波改变的不同表现及对心得安试验阳性率，结合冠状动脉（冠脉）造影血管病变的严重程度加以分析。方法采用ＤＴ－１型自动倾斜床测定倾斜前后心率，血压及１２导联心电图及其服用心得安以后的变化。对器质性Ｔ波异常、功能性Ｔ波异常及对照组三组进行比较。结果（１）功能组心得安阳性率为８５％，器质组心得安阳性率为１５％（Ｐ＝０．００００）；（２）功能组心得安试验阳性倾斜前后心率均明显高于对照组（Ｐ＝０．０１６、０．００２），服用心得安２小时后平卧及倾斜后的平均心率均明显低于用药前（Ｐ＝０．０００）；（３）功能组心得安试验阳性服用心得安２小时后平卧位ＱＴｃ值明显小于服药前（Ｐ＝０．０１９），器质组心得安试验阴性服用心得安２小时后ＱＴｃ值与用药前无明显变化（Ｐ＞０．５）；（４）功能组倾斜后Ｔ波异常加重，服用心得安后明显改善，器质组倾斜后Ｔ波伪改善，心得安无效。结论功能性Ｔ波异常与β受体应答性的改变有关，而器质性Ｔ波异常则主要与缺血部位心肌β受体分布的不均一性有关     

肌钙蛋白T对缺血性心肌细胞损伤的诊断及其对溶栓疗效的判定价值

目的：评价肌钙蛋白Ｔ（ＴｎＴ）血清浓度变化对缺血性心肌细胞损伤的诊断及其对溶栓疗效的判定价值。方法：采用酶联免疫吸附法测定１６１例急性心肌梗死及５７例心绞痛患者ＴｎＴ浓度动态变化。结果：急性心肌梗死发病后２、４、６小时ＴｎＴ的阳性率分别为５８．０％、６８．６％、９０．９％，１０小时至５天为１００．０％，７、１０、１４、１７、２１天分别为９１．７％、６６．７％、２２．０％、１２．１％、９．２％，明显高于血清肌酸激酶及血清肌酸激酶ＭＢ同工酶（Ｐ＜０．０１）。ＴｎＴ诊断急性心肌梗死的敏感性和特异性为１００．０％及９１．８％。溶栓再通组ＴｎＴ呈双峰性曲线，未通组呈单峰性曲线，其峰值时间（４２．０２±１．６５小时）早于双峰性曲线的晚期峰时间（７５．１０±１．３３小时，Ｐ＜０．０１），其浓度（１４．６２±１．９１μｇ／Ｌ）明显高于双峰性曲线的晚期峰值（７．０２±０．８５μｇ／Ｌ，Ｐ＜０．０１）。结论：ＴｎＴ是一灵敏度高、特异性强的心肌损伤性血清标志物，对急性心肌梗死溶栓有无再通有一定判定价值。     

肌钙蛋白T检测对不稳定性心绞痛患者的预后判断

目的本研究旨在评价血清肌钙蛋白Ｔ（ｃＴｎＴ）定量测定对不稳定性心绞痛患者的预后判断价值。方法对６０例不稳定性心绞痛患者（ＵＡＰ）、１８例稳定心绞痛患者及２０例健康人分别进行血清ｃＴｎＴ、肌酸激酶（ＣＫ）和其同工酶（ＣＫ－ＭＢ）的测定，并观察住院期间的心性事件发生率。结果６０例ＵＡＰ患者中３２例（５３％）ｃＴｎＴ≥０．３μｇ／Ｌ，明显高于余２８例（分别为０．７５±０．２４μｇ／Ｌ和０．１２±０．０４μｇ／Ｌ，Ｐ＜０．００１），但ＣＫ、ＣＫ－ＭＢ差异并无显著性。不稳定心绞痛患者中ｃＴｎＴ升高组３０天内其发生急性心肌梗塞、心脏性猝死、顽固性心绞痛的发生率明显高于ｃＴｎＴ正常值（４３．８％比７．１％，Ｐ＜０．０１）；对上述心脏事件，定量ｃＴｎＴ检测的敏感性为８７．５％，阴性预期值达９２．９％，准确性为６６．７％。结论ｃＴｎＴ是反映心肌细胞损伤的灵敏性、特异性均较好的生化指标；ｃＴｎＴ升高对判断不稳定心绞痛患者预后有较好的预测价值。     

高血压病左室肥厚的室性心律失常与心室晚电位关系的探讨

检测３２２例有或无左室肥厚（ＬＶＨ）高血压病患者的心室晚电位（Ｌｐ）和２４小时动态心电图。结果发现：Ｌｐ阳性检出率为１８．３％，室性心律失常（ＶＡ）检出率为５３．１％。ＬＶＨ者和无ＬＶＨ者Ｌｐ阳性检出率分别为３４．９％和９．９％（Ｐ＜０．０１）；ＶＡ的检出率为８１．７％和３８．５％（Ｐ＜０．０１）。并发现ＬＶＨ又Ｌｐ阳性者ＶＡ、复杂ＶＡ及室速（ＶＴ）检出率（１００％、９７．４％、８１．９％）均高于ＬＶＨ的Ｌｐ阴性者（７１．８％，Ｐ＜０．０１，２１．１％、１．４％，Ｐ＜０．００１）和无ＬＶＨ的Ｌｐ阳性者（７６．２％，Ｐ＜０．０１，５７．１％、４７．６％，Ｐ＜０．００１）。表明Ｌｐ与高血压病的ＶＡ，尤其是复杂ＶＡ及ＶＴ具有密切关系。     

急性心肌梗死溶栓治疗肌钙蛋白T动态变化

目的：观察静脉溶栓治疗急性心肌梗死（ＡＭＩ）患者肌钙蛋白Ｔ（ＴｎＴ）的血清浓度动态变化特点，探讨其对溶栓疗效判定价值。方法：采用全自动酶联免疫吸附测定（ＥＬＩＳＡ）法，测定３９例ＡＭＩ患者肌钙蛋白Ｔ血清浓度变化。结果：１４例ＡＭＩ溶栓再通组的肌钙蛋白Ｔ第１高峰时间（１３．４３±４．０３小时）较１３例溶栓未通组（１８．６２±４．０３小时，Ｐ＜０．０１）及１２例非溶栓组（２４．００±１４．８７小时，Ｐ＜０．０５）明显前移；肌钙蛋白Ｔ发病第１２小时／第７２小时比值，在溶栓再通组（２．４４±１．５２）大于溶栓未通组（１．１２±０．８３）及非溶栓组（１．００±１．０３，Ｐ均＜０．０５）；对ＡＭＩ溶栓再通预测的敏感性、特异性及准确性：在以肌钙蛋白Ｔ第１峰时间≤１４小时为界时分别为７１．４％、８４．６％、７８．０％，在肌钙蛋白Ｔ第１２小时／第７２小时比值≥２．０时为６６．７％、８４．６％及７５．７％。结论：肌钙蛋白Ｔ对ＡＭＩ溶栓疗效具有一定的判定价值。     

巨细胞病毒感染与动脉粥样硬化的临床研究

目的探讨人类巨细胞病毒（ＨＣＭＶ）感染、肿瘤坏死因子（ＴＮＦ）及血浆内皮素（ＥＴ）浓度与动脉粥样硬化的关系。方法采用间接免疫荧光技术测定急性心肌梗塞组（２０例）、冠状动脉狭窄组（２０例）及正常对照组（３０例）血清人类巨细胞病毒抗体，用放射免疫法测定血清ＴＮＦ及ＥＴ的浓度。结果急性心肌梗塞组ＨＣＭＶＩｇＭ阳性１４例（７０％），ＨＣＭＶＩｇＧ阳性２０例（１００％），ＨＣＭＶＩｇＭ、ＩｇＧ双阳性１４例（７０％）；冠状动脉狭窄组ＨＣＭＶＩｇＭ阳性１９例（９５％），ＨＣＭＶＩｇＧ阳性１９例（９５％），ＩｇＭ、ＩｇＧ双阳性１８例（９０％）；正常对照组ＨＣＭＶＩｇＭ阳性６例（２０％），ＨＣＭＶＩｇＧ阳性２６例（８２％），ＩｇＭ、ＩｇＧ双阳性６例（２０％），与正常对照组比较，差异有显著性（Ｐ＜０００１，Ｐ＜００５，Ｐ＜０００１）；冠心病急性心肌梗塞组、冠状动脉狭窄组与正常对照组相比，血清ＴＮＦ、血浆ＥＴ显著增高（Ｐ＜０００１）。结论患者的ＨＣＭＶ感染、内皮细胞受损和ＴＮＦ作用可能参与了冠心病发生发展的过程。     

46例平板运动试验假阳性和假阴性原因分析

目的 探讨平板运动试验（ＴＥＴ）假阳性和假阴性的原因。方法 选择本院１９９７～１９９９年临床拟诊为冠心病并行ＴＥＴ及冠状动脉造影（ＣＡＧ）的住院患者２７８例。结果 假阳性（ＴＥＴ阳性而ＣＡＧ阴性）３２例,其中植物神经功能玄紊乱１１例,高血压病９例,糖尿病６例,其它疾病６例。假阴性（ＴＥＴ阴性而ＣＡＧ阳性）１４例。其中冠脉单支病变１２例,双支和三支病变各１例。结论 ＴＥＴ如能排除植物神经功能紊乱、高     

心肌肌钙蛋白T对不稳定型心绞痛患者心脏事件的预测价值(摘要)

本文探讨血清心肌肌钙蛋白Ｔ（ｃＴｎＴ）对不稳定型心绞痛患者心脏事件的预测价值。１　资料与方法　　选择了１９９６年３月至１９９８年３月在我院住院治疗的不稳定型心绞痛（ＵＡＰ）患者２０６例,按Ｂｒａｕｎｗａｌｄ分级标准分为３级;入院后０～４小时及１２～２４小时静脉采血各１次,检测血清ｃＴｎＴ浓度;随访时间定为入院后６个月内。血清ｃＴｎＴ的测定方法为酶联免疫吸附一步夹心法。血清ｃＴｎＴ的正常值：≤０．２μｇ／Ｌ。　　统计学处理：数据以ｘ±ｓ表示;两组间均数的比较用ｔ检验;两组间率的比较用四格表χ２检…     

冠状动脉造影斑块形态与冠状循环中血浆及血清血栓素B_2及6－酮－前列环素F_（1α）的关系

冠心病患者按冠状动脉造影斑块的形态学分为三组，非冠心病患者作为对照。同时采集受试者冠状静脉窦（ＣＳ）及升主动脉（ＡＯ）血作血浆及血清血栓素Ｂ２（ＴＸＢ２）及６－酮－前列环素Ｆ１α（６－ｋｅ－ｔｏ－ＰＧＦ１α）的测定。结果显示，冠状动脉造影表现为Ⅱ型斑块（表面不规则）的患者血浆ＴＸＢ２ＣＳ／ＡＯ比值明显高于Ⅰ型斑块（表面光滑）、Ⅲ型斑块（长段不规则）的患者及正常对照组（Ｐ＜０．０５）；而Ⅱ型斑块者血清ＴＸＢ２ＣＳ／ＡＯ比值明显低于对照组（Ｐ＜０．０５）；血浆及血清６－ｋｅｔｏ－ＰＧＦ１α四组间差别无显著性。结果说明，Ⅱ型斑块的患者冠状循环中血小板明显激活，ＴＸＡ２大量释放。从而从临床生化的角度提示，Ⅱ型斑块常代表局部斑块破裂及（或）局部血栓形成     

Prediction of coronary artery disease using post exercise T wave change

In the evaluation of the exercise stress test, conventional electrocardiographic criteria using 1 or 2 mm ST segment depression below the isoelectric line yields many false positive results and is not so useful to predict the severity of coronary artery disease. In this study, we have attempted to predict the presence and the severity of coronary artery disease from the post exercise T wave change. Fifty-six patients who had positive treadmill exercise test results by conventional ST segment criteria and underwent selective coronary arteriography were studied. T wave change was defined as inversion or biphasic change in one or more of leads aVF, V4, V5, V6 during the recovery phase, and in the cases who showed T wave changes, T wave configuration were also analysed. Seventeen of 28 patients with and 11 of 28 patients without significant coronary artery disease showed post exercise T wave changes. This difference was not statistically significant. But in the cases who showed T wave changes, the maximum amplitude of the negative component of T wave was significantly greater in the true positive group than in the false positive group. And the development of deeply negative component (more than 1.5 mm) indicated the presence of multivessel coronary artery disease. In the cases who showed the negative component of T wave less than 1 mm, the characteristics of T wave configuration including the amplitude, height of positive component, and the depth from the isoelectric line were different between the 2 groups. These results suggest that careful observation of T wave during the recovery phase is useful to improve the diagnostic accuracy of the exercise electrocardiogram.     

Relationship of serum cardiac markers following successful percutaneous coronary intervention and subsequent exercise capacity in patients with chronic stable angina: a pilot study

We performed a pilot study to assess the significance of modest, asymptomatic, elevated serum cardiac markers--troponin T (TnT) and creatinine kinase-MB (CK-MB)--18-24 h following successful elective percutaneous coronary intervention (PCI) and to explore their relationship with changes in aerobic exercise capacity, as measured by peak oxygen consumption (VO2), 6 weeks following the procedure. Twenty-three patients with single-vessel disease and chronic angina performed an incremental cardiopulmonary exercise test before and 6 weeks after successful uncomplicated PCI. A venous blood sample was taken at rest before PCI and 18-24 h after the procedure. Successful PCI resulted in a trend towards an increased peak VO2 [21.62 +/- 0.64 (pre) vs. 23.03 +/- 0.75 ml/ kg/min (post), p = 0.07; mean +/- SEM]. There was a significant increase [median (IQR)] in TnT, from 0.00 (0.00) microg/l at baseline increasing to 0.02 (0.03) microg/l at 18-24 h, p = 0.002. CK-MB levels showed no significant difference. In the group of 15/23 (65%) patients with an elevation in serum TnT (>/=0.01 microg/l), 18-24 h after successful PCI, there was no significant increase in peak VO2 [23.31 +/- 0.96 (pre) vs. 23.89 +/- 1.09 ml/kg/min (post), p = 0.57]. In 8 (35%) patients with no rise in TnT at 18-24 h, a significant increase in peak VO2 was observed following successful PCI [23.10 +/- 0.91 (pre) vs. 25.09 +/- 0.75 ml/kg/min (post), p = 0.02]. Although 7 of these 8 patients increased their peak VO2, the absence of a TnT rise at 18-24 h was not significantly associated with an increase in peak VO2 following successful PCI (p = 0.18). To confirm these interesting initial results and investigate the relationship of serum cardiac markers following successful PCI and subsequent exercise capacity, further studies are required.     

平板运动试验时U波倒置的临床意义

目的 通过对比平板运动试验中U波倒置和ST段压低的发生情况,评价U波倒置对诊断冠心病的临床意义.方法 选择我院内科2011年8月～2013年2月心内科行平板运动试验检查的患者151例,其中男性76例,平均年龄57.9±5.16岁;女性75例,平均年龄55.4±7.09岁.对平板运动试验中出现的U波倒置和ST段下移进行对比研究和分析.结果 151例患者中,平板运动试验阳性55例,阴性96例;U波阳性33例,阴性118例.平板运动试验的阳性率36.4％,U波阳性率21.8％,卡方检验显示p=0.014;平板运动试验阳性的患者中冠脉造影阳性49例,阴性6例;U波阳性的患者中冠脉造影阳性27例,阴性6例.平板运动试验阻性的敏感性89.1％,U波阳性的敏感性81.8％,卡方检验显示p=0.578.结论 平板运动试验中U波倒置发生率较ST段下移发生率低,但冠脉造影确诊的冠心病患者中,U波倒置的敏感性和ST段下移相似,建议作为冠心病患者平板运动的阳性指标之一.     

Variability of negative T wave in hypertrophic cardiomyopathy: possible role of beta-adrenergic function

To investigate the variability and the mechanism of negative T waves in hypertrophic cardiomyopathy (HCM), especially giant negative T waves in apical hypertrophy, from view point of adrenergic function, ECG was studied by treadmill exercise test and under administrations of beta-adrenergic agonist (isoproterenol) and antagonist (propranolol) in 33 patients with HCM and negative T waves. Apical hypertrophy was seen in 16 cases, and giant negative T waves were seen in 24 cases. By treadmill exercise test, negative T waves became less deep in all cases of HCM (-1.2 +/- 0.5 mV-----0.6 +/- 0.5 mV, p less than 0.001). The higher exercise level the patients attained, the less deep the negative T waves became. Isoproterenol caused the same reversal of negative T waves as the exercise test, but heart rate and rate pressure product attained by isoproterenol were significantly smaller than those by exercise. R wave amplitude did not change with isoproterenol. Propranolol made negative T waves deeper at rest and inhibited the reversal of negative T waves caused by exercise. In conclusion, negative T wave in HCM, especially giant negative T wave in apical hypertrophy, is variable. Beta-adrenergic function may be at least one of its mechanisms.     

运动平板试验对青年冠状动脉粥样硬化性心脏病的诊断价值

目的评估运动平板试验对青年冠状动脉粥样硬化性心脏病（冠心病）患者的诊断意义。方法选择有典型胸痛症状的青年男、女患者各200例行运动平板试验,择期进行冠状动脉造影,对其结果进行对照分析。结果男性患者冠状动脉造影结果阳性142例中运动平板试验阳性136例,阴性6例;男性患者冠状动脉造影结果阴性58例中运动平板试验阳性10例,阴性48例。女性患者冠状动脉造影结果阳性90例中运动平板试验阳性84例,阴性6例;女性患者冠状动脉造影结果阴性110例中运动平板试验阳性56例,阴性54例。运动平板试验诊断男性青年冠心病的特异性和准确性高于女性,差异有统计学意义（82．8％vs．46．5％,P〈0．01：93．0％弧60．0％,P〈0．01）。结论运动平板试验对男性青年冠心病的诊断符合率高于女性。     

C-reactive protein as an independent marker of prognosis in acute coronary syndrome: comparison with troponin T

BACKGROUND: It has been suggested that inflammatory processes play a role in the pathogenesis of acute coronary syndromes (ACS). C-reactive protein (CRP) is a classic acute phase protein. It is yet unclear whether, in addition to established markers as troponin T (TnT), determination of CRP in patients admitted for ACS contributes significantly to the diagnosis and prognosis of ACS. PATIENTS AND METHODS: We investigated 50 patients with ACS (59.4 SD 13.9 years) in the first hour after admission and 4-24 h later with respect to TnT (Elecsys, Roche Diagnostics) and CRP (biokit, modified Quantex CRP plus, analytical sensitivity 0.02 mg/dL). Fifty percent of the patients were classified as having unstable angina retrospectively. All patients were followed in the 6 weeks post discharge regarding death and recurrent ACS. RESULTS: The cumulative event rate at 6 weeks after discharge was 62.5% for patients being CRP and TnT positive compared to 35.3% in TnT positive and CRP negative patients. In TnT negative patients a positive CRP test predicted 33.3% of events and 28.8% of patients negative for CRP and TnT had events at 42 days post discharge. Logistic regression analysis regarding the primary endpoint including TnT and CRP (4-24 h values), age, gender and diagnosis resulted in independent prediction of ACS or death by TnT (cutoff 0.1 microgram/L, p = 0.048, odds ratio = 7.5) and CRP (cutoff 0.862 mg/dL, p = 0.026, odds ratio = 5.3). Sensitivity/specificity for AMI diagnosis were 69.6%/75% for TnT and 12%/72% for CRP in the first hour and 91.3%/68.2% for TnT and 68%/72% for CRP 4-24 h later. CONCLUSIONS: Besides TnT, high sensitivity CRP determination has no additional value for early AMI diagnosis. The prognosis of these patients during the first 24 hours is significantly and independently predicted by CRP measurements in addition to troponin T.     

Clinical significance of prominent negative T waves induced by exercise test

The significance of deep T wave inversion during and after exercise in patients with coronary artery disease has not been studied well. Using the treadmill exercise test (modified Bruce's protocol) and coronary arteriography, we evaluated 361 patients suspected of having coronary artery disease. Results were compared for patients who developed significant T wave inversions of greater than 8 mm (prominent negative T wave: PNT) and for patients who had significant down-sloping ST depressions (DS). Sixteen patients had PNT (4%) which became maximum three to five min after exercise, and ranged in depth from 8 to 15 mm (10.9 +/- 2.4 mm). There were 83 patients with DS (23%). Exercise duration was 3.3 +/- 1.4 min in the PNT group and 4.4 +/- 1.9 min in the DS group (p less than 0.01). Prevalence of three-vessel disease or left main trunk disease was 88% (14 patients) in the PNT group, 28% in the DS group, and 19% (70 patients) in the entire 361 patients. Among the 14 patients who had three-vessel disease or left main trunk disease in the PNT group, the degree of multiple stenoses exceeded 90% in the major coronary arteries and that of the left main trunk stenosis exceeded 75%. The two remaining patients included one with two-vessel disease and severe 99% narrowing of the major coronary arteries and one patient having one-vessel disease with vasospastic angina during exercise. Prevalence of coronary revascularization was 69% in the PNT group and 36% in the DS group (p less than 0.025).(ABSTRACT TRUNCATED AT 250 WORDS)     

平板运动试验与动态心电图联合检测对冠状动脉病变的预测价值

目的 为明确平板运动试验与动态心电图联合检测对冠状动脉病变的预测意义。方法 选取冠状动脉造影患者、且造影前或造影后2月内作平板运动试验和动态心电图者185例,冠状动脉造影以通用直径法确定冠状动脉狭窄程度和范围,并与平板运动试验和动态心电图结果对比观察。结果 95例平板运动试验和动态心电图结果均阳性者,94例存在冠状动脉病变,7例仅动态心电图阳性者6例有冠状动脉病变而53例仅平板运动结试验阳性者42例有冠状动脉病变,30例动态心电图和平板运动结试验均阴性者仅1例有轻度冠状动脉病变。结论 平板运动试验与动态心电图联合检测可初步估测冠状动脉狭窄。     

Features of the exercise test that reflect the activity of ischemic heart disease out of hospital

To better understand the relationship between the transient myocardial ischemia seen during an exercise test and ischemic activity out of hospital, 39 patients with well-documented coronary artery disease underwent standard treadmill exercise testing (Bruce protocol) and 24 to 48 hr of continuous ambulatory electrocardiographic monitoring during normal daily activities. A total of 245 episodes of transient ischemia were recorded in 21 of 32 patients with positive exercise electrocardiograms (group I), whereas seven patients with negative test results (group II) had no episodes of transient ischemia, during monitoring out of hospital (p less than .01). Certain measures in the exercise test were related to the severity of ischemia out of hospital: there were more episodes and a greater total duration of transient ischemia per 24 hr of ambulatory monitoring in patients who developed ischemic electrocardiographic changes before 6 min of exercise (p less than or equal to .021) or at a heart rate of less than 150 beats/min (p = .005) and in those in whom these ST segment changes persisted for more than 5 min after exercise (p less than or equal to .016). In contrast, there was no relationship between transient ischemia out of hospital and the commonly quoted exercise variables: chest pain, total exercise duration, and the maximum levels of heart rate, systolic blood pressure, and double product. Thus, patients with coronary artery disease and negative exercise electrocardiograms are most unlikely to experience active ischemia during normal daily life.(ABSTRACT TRUNCATED AT 250 WORDS)     

平板运动试验前后Q—T离散度的半随机对照研究

为探讨冠心病患者运动试验后Q-T_d 改变的规律, 观察508例患者平板运动试验前后Q-T_d、Q-T_(cd)变化.结果显示:阳性组运动后1、3min Q-T_(cd)(3293±1090、31.01±11.09ms)比阴性组(28.91±10.03、27.00±10.08ms)显著延长(P<0.01,P<0.05);且比运动前(26.30±10.53ms)显著延长(P<0.05),认为Q-T_(cd)可作为冠心病运动试验的一项有价值的参数.