我国关节镜外科被引最高的50篇文献分析

[目的]总结国内关节镜外科被引次数最高的50篇文献并分析其特征。研究我国关节镜外科具有高影响力的文献,进而为新生代关节镜外科医师推荐行业经典文献。[方法]利用计算机检索中国生物医学期刊引文数据库,以"关节镜"为关键词,检索结果依被引频次由高到低排序。纳入国内关节镜外科被引频次最高的50篇文献,排除不以关节镜为主要论述内容、护理类文献、脊柱内镜相关文献、同一时期病例重复的文献、会议报道等。对文献的标题、被引频次、发表时间、期刊来源、地区分布、机构来源、第一作者、文献类型和研究部位等进行统计分析。[结果]纳入的50篇文献被引跨度为246次到21次。全部文献发表在1994~2007年间,其中以2001年数量居首。分别发表在15本专业期刊,以《中华骨科杂志》发表最多(22篇),其次是《中国矫形外科杂志》(5篇),《中华创伤杂志》和《中华外科杂志》并列第3(4篇)。文献来自11个省、直辖市,上海(16篇)、北京(15篇)和辽宁(5篇)分别排名前3。文献发表自22所大学或医院,其中8个单位有2篇或2篇以上,以上海交通大学附属第六人民医院发表最多(7篇),其次是上海交通大学附属第九人民医院(6篇),解放军总医院、北京大学第三医院和大连医科大学附属第一医院并列第3(均为5篇)。共10位作者以第一作者身份发表2篇或2篇以上文献。临床研究共47篇,综述文献为3篇。其中关节镜技术用于膝关节文献最多(42篇),肩(2篇)、肘(1篇)、髋(1篇)、踝(1篇)关节的探索研究则相对较少。[结论]发表在行业顶级期刊,多产出于国内研究实力强劲的医院和行业内知名专家以及临床研究居多,是关节镜外科最高被引文献的主要特征。总结被引最高文献有助于了解我国关节镜外科研究的历史足迹并指导未来研究方向。     

1994至2004年我国关节置换外科被引率最高的50篇文献

目的筛选我国关节置换外科被引率最高的50篇文献并总结其主要特征,为关节置换外科青年医师提供经典文献阅读的参考。方法利用中国生物医学期刊引文数据库,以"关节、置换、成形、假体、重建"为关键词进行检索,时间范围设置为"1994年1月至2003年12月",筛选出我国关节置换外科被引最高的50篇文献。提取文献题目、被引次数、发表年份、期刊来源、地区分布、作者单位、第一作者姓名和文献类型等进行统计分析。结果被引最高的50篇文献被引频次从606次到24次。文献发表在1994年到2003年间,其中2003年最多(11篇)。这些文献刊登在15本专业期刊,以《中华骨科杂志》发表最多(25篇)。文献来自10个省市地区,排名前三的省市为北京(24篇)、上海(12篇)、广东和江苏(各3篇)。文献来源于28所机构,排名第一的是北京大学人民医院(10篇)。共4位作者以第一作者身份发表一篇以上文献。文献研究类别分类中,以临床效果研究(29篇)、围手术期处理(8篇)和综述(7篇)位居前三。结论被引最高文献的总结不仅有助于了解我国关节置换外科研究的历史特征,指导未来研究的方向,还可以为关节置换外科青年医师提供经典文献阅读的参考。     

2004至2013年我国关节置换外科被引最高的50篇文献

目的 筛选近10年我国关节置换外科被引最高的50篇文献并归纳其主要特征,为关节置换外科青年医师提供经典文献阅读的参考。方法 利用中国生物医学期刊引文数据库,以“关节、置换、成形、假体、重建”为关键词进行检索,时间范围设置为“2004年1月至2013年12月”,筛选出我国关节置换外科被引最高的50篇文献。提取文献题目、被引次数、发表年份、期刊来源、地区分布、作者单位、第一作者姓名和文献类型等进行统计分析。结果 被引最高的50篇文献被引频次从355次到21次。文献发表在2004年到2009年间,其中2004年最多(19篇)。这些文献刊登在19本专业期刊,以《中华骨科杂志》发表最多(11篇)。文献来自15个省市地区,排名前三的省市为北京(14篇)、广东(11篇)、上海(各7篇)。文献来源于39所机构,排名第一的是北京大学人民医院、中国人民解放军总医院、中日友好医院和浙江大学医学院附属第二医院(均3篇)。共4位作者参与发表两篇以上文献。文献研究类别分类中,以临床效果研究(33篇)、围手术期处理(7篇)和综述(6篇)位居前三。结论 被引最高文献的总结不仅有助于了解我国关节置换外科研究的发展情况,指导未来研究的方向,还可以为关节置换外科青年医师提供最新的高质量文献作为阅读时的参考。     

国内Ilizarov技术被引频次最高20篇文献的分析与启示

[目的]总结分析国内关于Ilizarov技术被引频次最高的20篇文献。了解目前Ilizarov技术在我国具有高关注度和影响力的内容,推荐该领域值得借鉴的经典文献。[方法]检索CNKI数据库、CMCC、万方数据资源系统、维普等经典中文数据库,分别以"Ilizarov、伊利扎诺夫、伊里扎诺夫、伊利扎洛夫、伊里扎洛夫、牵拉组织再生、牵拉成骨、微创牵拉、骨痂牵拉、骨搬移、骨滑移、骨段转移、肢体延长"为主题词,按照被引频次由高到低排序,去除交叉重叠文献,选择最高被引频次数据作为检索结果。对文献的被引频次、发表时间、主旨内容、发表期刊、文献来源区域、第一作者等统计分析。[结果]20篇文献被引频次从115次到21次。发表时间在1994~2010年间,其中以2004~2010年最多。文献内容涉及Ilizarov技术理论、基础及临床应用。发表在7本学术核心期刊,以《中国矫形外科杂志》最多(7篇),其次是《中华外科杂志》(4篇)和《中华骨科杂志》(4篇)。文献来自全国6个省市,除香港地区1篇外其余均来自北方地区,以北京最多(15篇)。第一作者13位,以秦泗河最多(7篇),其次是夏和桃(2篇),其余作者均为1篇。[结论]Ilizarov技术基础与理论关注度最高,其次是经典应用和适应证扩展。该技术在2010年前主要集中在北方医生应用,北京处于突出的主导地位。近年学习应用及研究的医生明显增多。检索结果有助于了解我国应用Ilizarov技术现状、相关医生在临床、学术的既往工作,作为中文经典文献推荐给致力于这项技术的医师和相关研究者。     

2000至2004年《中华骨科杂志》载文被引分析

目的从文献引证的角度了解《中华骨科杂志》的学术水平和期刊质量。方法以《中华骨科杂志》2000至2004年共60期刊载的论文和被引用的论文为研究对象。依据中国生物医学期刊引文数据库(ChineseMedicalCitationIndex,CMCI),采用文献计量学方法对载文被CMCI来源期刊引用的情况进行统计分析及评价。主要文献计量学统计指标为各年度发文被引比例、单篇论文平均被引次数、单篇论文被引情况、作者发文被引情况、被引论文的地区分布、高被引作者机构、被引论文年代分布、主要引用期刊和自引率。结果《中华骨科杂志》2000至2004年发表论文1184篇,被CMCI来源期刊引用了749篇(4213次),被引率分别为76.43%、75.20%、71.49%、57.46%和30.19%,平均被引率为63.26%,单篇论文被引次数分别为7.86、6.54、5.48、2.98和1.78次,平均被引次数为5.62次,单篇被引最高次数为68次。被引作者群的地域分布30个省(自治区)、直辖市和特区。北京、上海和天津在骨科学研究领域居于国内前列。CMCI来源期刊中有461种期刊引用《中华骨科杂志》。《中华骨科杂志》自引191条,自引率为0.045。结论《中华骨科杂志》所载文献质量较高,是我国骨科学研究领域最重要的信息源之一,也是我国医学领域的主要核心期刊。     

2005至2009年《中华骨科杂志》载文被引分析

目的 从文献引证的角度透视<中华骨科杂志>的学术水平和期刊质量.方法 利用<中国生物医学期刊引文数据库>(chinese medical citation index,CMCI),采用文献计量方法对<中华骨科杂志>载文被CMCI来源期刊引用的情况进行统计分析,主要文献计量学统计指标包括各年度发文被引率、篇均论文被引次数、单篇论文被引情况、作者被引情况、被引作者的地区和高产机构分布、主要引用期刊和自引率及被引论文年代分布等.结果 2005至2009年<中华骨科杂志>发表论文1182篇,被引用了663篇(3728次),平均发文被引比例为56.09%,单篇论文平均被引5.62次,单篇论文最高被引为104次.单篇被引5次以上论文210篇,共被引2835次,占总被引篇数的31.68%,占被引总频次的76.04%.663篇被引论文中,共有国内外作者485人,作者最高被引篇数为12篇,被引1篇的作者386人,占作者总数的79.58%.被引作者群的地域分布30个省(自治区)、直辖市和香港、台湾地区及美国、加拿大、法国.北京、上海和天津在骨科学研究领域居于国内前列,其中北京居第一位,占32.16%.有445种期刊引用<中华骨科杂志>.<中华骨科杂志>自引217条,自引率为0.058.结论 <中华骨科杂志>所载文献质量高,在我国医学研究领域已具有较强的影响力,是骨科先进科研成果交流的平台.     

2005至2009年《中华骨科杂志》载文被引分析

目的 从文献引证的角度透视<中华骨科杂志>的学术水平和期刊质量.方法 利用<中国生物医学期刊引文数据库>(chinese medical citation index,CMCI),采用文献计量方法对<中华骨科杂志>载文被CMCI来源期刊引用的情况进行统计分析,主要文献计量学统计指标包括各年度发文被引率、篇均论文被引次数、单篇论文被引情况、作者被引情况、被引作者的地区和高产机构分布、主要引用期刊和自引率及被引论文年代分布等.结果 2005至2009年<中华骨科杂志>发表论文1182篇,被引用了663篇(3728次),平均发文被引比例为56.09%,单篇论文平均被引5.62次,单篇论文最高被引为104次.单篇被引5次以上论文210篇,共被引2835次,占总被引篇数的31.68%,占被引总频次的76.04%.663篇被引论文中,共有国内外作者485人,作者最高被引篇数为12篇,被引1篇的作者386人,占作者总数的79.58%.被引作者群的地域分布30个省(自治区)、直辖市和香港、台湾地区及美国、加拿大、法国.北京、上海和天津在骨科学研究领域居于国内前列,其中北京居第一位,占32.16%.有445种期刊引用<中华骨科杂志>.<中华骨科杂志>自引217条,自引率为0.058.结论 <中华骨科杂志>所载文献质量高,在我国医学研究领域已具有较强的影响力,是骨科先进科研成果交流的平台.     

重症肌无力外科治疗领域前100篇高被引论文的文献计量学分析

目的 分析重症肌无力外科治疗领域的研究热点和最新进展。方法 检索Web of Science数据库，纳入重症肌无力外科治疗领域被引频次最高的前100篇文献，并进行文献计量学分析。结果 被引频次最高的100篇文献的发表年份为1939—2021年，单篇被引频次为55～850次。纳入的文献大多为论著类文献（75/100），主要是回顾性研究（64/75）。美国是发表文献及被引频次最多的国家，Annals of Thoracic Surgery是发表文献最多的期刊（20篇）。通过VOSviewer软件分析，高密度关键词主要为thymectomy、maximal thymectomy、extended thymectomy、transcervical thymectomy、thymoma及autoantibodies。结论 手术切除范围、手术入路以及发病机制是目前重症肌无力外科治疗领域的热点。希望本文能够为今后该领域研究的开展提供参考。     

骨细胞力学信号转导功能研究被引最高50篇相关文献分析

目的本文拟分析和研究骨细胞受机械应力刺激相关方面被引率最高的50篇文献的基本特征,为临床相关研究提供一定的参考。方法计算机检索"Pubmed","Web of Science"等英文数据库,以"Compressive stress,Tensile stress,Fluid shear stress,stretch stress,centrifugal force,Micropipette stimulation,Electromagnetic force mode,Mechanical stress,mechanotransduction"和"osteocyte,osteoblast"为关键词进行检索,筛选出被引频次最高的50篇文献,排除与该研究不相关的其他文献,对文献的标题、第一作者、发表年份、期刊来源、地区分布、作者单位、被引频次等重要信息进行统计分析。结果被引最高的50篇文献的频次从239次到20次,发表于1999年至2015年,其中以2009年最多为9篇,文献刊登于27本期刊,其中以《Journal of Bone and Mineral Research》发表最多(11篇),其次是《Journal of Biological Chemistry》(6篇)、《Bone》(5篇);来源于12个国家,其中美国最多(21篇),发表2篇及2篇以上文献的大学或医院有7家,排名前两名的为印第安纳大学(4篇)、上海交通大学(3篇),共两位作者发表2篇以上文献,研究最多的信号通路依次为MAPK-ERK signaling pathway(11)篇、Wnt/beta-catenin signaling(9篇)、PI3K/AKT signaling pathway(4篇)、BMP signaling pathway(2篇)。结论被引最高文献的分析不仅有助于了解骨细胞机械应力刺激相关研究的发展状况,指导未来研究方向,还可以为广大研究者阅读文献提供参考。     

《中华整形外科杂志》2001-2005年论文被引分析

目的从文献引证角度透视《中华整形外科杂志》的办刊水平和期刊的编辑特点。方法依据CNKI《中国引文数据库》,采用文献计量学方法对《中华整形外科杂志》2001至2005年载文被CNKI源数据库文献引用情况进行统计分析和评价。结果2001至2005年《中华整形外科杂志》共载文1045篇,被CNKI引用530篇,占载文的50.72%;这些论文被引用1598频次,单篇平均被引3.02次。引用该刊的有289种期刊,他引率为92.43%,自引率为7.57%。被引论文作者群遍布国内25个省及直辖市,北京、上海、陕西和广东,在整形外科学研究领域居于前列。结论《中华整形外科杂志》所载文献质量较高,发表的论文能够反映整形外科学的发展和最新研究动态。该刊不仅是国内整形外科学研究领域最重要的信息源之一,也是国内医学领域的主要核心期刊之一。     

Reduction of Plasma Fibrinogen, Immunoglobulin G, and Immunoglobulin M Concentrations by Immunoadsorption Therapy with Tryptophan and Phenylalanine Adsorbents

Abstract Immunoadsorption (1A) therapy with tryptophan (TR-350) or phenylalanine (PH-350) adsorbents has been used to reduce the concentration of serum antibodies in human lymphocyte antigen (HLA)-immunized patients. Other forms of plasma purification have been reported to reduce the level of fibrinogen, which affects the blood properties. In this study we investigated the effects of IA therapy using both adsorbents on plasma fibrinogen and immunoglobulins G and M in 13 patients (8 patients were treated with TR-350, and 5 patients were treated with PH-350). During each session 1 plasma volume (2.8 ± 0.4 L of plasma) was processed through the immunocolumn and then returned to the patient together with the blood cells. Compared with the pretreatment values, the plasma fibrinogen, IgG, and IgM concentrations were significantly reduced after IA therapy (p < 0.01 for TR-350; p < 0.04 for PH-350). There was a positive correlation between the degree of reduction of plasma proteins and the number of IA treatments given. A nonpara-metric test (Wilcoxon's signed-rank test or the Mann-Whitney test) was used for statistical analysis. We conclude from our study that IA therapy effectively lowers the plasma levels of fibrinogen, IgG, and IgM and thus can be considered a valuable alternative to other blood purification methods.     

Is the recovery profile of mivacurium independent of the rate of decay of its plasma concentration in patients with normal plasma cholinesterase activity?

Background: The duration of action of muscle relaxants is poorly correlated to the rate of decay of their plasma concentration. The plasma concentration of mivacurium may rapidly decrease below its active concentration because of the extensive hydrolysis of mivacurium. By inflating a tourniquet on one upper limb for 3 min after the administration of atracurium, mivacurium or vecuronium, we studied the influence of the initial decline of their plasma concentration on their effect. Methods: In 50 patients anaesthetised with thiopental, isoflurane and fentanyl, the effect of bolus doses of 0.15 or 0.25 mg . kg^?1 mivacurium (MIV 15, MIV 25), 0.3 or 0.5 mg . kg^?1 atracurium (ATR 30, ATR 50) and 0.06 or 0.1 mg . kg^?1 vecuronium (VEC 06, VEC 10) were measured on both arms (evoked response of the adductor pollicis to train-of-four stimulation every 12 s), a tourniquet being applied on one arm just before and during 3 min after the muscle relaxant bolus. Results: Tourniquet inflation of 3 min almost abolished the neuromuscular effect of mivacurium. In the vecuronium groups and in the ATR 50 group, tourniquet inflation did not modify the maximum degree of depression of the twitch response. Also, the duration of action of vecuronium was unaffected by the tourniquet. In the ATR 30 group, times to return of the twitch response to 25% (duration 25%) and 75% (duration 75%) of control response were significantly shorter in the cuffed arm, 23 min vs 27 min, and 41 min vs 45 min, respectively. In the ATR 50 group, only duration 25% was significantly shorter in the cuffed arm (41 min vs 45 min). Conclusion: The results suggest that the rate of decline of the plasma concentration of mivacurium is so rapid, that a very low and almost clinically ineffective concentration is present as soon as 3 min after its administration. The results also indicate that the recovery from a mivacurium-induced neuromuscular blockade is not influenced by the rate of decay of its plasma concentration in patients with genotypically normal plasma cholinesterase.     

Membranes in Artificial Organs

Abstract: Membrane processes play a pivotal and enabling role in modern replacement therapy for acute and chronic organ failure and in the management of immunologic diseases. In fact, virtually all contemporary extracorporeal blood purification methods employ membrane devices, and the next generation of artificial organs and tissue engineering therapies are almost certain to be similarly grounded in membrane technology. In this short essay, we comment on the similarities and differences among synthetic membranes and their natural counterparts and also provide a critical overview of the demographics and technology of hemodialysis, hemofiltration, apheresis, oxygenation, and emerging membrane technologies and applications.     

The multiply injured child

Blunt trauma is the principal cause of childhood death in many developed countries. This review outlines the differences between adults and children with respect to resuscitation and treatment of orthopaedic injuries in a child with polytrauma. Recent advances in techniques of fracture stabilization are reported.     

Dilemma of Membrane Biocompatibility and Reuse

Abstract: Numerous articles have been published on the multiple use of dialyzers and on the effect of different reprocessing chemicals and techniques on the dialyzer biocompatibility and performance. The results often appear contradictory, especially those comparing standard biocompatibility parameters. Despite this confusion, a discerning review of the published works allows certain limited conclusions to be drawn. Reprocessing of used hemodialyzers changes the biocompatibility profile of a dialyzer as defined by the parameters complement activation. leukopenia, and cytokine release. The effect of reprocessing depends on the chemicals and reprocessing technique applied and also on the type of membrane polymer being subjected to the reprocessing procedure. Reports of pyrogenic reactions indicate that the flux of the membrane also influences how suitable it is for safe reuse. An increased risk of allergic and pyrogenic reactions appears to be associated with dialyzer reuse. Furthermore, there has been a lack of investigations into the immunologic effect of the layer of adsorbed and chemically altered proteins that remains on the inner surface of reprocessed dialyzers. We conclude that the clinical benefit of dialyzer reuse cannot be generally accepted from a biocompatibility point of view.     

The analgesic effect of racemic ketamine in patients with chronic ischemic pain due to lower extremity arteriosclerosis obliterans

Background : Ketamine in sub-dissociative doses has been shown to have analgesic and phantom-Limb pain, where conventional treatment has often failed. Chronic ischemic pain due to lower extremity arteriosclerosis obliterans often responds poorly to analgesics, and the pain-generating mechanisms are not well understood.
Methods : Eight patients with rest pain in the lower extremity due to arteriosclerosis obliterans were given sub-dissociative doses of 0.15, 0.30, or 0.45 mg/kg racemic ketamine and morphine 10 mg as a 5-min infusion on four separate days in a cross-over, double-blind, randomised protocol. Plasma levels of (S)- and (R)-ketamine and their nor-metabolites were analysed with an enantioselective high-performance liquid chromatography (HPLC) method. Pain levels were evaluated with a visual analogue scale (VAS).
Results : Individual pain levels were highly variable during and after all the infusions but the pooled pain levels showed a dose-dependent analgesic effect of ketamine with a transient but complete pain relief in all patients at the highest dose (0.45 mg/ kg). Side-effects, mainly disturbed cognition and perception, were pronounced and dose-dependent. Morphine 10 mg had an analgesic peak at 20 min and 5/8 patients had complete pain relief. The remaining 3 patients also had high baseline pain scores, indicating a higher analgesic potency for the 0.30 and 0.45 mg/ kg ketamine doses than for morphine 10 mg.
Conclusion : We have demonstrated a potent dose-dependent analgesic effect of racemic ketamine in clinical ischemic pain. Due to a narrow therapeutic window, this analgesic effect is probably best utilised in combination with other analgesics.     

Intravenous endotoxin does not increase tissue extravasation of albumin in rats

Background : It is unclear whether activation of the inducible nitric oxide synthase (iNOS) increases or decreases the extravasation of plasma.
Methods : Chloralose anaesthetised male Wistar rats received E. coli lipopolysacharide (LPS), 3 mg kg^-1 i.v., or the corresponding volume of saline, 3 or 5 h before the end of the experiment. Mean arterial pressure (MAP) and heart rate (HR) were recorded. Tissue clearance of radio-labelled albumin, during the last 2 h of each experiment, was determined by a double-isotope method. In separate animals, the serum concentration of nitrite and nitrate was determined, 5 h after LPS or the solvent.
Main Results : LPS initially decreased MAP and lastingly increased HR. In the 3-h LPS animals (n=8), tissue plasma clearance was lower in the heart and calf muscle and increased only in diaphragm, compared to corresponding control animals (n=8). In the 5-h LPS rats, clearance was lowered (n=8) in the entire gastrointestinal tract and in testes, compared to controls (n=8). The serum nitrite/nitrate concentration was higher in animals given LPS (n=6) than in controls (n=6).
Conclusion : After LPS, tissue clearance of albumin was not increased in any major tissue, in spite of increased serum levels of NO end products. Apparently, after activation of iNOS, the augmented release of NO is not necessarily associated with increased albumin extravasation.     

Adrenaline markedly improves thoracic epidural analgesia produced by a low-dose infusion of bupivacaine, fentanyl and adrenaline after major surgery: A randomised, double-blind, cross-over study with and without adrenaline

Background: Basic pharmacological research indicates that there are synergistic antinociceptive effects at the spinal cord level between adrenaline, fentanyl and bupivacaine. Our clinical experience with such a mixture in a thoracic epidural infusion after major surgery confirms this. The objectives of the present study were to evaluate the effects on postoperative pain intensity, pain relief and side effects when removing adrenaline from this triple epidural mixture. Methods: A prospective, randomised, double-blind, cross-over study was carried out in 24 patients after major thoracic or abdominal surgery. Patients with only mild pain when coughing during a titrated thoracic epidural infusion of about 10 ml · h^?1 of bupivacaine 1 mg · ml^?1, fentanyl 2 μg · ml^?1, and adrenaline 2 μg · ml^?1 were included. On the 1^st and 2^nd postoperative days each patient was given a double-blind epidural infusion, at the same rate, with or without adrenaline. The effect was observed for 4 h or until pain when coughing became unacceptable in spite of a rescue analgesic procedure. Rescue analgesia consisted of up to two epidural bolus injections per hour and i.v. morphine if necessary. All patients received rectal paracetamol 1 g, every 8 h. Fentanyl serum concentrations were measured with a radioimmunoassay technique at the start and end of each study period. Main outcome measures were extent of sensory blockade and pain intensity at rest and when coughing, evaluated by a visual analogue scale, a verbal categorical rating scale, the Prince Henry Hospital pain score, and an overall quality of pain relief score. Results: The number of hypaesthetic dermatomal segments decreased (P <0.001) and pain intensity at rest and when coughing increased (P <0.001) when adrenaline was omitted from the triple epidural mixture. This change started within the first hour after removing adrenaline. After 3 h pain intensity when coughing had increased to unacceptable levels in spite of rescue analgesia (epidural bolus injections and i.v. morphine). Within 15–20 min after restarting the triple epidural mixture with adrenaline, pain intensity was again reduced to mild pain when coughing. Serum concentration of fentanyl doubled from 0.22 to 0.45 ng · ml^?1 (P <0.01), and there was more sedation during the period without adrenaline. Conclusions: Adrenaline increases sensory block and improves the pain-relieving effect of a mixture of bupivacaine and fentanyl infused epidurally at a thoracic level after major thoracic or abdominal surgery. Serum fentanyl concentrations doubled and sedation increased when adrenaline was removed from the epidural infusion, indicating more rapid vascular absorption and systemic effects of fentanyl.