腹壁细粒棘球蚴病1例

腹壁细粒棘球蚴病较为罕见,本文报道了1例腹壁细粒棘球蚴病患者。该患者因发现腹部包块1年、伴包块皮肤破溃5 d,以“腹壁细粒棘球蚴病”收住入院,行腹壁下细粒棘球蚴病内囊摘除术,术后病理为细粒棘球蚴病（单房多子囊型）。本文旨在为腹壁细粒棘球蚴病临床诊断和治疗提供经验。     

复杂性肝棘球蚴病外科治疗策略研究进展

肝棘球蚴病是一种由棘球属绦虫幼虫所致的人畜共患性疾病。我国主要致病绦虫类型为细粒棘球绦虫和多房棘球绦虫,分别引起细粒棘球蚴病和多房棘球蚴病。目前,棘球蚴病治疗已经取得重大进展,但对于部分就诊时已出现一种或多种并发症以及病灶侵及肝门、重要血管及胆管的复杂性棘球蚴病病例的治疗仍存在一定困难。本文根据近年来文献报道,结合临床经验,对复杂性肝棘球蚴病的外科治疗策略进行综述。［关键词］     

西藏自治区棘球蚴病病例分析

目的了解西藏自治区棘球蚴病病例构成、地区分布及病灶分布情况。方法于2016年8-10月,采用分层整群抽样的方法,抽取西藏自治区7个地(市)70个县的364个行政村进行棘球蚴病流行情况调查,对居民进行B超检查,疑似病例辅以血清学检查,临床及疑似病例进行个案调查,影像学专家结合影像学和血清学检测结果及病例基本情况对病例进行确诊。采用SPSS 20.0统计学软件对数据进行统计分析。结果共B超检查77 049人,检出棘球蚴病病例1 230例,检出率为1.60%(1 230/77 049),其中细粒棘球蚴病占87.64%(1 078/1 230),多房棘球蚴病占11.06%(136/1 230),未分型病例占1.30%(16/1 230);全区7个地(市)均有细粒棘球蚴病和多房棘球蚴病病例检出,且不同地(市)、性别、年龄、民族、职业、文化程度、居住地生产类型等病例构成也均以细粒棘球蚴病为主。病例的文化程度以文盲为主,占71.95%(875/1 214),随着年龄的增长细粒棘球蚴病有明显的病例堆积现象;不同职业病例构成中,牧民细粒棘球蚴病病例百分比(91.02%)高于半农半牧民(87.78%)(χ~2=10.710,P0.05),不同生产类型病例构成中,牧区细粒棘球蚴病病例百分比(91.38%)高于农区(83.54%)(χ~2=9.008,P0.05)。棘球蚴病病例的病灶分布多在右肝,79%以上的病例仅有1个病灶。结论西藏自治区棘球蚴病病例以细粒棘球蚴病为主,牧区的牧民是防治的重点人群。     

抗细粒棘球绦虫疫苗的研究进展

细粒棘球蚴病是由细粒棘球蚴寄生引起的人兽共患寄生虫病,在全世界范围内流行,严重威胁经济发展和人民健康。犬是细粒棘球绦虫的终末宿主,牛、羊和人是细粒棘球蚴的中间宿主。目前针对棘球蚴病的药物和手术治疗效果尚不理想,疫苗作为预防和控制棘球蚴病传播的重要补充手段,研究尤为重要。本文对抗细粒棘球绦虫疫苗的研究进展进行综述,旨在为高效疫苗的进一步研制提供参考。     

细粒棘球蚴(Echinococcus granulosus)CO1与ND1基因序列分析

目的 为了明确内蒙古锡林郭勒盟西乌旗羊株和锡林浩特市人株细粒棘球蚴之间的基因型及其遗传变异情况。方法 利用分子生物学技术对采自两地区细粒棘球蚴的线粒体CO1基因与ND1基因进行了克隆和测序,并运用DNAStar5.0中的MegAlign工具对已测出的序列进行了分析。结果 西乌旗羊株细粒棘球蚴与锡林浩特市人株细粒棘球蚴CO1基因片段和ND1基因片段大小分别均为936 bp和895 bp。西乌旗羊株细粒棘球蚴CO1基因序列与新疆羊株细粒棘球蚴的CO1基因序列同源性为99.3%;锡林浩特市人株细粒棘球蚴CO1基因序列与新疆人株细粒棘球蚴的CO1基因序列同源性为98.6%;且西乌旗羊株和锡林浩特市人株细粒棘球蚴ND1基因与国内外已报道的G1型ND1基因序列完全相同。结论 表明内蒙古上述两地区细粒棘球蚴的同源性很高,且基因型均为G1型,这为内蒙古某些地区细粒棘球蚴流行虫株的确定提供了重要依据,同时也对当地细粒棘球蚴病的预防和控制具有重要意义。     

肾多囊型细粒棘球蚴病两例

肾细粒棘球蚴病较少见，据统计，至１９８１年，在新疆各地医院共收治的４５８１例细粒棘球蚴病病例中，本病仅３７例（占０．８％），且均为单囊型。今遇两例肾多囊型细粒棘球蚴病病例。例１，男性，６岁，维吾尔族，伊梨地区特克斯县农牧区学生，与犬和羊有密切接触史。...     

四川省甘孜藏族自治州棘球蚴病空间聚集性分析

目的分析四川省甘孜藏族自治州棘球蚴病空间分布情况及空间聚集区域,了解现阶段四川省甘孜藏族自治州棘球蚴病重点筛查地区,为四川省甘孜藏族自治州棘球蚴病防控工作提供参考。方法收集四川省甘孜藏族自治州18县325乡以2014年为主的棘球蚴病人群筛查数据,运用空间扫描统计量法、空间自相关法分析四川省甘孜藏族自治州细粒棘球蚴病和多房棘球蚴病检出率的空间聚集性,得到细粒棘球蚴病和多房棘球蚴病检出率分布的空间聚集区域。结果四川省甘孜藏族自治州细粒棘球蚴病空间分布呈现高检出率聚集,一级聚集区位于四川省甘孜藏族自治州西北部,一级聚集区内包含2个巢式聚集区,分别位于德格县东北部和石渠县东北部。多房棘球蚴病空间分布同样呈现高检出率聚集,一级聚集区与细粒棘球蚴病一级聚集区空间分布一致,一级聚集区内3个巢式聚集区分别位于德格县东北部、甘孜县北部和石渠县东北部。结论四川省甘孜藏族自治州棘球蚴病空间分布存在聚集性,通过空间聚集性分析可得到棘球蚴病空间聚集区域,即今后工作需要加强的区域。     

肝细粒棘球蚴病超声影象的病理基础探讨

对98例原发性肝细粒棘球蚴病人,149个肝包虫囊肿进行了超声影象学分型和组织病理学观察。结果表明,超声分型基本上可反映肝细粒棘球蚴囊肿发展阶段的病理特征,可看出随着患者年龄增长,包虫囊肿有由Ⅰ型至Ⅴ型转化的趋势。组织学观察表明,这一转化过程伴随着细粒棘球蚴囊肿自身损伤的逐渐加重。反映了肝细粒棘球蚴囊肿发生、发展和衰亡的规律。结果还表明,在肝细粒棘球蚴病例中,活力基本正常、损伤和死亡的囊肿约各占1/3。上述结果可供肝细粒棘球蚴病化疗中评价疗效时参考。     

细粒棘球绦虫病1例报告

<正> 细粒棘球绦虫(Echinococcus yranulosus),又名包生绦虫细粒棘球绦虫病(hydatidosis)。是由寄生在人体内的棘球蚴引起的。由于该虫发育缓慢,往往不出现急性发作症状,所以容易漏诊、误诊。现报道1例供参考。 患者潘某,女,26岁,因右上腹疼痛于1987年6     

细粒棘球蚴病疫苗的研制现状

细粒棘球蚴病是由细粒棘球蚴寄生引起的人兽共患寄生虫病,呈世界性流行,严重阻碍着畜牧业的发展和人体健康。目前细粒针对棘球蚴病的药物和手术治疗效果尚不理想,切断传播途径是有效的预防手段,预防性疫苗接种是预防细粒棘球蚴病的有效措施之一。使用潜在的家畜和犬类疫苗来对抗细粒棘球绦虫生命周期的幼虫和成虫阶段可能是生产强效疫苗的关键,而此类免疫疗法通常无法诱导足够的免疫反应。本文基于粗抗原或针对细粒棘球蚴的活疫苗、DNA疫苗、重组蛋白疫苗、系统疫苗学和/计算建模疫苗等的研究进展进行综述,为研发和改进下一代细粒棘球蚴疫苗提供理论参考。     

肝细粒和多房棘球蚴混合感染3例

目的探讨肝细粒和多房棘球蚴混合感染患者诊断及手术治疗,为该类患者临床诊治提供经验。方法回顾性分析2017-2018年青海省人民医院诊断为肝细粒和多房棘球蚴混合感染患者的临床资料。结果共确诊3例肝细粒和多房棘球蚴混合感染患者。其中1例经术前CT检查确诊为细粒和多房棘球蚴混合感染,并在术中得到证实;另2例经术前彩超及影像学检查诊断为细粒棘球蚴病,但根据术中病灶形态和术后病理学确诊为细粒和多房棘球蚴混合感染。2例患者行根治性手术治疗,1例探查后仅行肝细粒棘球蚴内囊摘除、外囊次全切除术。结论肝细粒和多房棘球蚴混合感染患者术前易漏诊、误诊,影像学检查联合术后组织病理学检查结果才能最终确诊。肝细粒和多房棘球蚴混合感染患者手术相对复杂、困难,针对不同感染类型患者应采取个体化手术治疗方案。     

肝囊型棘球蚴病术后腐蚀性硬化性胆管炎1例

腐蚀性硬化性胆管炎是一种肝囊型棘球蚴病术后罕见并发症,此类疾病虽罕见但病情进展迅速、缺乏有效治疗措施,病人往往预后较差。本文回顾性分析1例肝囊型棘球蚴病术后腐蚀性硬化性胆管炎患者诊疗过程,从而为腐蚀性硬化性胆管炎诊治提供参考。     

A Case of Isolated Cardiac Hydatid Cyst that Mimics Lymphoproliferative Malignancy

Cardiac cystic echinococcosis is a rare parasitic infestation caused by Echinococcus granulosus larvae and it composes 0.5–2% of all human cystic echinococcosis cases. The left ventricle is the most common affected area followed by right ventricle, interventricular septum, left atrium, right atrium, and interatrial septum. The diagnosis is difficult because of nonspecific clinical and radiographic findings. We present a case of isolated apical cardiac cystic echinococcosis mimicking lymphoproliferative disease.     

Splenic hydatidosis: a rare differential diagnosis in a cystic lesion of the spleen

Cystic tumours of the spleen are generally rare, and a parasitic origin is relatively unlikely. The present case report shows, however that when a splenic cyst is found, the differential diagnosis must always consider the possibility of echinococcosis. We report the case of a patient suffering from a cystic lesion of the spleen where surgery and histopathology yielded the diagnosis of splenic echinococcosis. Abdominal pain in the left upper quadrant and splenomegaly detected by simple abdominal radiology are the most commonly found indicators for this disease. The treatment should be surgical, attempting to preserve as much splenic tissue as possible, although conservative treatment is frequently unfeasable due to massive involvement of the spleen. Although rare, splenic hydatidosis should be included in the differential diagnosis when a cystic splenic lesion is identified with sonography or CT scan.     

Isolated Ruptured Inter‐Atrial Septal Cystic Echinococcosis during Pregnancy

Herein, we present a case of asymptomatic isolated cardiac cystic echinococcosis localized entirely to the inter‐atrial septum in a pregnant woman. The patient underwent successful surgery. Cardiac cystic echinococcosis is rarely seen in pregnancy. A high index of suspicion is necessary for the diagnosis of a cardiac cyst hydatid. The treatment of cardiac cyst hydatid is surgical and should not be delayed during pregnancy. Early surgery might prevent septic embolization and cardiac life‐threatening complications and save the lives of both mother and baby as in the present case.     

Hepatic cystic echinococcosis with specific CT findings

A hepatic central bisegmentectomy was performed on a 36-year-old Iranian man with suspected cystic echinococcosis. Hepatic computed tomography (CT) scan findings showed a large cystic lesion, which included many small round shaped cystic lesions. The diagnosis of hepatic cystic echinococcosis was confirmed during surgery. The aforementioned CT scan findings may be specific findings for cystic echinococcosis, in spite of a low appearance rate.     

An unusual presentation of hydatid cyst within the soft tissues of the back: re-investigation of the undiagnosed lung opacity

BACKGROUND: Echinococcosis is a zoonotic infection, affecting humans in a characteristic geographic distribution. The disease most commonly involves the liver and the lung and a soft tissue localization is very rare. METHODS: A case of a 68-year-old man, who presented with a cystic lesion on his back, which was presumed to be a lipoma or a sebaceous cyst. Surgical excision of the lesion was performed. RESULTS: Histopathology revealed a hydatid cyst and with further investigations, we identified the nature of a previously undiagnosed opacity in the right lung field. Although the patient previously presented with symptoms of hydatid cyst rupture (productive cough with haemoptysis), echinococcosis was not under consideration. CONCLUSIONS: This unusual case serves to demonstrate that echinococcosis, though rare, should be considered in the differential diagnosis of cystic lesions in every anatomic location, especially when they occur in endemic areas. We overview the diagnosis and treatment of this parasitic infection.     

原发性肝癌合并肝囊型棘球蚴病1例

本文报道1例原发性肝癌合并肝囊型棘球蚴病病例的诊治经过。患者因“间断性上腹部不适半月余”收治入院,行辅助检查提示原发性肝癌合并肝囊性棘球蚴病,行肝动脉灌注化疗栓塞术,囊型棘球蚴病病灶未处理,术后患者肝功能明显好转。     

囊型包虫病诊断抗原研究进展

国内外对应用免疫学方法诊断囊型包虫病作了广泛的研究,而合适抗原的应用是其成功的关键,因此,对囊型包虫病诊断抗原的研究受到高度关注.该文就囊型包虫病诊断抗原的研究进展作一综述.