毛囊显微移植技术治疗秃顶──附565例临床分析

目的　观察毛囊显微移植治疗秃顶的临床效果。方法　通过毛囊显微移植技术治疗各种秃顶脱发 5 6 5例 ,随访时间平均 1年 (8～ 14个月 )。结果　术后平均 2～ 3个月长出头发 ,5～ 6个月达到初步视觉效果。 5 6 5例手术中 ,男女性正常脱发及眉毛移植的毛囊存活率为 95 %～ 10 0 % ,瘢痕毛囊移植存活率达 90 %以上 ,头发生长速度、发质粗细度均保持了供发区毛发的特性。结论　该手术时间短 ,恢复快 ,经过 3年临床观察 ,该技术在中国人群中能达到良好的效果。     

单株自体毛发移植加密修饰睫毛

目的 探索应用单株自体毛发移植修饰睫毛短而稀疏的效果.方法 对26例女性求美者,采用枕后安全区头皮,制成毛干长4 cm的单株移植物,用缝合针将头发移植到上睑缘处,每侧30～40根.结果 植入毛发生长良好,方向、形态满意,使用电睫毛夹夹烫或睫毛膏修饰,效果更佳,移植毛发成活率在95%以上.结论 单株自体毛发移植加密修饰睫毛是一种适宜的睫毛修饰方法.

Abstract：

Objective To explore the aesthetic result of dense-packing single-hair grafting for eyelash. Methods Twenty-six female cases were treated with the donor sites at the occipital safe area.The single-hair grafts were made with the hair of 4cm in length. The grafts were transplanted to the upper lid margin with needle technique, 30-40 grafts at each side. Results The hair grafts survived very well with good growth direction. It looked even better when it had a permanent wave or the mascara was applied.The survival rate of hair grafts was more than 95%. Conclusions It is feasible to improve the shorter and thinner eyelash by dense-packing single-hair grafts.     

自体单株毛囊种植修复上唇胡须缺损

目的:探索应用自体单株毛囊移植修复上唇胡须缺损的效果。方法:对17例患者采用切取枕后安全区头皮条的方法或利用直径8mm的电动环钻获取毛发移植物,在3倍放大镜下制成单株移植物,并利用21或22G注射器针头穿刺打孔,然后用显微镊夹持毛干部,将毛发移植到缺损处以修复形态。结果:植入毛发生长良好,形态满意,移植毛发成活率在95%以上。结论:单株自体毛囊种植修复胡须缺损是一个适宜的方法。     

毛发移植修复外伤后眉缺损的临床观察

目的 观察因外伤、烧伤等致眉毛缺损的患者,采用自体单株毛囊种植修复的临床效果.方法 对73例因外伤或烧伤造成眉弓区瘢痕,或经游离皮肤移植及皮瓣、扩张皮瓣修复后致眉毛缺损的患者,根据所需移植物大小,相应地选用21 G或22 G注射器针头穿刺打孔,在针头退出的同时,用显微镊植入制备好的单株毛囊,修复其形态.结果 本组共73例患者,其中4例术后出现毛囊炎,经用75％乙醇涂擦后痊愈.其余患者的植入毛发生长良好,方向及形态满意,成活率在90％以上.结论 对于外伤、烧伤后致眉缺损的患者,采用自体单株毛囊种植修复技术,虽然在操作上有一定难度,但仍以毛发移植修复为宜;对于眉弓区软组织条件不适合进行眉毛种植的患者,可以针对其原因进行治疗,然后采用毛发移植修复缺损,也能获得良好的效果.     

针头打孔自体单株毛囊种植修复眉缺损

目的 探讨用注射器针头打孔自体单株头发毛囊种植修复眉缺损的效果.方法 对52例(双侧眉缺损35例,单侧缺损17例,共计87条眉毛)因烧伤、外伤、手术切除、眉修饰不当等原因造成的眉缺损患者,采用切取枕后头发安全供区或颞部头皮条的方法,在3倍放大镜下制成毛干长1～2 cm的单株移植物,并利用21G或22G注射器针头穿刺打孔,然后用显微镊夹持毛干部,将头发移植至眉缺损部位修复其形态.结果 术后2例烧伤后患者出现毛囊炎,经75％乙醇涂擦治疗后痊愈.其余植入头发生长良好,方向、形态满意,成活率在90％以上.结论 利用针头打孔,显微镊夹持毛干,移植自体单株毛囊种植修复眉缺损,操作方便,效果良好.     

毛发诱导结合自体毛囊单位移植技术进行毛发定向重建的研究

目的 将异位诱导形成的毛发组织进行移植,实现毛发的定向重建.方法 制备新生C57鼠的皮肤细胞悬液注射于裸鼠体内,诱导形成皮下异位毛发组织,取出后在体视显微镜下分离成单个毛囊单位,移植至裸鼠体表,并进行大体观察和组织学检测.结果 按照预定密度移植后的毛发成活良好并呈周期性生长,组织学可见各时期相应的毛囊形态.结论 诱导形成的毛发组织可以作为移植物,通过毛囊单位移植的方式,实现毛发组织密度和方向的可控性重建.     

富血小板纤维蛋白辅助毛囊移植修复毛发缺失的应用研究

为探讨富血小板纤维蛋白辅助毛囊移植对毛发缺失进行修复的临床应用效果，本研究选取 2020年1月-2022年1月我院收治的30例毛发缺失患者，观察其临床治疗效果和毛囊存活情况。结果显示， 所有患者的治疗优良率及毛囊存活率分别为83.33%、92.00%。说明对脱发患者进行高密式毛发移植联合 PRF治疗的临床效果确切，毛囊存活率高，值得临床应用。     

自体单株毛发移植修复女先天性无阴毛或阴毛发育不良

目的探索应用自体毛发单株移植修复女先天性无阴毛或阴毛发育不良的效果。方法对12例成年女性患者,均采用切取枕后区包含全厚皮肤与完整毛囊的条形头皮组织,在手术放大镜下,将头皮条全部分割成1个个单株毛发备用。用规格为0．9mm×38．0mm的针头穿刺打孔,将单株毛发移植到外阴部以增补稀疏的阴毛和扩大分布面积,每例移植400700个单株毛发,阴毛分布形态多选用倒三角形或菱形,密度为阴阜部阴毛按20株／cm^2植入,然后向外扩散密度逐步减小,最少不低于10株／cm^2。结果随访9个月至2年,植人毛发生长良好,阴毛形态及方向和分布范围均与正常接近一致,效果满意。均1次手术成功无需进行2次加密治疗,枕后供区切口瘢痕不明显。结论用毛发移植术补足阴毛,方法简便,创伤小,外形自然美观,是目前补充阴毛不足或无阴毛的理想方法。     

自体毛发移植术治疗脂溢性脱发3000例

目的：探讨和分析运用自体毛发移植术治疗脂溢性脱发的效果和特点。方法：对3000例脂溢性脱发的患者运用自体毛发移植术进行修复。结果：移植的头发均生长良好，但因每个人脱发面积不同、供发区头发密度不同，移植后头发生长密度不同。结论：自体毛发移植术可以运用于脂溢性脱发的修复，移植时，要按自身的特点及需要设计不同的发际线；按自身头发的正常生长方向移植；移植后的头发随周围正常头发的生长而生长；因脱发面积的不同及供发区头发密度的不同，移植后头发生长密度不同。     

800 nm Lightsheer半导体激光脱毛临床疗效及组织病理变化

目的通过观察中国人脱毛的临床疗效及治疗前后的组织病理改变,探讨Lightsheer半导体激光脱毛的机制,探索出中国人的最佳治疗参数。方法应用Lightsheer半导体激光仪(波长800 nm,脉宽100 ms,光斑面积为9 mm×9 mm)对80例脱毛者进行脱毛治疗,能量密度20～40 J/cm~2,2次治疗间隔为1个月。应用毛发平均直径及毛发平均密度定量观察临床疗效,光镜及电镜下观察脱毛前后毛发、毛囊及其他皮肤结构的组织病理改变。结果80例经过3次脱毛治疗后,治疗区域毛发数量显著减少,剩余少许新生毛发直径变细。光镜下见毛囊有损伤,电镜下见整个毛囊壁均有不同程度损伤,内外毛根鞘细胞,特别是毛球部的毛母质细胞胞质内发生空泡样改变,内质网明显扩张,线粒体肿胀,细胞内含有的黑素小体崩解等改变。结论Lightsheer半导体激光采用适当能量密度进行脱毛治疗,能有效而安全地脱去毛发。     

应用小室模型再生毛发的实验研究

目的 建立毛囊重建小室模型,并应用该模型进行毛发再生实验研究。方法 制备小室模型,分离C57BL/6新生小鼠的表皮和真皮细胞,混合后注入小室内。7 d后拆除小室,并观察创口部位的毛发再生情况。30 d后对创口部位皮肤取材,行HE染色,观察其形态结构。结果 裸鼠小室植入部位创面愈合并可见毛发再生,新生毛发大体观和镜下观与正常毛发无明显差异,且排列极性、生长密度良好。对部分无毛发再生的创面进行分析,发现模型构建过程中小室植入的位置对毛囊再生具有重要的影响。结论 应用小室模型和新生鼠表皮真皮细胞可以成功实现毛发再生,小室模型是一种可用于毛囊再生研究的良好动物模型,且小室的植入位置对该模型的成功与否具有重要影响。     

Hair tourniquet syndrome: revisited

Hair tourniquet syndrome is a rare condition. It is an important emergency condition where urgent attention is needed. In this condition, body appendages are strangulated by hair that acts like a tourniquet. A strand or strands of hair act like a circumferential constriction band and subsequently strangulate the body appendages. Commonly affected sites include fingers, toes or even genitals. Failure to identify and release the acute constriction may result in amputation of affected body part. We report two cases of hair tourniquet syndrome of the thumb and toe that were successfully released without complications.     

超级脱毛模式的临床效果观察

目的 探讨超级脱毛模式（super hair remoral,SHR）的临床效果及耐受程度.方法 采用SHR对发际、面颊、上唇、胡须、胸腹、乳晕周围、腋窝、四肢及比基尼邻近区等共进行了1 000个部位的脱毛;对一些疼痛特别敏感的部位,如上唇及头面部,治疗时采用复方利多卡因乳膏外涂1 h以上.结果 四肢、胸腹、背部及腋窝部位的毛发,一般需要4～5次治疗方可达到根治目的 ,且美容就医者无明显不适感;上唇、下颌周围毛发一般需要5～7次治疗方可收到满意效果,且需要外涂麻药,否则部分美容就医者会呈现不适感.结论 SHR模式与传统脱毛方式、光子脱毛及其他激光脱毛方式相比,具有有效性高、脱毛速度快、耐受性强等优点,值得推广.     

Method of tying up hair during hair transplantation

We have reported on a simple and secure method of tying up hair during transplantation surgery for alopecia. The implements used were Kocher's forceps and rubber bands which are readily obtainable in the operating theater.     

Ruby laser-assisted hair removal – correlation of efficacy with the growth cycle of human hair

There is great variation in response when ruby laser is used to remove unwanted body hair. Destruction of hair is often not possible after one laser treatment and the frequency and timing of repeated treatments required to achieve optimum treatment results are unknown. It was the aim of this study to determine whether the efficacy of ruby laser hair removal depended on the hair growth cycle. A prospective clinical study was carried out. The lower legs of 48 patients were treated with the Chromos 694 ruby laser at a standard fluence of 11 Jcm^–2. Treatment efficacy was determined as the percentage decrease in hair density at 3 and 7 months. The proportion of growing and resting hairs in the treatment site was assessed by examination of plucked hair roots harvested from areas adjacent to the treatment site. To determine whether examination of plucked hair roots microscopically was reliable in assessing the proportion of growing and resting hairs in a specific site, 7 ex-vivo scalp skins were examined histologically. Results showed that examination of plucked hair roots was a reliable method in assessing the proportion of growing and resting hair. There was no correlation between the treatment efficacy and the growth phases of hair (one way analysis of variance, P=0.116). In conclusion, growing hairs are not more susceptible than resting hairs to ruby laser injury. The clinical implications of this finding are discussed. Received: 14 November 1998 / Accepted: 4 December 1999     

Hair fixation in rhytidectomy

A simple and useful way for effective fixation of hair during the entire length of rhytidectomy is proposed. This is achieved by gathering the whole scalp of hair into bundles by means of simple rubber bands, which permit lengthy surgery without the interference of hair in the operative field.