α1-receptor blockers combined with acupuncture treatment efficacy analysis of elderly patients with acute urinary retention

Objective To explore acupuncture and al-receptor blocker treatment efficacy of elderly patients with acute urinary retention. Methods Use of forward-looking monitoring and retrospective survey methodology, Choose January 1,2006 to January 1,2009 of acute urinary retention in 82 cases of elderly inpatients,Chronological order according to treatment group,39 cases were divided into control group,43 cases; Transurethral catheterization in both groups, stay catheter. The control group was treated with α1-receptor blocker hytrin (terazosin) and the application of antibiotics; the treatment group based on the above plus acupuncture therapy. Results The treatment group was 94.87% in the control group response rate was 76.74%, the two groups,P<0.05, the difference was significant. Conclusion al-receptor blockers combined with acupuncture treatment of elderly patients with acute urinary retention al-receptor blocker than simply good effects, synergistic effect, shortening the indwelling catheter time, avoid repeated urinary catheterization and reduce hospital infection, worthy to be popularized.     

依达拉奉对急性大面积脑梗死患者高敏C反应蛋白影响的临床研究

Objective To explore the effects of edaravone on high sensitivity C-reaction protein (hsCRP) in patients with acute massive cerebral infarction. Methods 86 cases with acute massive cerebral infarction were selected from December 2006 to December 2008. all the cases were divided into two groups, control group and cure group. routine treatment was used to the control group, on the basis of control group'therapy,edaravone was given to cure group. the level of hsCRP was detected before and after treatment, and the results of cure was compared. Results ①the total effective rate in two groups existed statistical difference (P<0.05);② the level of hsCRP in two groups before treatment and in the 7th and the 14th of treatment existed statistical difference(P<0.01), the level of hsCRP in the 7th and the 14th of treatment in cure group existed statistical difference(P<0.05). Conclusion Edaravone can decrease the level of hsCRP in patients with massive cerebral infarction, and has significant clinical efficacy,which should be the reference for the doctors.     

依达拉奉对急性大面积脑梗死患者高敏C反应蛋白影响的临床研究

Objective To explore the effects of edaravone on high sensitivity C-reaction protein (hsCRP) in patients with acute massive cerebral infarction. Methods 86 cases with acute massive cerebral infarction were selected from December 2006 to December 2008. all the cases were divided into two groups, control group and cure group. routine treatment was used to the control group, on the basis of control group'therapy,edaravone was given to cure group. the level of hsCRP was detected before and after treatment, and the results of cure was compared. Results ①the total effective rate in two groups existed statistical difference (P<0.05);② the level of hsCRP in two groups before treatment and in the 7th and the 14th of treatment existed statistical difference(P<0.01), the level of hsCRP in the 7th and the 14th of treatment in cure group existed statistical difference(P<0.05). Conclusion Edaravone can decrease the level of hsCRP in patients with massive cerebral infarction, and has significant clinical efficacy,which should be the reference for the doctors.     

Removal of biofilm is essential for long-term ventilation tube retention

BACKGROUND Although long-term retention of a ventilation tube is required in many ear diseases,spontaneous removal of conventional ventilation tube is observed in patients within 3 to 12 mo.To address this issue,we aimed to determine a new method for long-term retention of the ventilation tube.AIM To explore the value of removing the biofilm for long-term retention of tympanostomy ventilation tubes.METHODS A case-control study design was used to evaluate the safety and effectiveness of long-term tube retention by directly removing the biofilm(via surgical exfoliation)in patients who underwent myringotomy with ventilation tube placement.The patients were randomly divided into two groups:Control group and treatment group.Patients in the treatment group underwent regular biofilm exfoliation surgery in the clinic,whereas those in the control group did not have their biofilm removed.Only conventional ventilation tubes were placed in this study.Outcome measures were tube position and patency.Tube retention time and any complications were documented.RESULTS Eight patients with biofilm removal and eight patients without biofilm removal as a control group were enrolled in the study.The tympanostomy tube retention time was significantly longer in the treatment group(43.5±26.4 mo)than in the control group(9.5±6.9 mo)(P=0.003).More tympanostomy tubes were found to be patent and in correct position in the treatment group during the follow-up intervals than in the control group(P=0.01).CONCLUSION Despite the use of short-term ventilation tubes,direct biofilm removal can be a well-tolerated and effective treatment for long-term tube retention of tympanostomy ventilation tubes in patients who underwent myringotomy.     

拔尿管前行膀胱冲洗对开颅术后患者的影响

Objective To discuss the influence of bladder irrigation before pulling out catheter on the patients after craniotomy. Methods One hundred conscious patients after craniotomy were randomized into the experimental group and control group, each with 50cases. The experimental group was given bladder irrigation by 0.02% liquor nitrofurazoni then pulling out uric catheter after filling of bladder, the control group was pulled out uric catheter by routine method, the first micturition time after pulling out uric catheter of the two groups were observed and compared. Results Forty eight cases of the experimental group and thirty nine cases of the control group can micturate by themselves, there was significantly different between the two groups (P＜0.01). The first micturition time of the experimental group was (2.5±1.09) h while the control group was (3.31±1.35) h, there was significantly different between the two groups (P＜0.01) . Conclusions Bladder irrigation before pulling out uric catheter after craniotomy can promote the micturition early and favorably, avoid the elevation of blood pressure effectively, prevent the uroschesis, reduce the urethral infection and other complications, with important meaning to promote the rehabilitation of the patients.     

肠内营养对重型破伤风患者营养支持的探讨

Objective To study the effect of enteral nutrition on patients with severe tetanus. Methods The patients totaled 60 cases were divided into two groups with 30 cases in each. The patients in EN group were treated with enteral nutrition on basis of routine treatment, control group was treated with total parenteral nutrition (TPN). The indicators values of BMI, TSF, MAMC, TP, PAm, m, ALB and Hb were tested on the day before nutrition supports and after nutrition supports 10 days later in two groups. Adverse reaction and the treatment effect were observed simultaneously. Results With nutritional supports 10 days later, two groups had no obvious decline in BMI, TSF and MAMC. TP, PA, ALB and Hb of EN group were higher than those of control group (P＜0.05) . Complication rate of EN group was lower than that of control group, there was significant differences (P＜0.05) . Conclusions Early EN may improve protein metabo lism in patients with severe tetanus and nutritional status.     

肠内营养对重型破伤风患者营养支持的探讨

Objective To study the effect of enteral nutrition on patients with severe tetanus. Methods The patients totaled 60 cases were divided into two groups with 30 cases in each. The patients in EN group were treated with enteral nutrition on basis of routine treatment, control group was treated with total parenteral nutrition (TPN). The indicators values of BMI, TSF, MAMC, TP, PAm, m, ALB and Hb were tested on the day before nutrition supports and after nutrition supports 10 days later in two groups. Adverse reaction and the treatment effect were observed simultaneously. Results With nutritional supports 10 days later, two groups had no obvious decline in BMI, TSF and MAMC. TP, PA, ALB and Hb of EN group were higher than those of control group (P＜0.05) . Complication rate of EN group was lower than that of control group, there was significant differences (P＜0.05) . Conclusions Early EN may improve protein metabo lism in patients with severe tetanus and nutritional status.     

穴位注射治疗脑卒中假性球麻痹30例疗效观察

Objective To observe the curative effect of injectio ad acumen to 30 supranuclear paralysis cases with dysphagia. Methods cases were randomly divided into injectio ad acumen and single acupuncture treatment group, each of them has 30 cases respectively. Improvement of dysphagia was the main obserable index, and the data of pre-and post-treatment was being statistical treatment. Results the effective rate of injectio ad acumen and single acupuncture treatment group was 93.33% and 70.00% respetively, so there has significant stastical difference between the two groups(P ＜0. 01). Conclusion injectio ad acumen treatment has significant effect in patients with dysphagia.     

Clincal research of HA program combimed co-α-2b interferon on treatment of chronic myeloid leukemia

Objective To observe the HA program (3 harringtonine and Ara-C) co-α-2b interferon treatment of chronic myeloid leukemia in the feasibility and safety. Methods In our hospital from December 2005 to January 2009 out-patient and hospitalization in patients with CML were randomly assigned according to the principle of 51 cases were divided into 26 cases of the observation group and control group 25 cases. The control group were treated with α-2b interferon 3 × 106U subcutaneously or intramuscularly 3 times per week,intramuscularly 1 to 12 months to ease later changed to 2 times per week to maintain; treatment group therapy in the control group based on the GC small dose of HA programs: subcutaneous injection of Ara-C 20 mg,every 12 h one time; homoharringtonine alkaline 2 mg/d plus 5 % glucose solution 500 mL, by intravenous infusion over 4 h,in conjunction with the 7 ～ 14 d for a course of treatment monthly repeated a times, after 12 months depending on the circumstances every 2 to 3 months a time. Results The observation group and the control group,hematological remission total effective rates were 96.15% (25/26) and 72.0% (18/25),the observation group than the control group,2 group, the difference was significant (P<0.05); the observation group cytogenetic response overall response rates were 76.92% (20/26) and 20.0% (5 / 25), the observation group cytogenetic response overall response rate than the control group, 2 group, the difference was significant sex (P<0.05);two groups of patients with adverse reactions can be tolerated, does not affect the treatment. Conclusion Small dose of HA regimen combined with recombinant in terferon α-2b treatment of CML than single recombinant interferon α-2b high efficacy, with lower white blood cell effects of apparent high rate of hematologic response, no increase in adverse reactions and survival prolonged and so on.     

Clincal research of HA program combimed co-α-2b interferon on treatment of chronic myeloid leukemia

Objective To observe the HA program (3 harringtonine and Ara-C) co-α-2b interferon treatment of chronic myeloid leukemia in the feasibility and safety. Methods In our hospital from December 2005 to January 2009 out-patient and hospitalization in patients with CML were randomly assigned according to the principle of 51 cases were divided into 26 cases of the observation group and control group 25 cases. The control group were treated with α-2b interferon 3 × 106U subcutaneously or intramuscularly 3 times per week,intramuscularly 1 to 12 months to ease later changed to 2 times per week to maintain; treatment group therapy in the control group based on the GC small dose of HA programs: subcutaneous injection of Ara-C 20 mg,every 12 h one time; homoharringtonine alkaline 2 mg/d plus 5 % glucose solution 500 mL, by intravenous infusion over 4 h,in conjunction with the 7 ～ 14 d for a course of treatment monthly repeated a times, after 12 months depending on the circumstances every 2 to 3 months a time. Results The observation group and the control group,hematological remission total effective rates were 96.15% (25/26) and 72.0% (18/25),the observation group than the control group,2 group, the difference was significant (P<0.05); the observation group cytogenetic response overall response rates were 76.92% (20/26) and 20.0% (5 / 25), the observation group cytogenetic response overall response rate than the control group, 2 group, the difference was significant sex (P<0.05);two groups of patients with adverse reactions can be tolerated, does not affect the treatment. Conclusion Small dose of HA regimen combined with recombinant in terferon α-2b treatment of CML than single recombinant interferon α-2b high efficacy, with lower white blood cell effects of apparent high rate of hematologic response, no increase in adverse reactions and survival prolonged and so on.     

严多发伤并发症的早期控制

Objective To analyze the efficacy of early management of eomplications in patients with multi-ple traumas by applying the damage control theory. Method All total of 116 patients admitted to Wuhan Tongji Hospital between Jan 2006 and Jan 2008 were included in this retrospective study and were classified according to treatment method. Overall, 55 cases underwent damage control operations and 61 cases underwent conventional management. The groups of patients were compared in terms of parameters such as length of operation time, time to resuscitate from shock, lethal triad of death (LTD), complications and treatment outcomes after operation. Results The length of operation time was (67.43±19.52) min, resuscitation time from shock was (6.77±3.16) h and LTD was (11.54±4.10) h in the damage control group, and (163.95±55.41) min, (22.51±11.65) h and (34.55±5.63) h, respectively, in the conventional group, with significant differences between the two groups (P< 0.01). The per capita complication and mortality rates were 227.27 % and 3.64 %, respectively, in the dam-age control group and 363.93 % and 9.84%, respectively, in the conventional group (P <0.05). Couclusions Here, we demonstrated that early management of patients with multiple traumas undergoing operations by apply-ing the damage control theory significantly decreased the operation time, and decreased time to resuscitation from shock and LTD. Furthermore, this approach significantly reduced the incidence of comphcations and the mortality rate of patients with severe multiple traumas.     

血液灌流在急性重度有机磷农药中毒治疗中的应用

Objective The purpose of the study was to evaluate the applications and value of hemoperfusion (HP) in the treatment of acute severe organophosphorus pesticide poisoning. Method Patients who had been di-agnosed with acute severe organophosphorus pesticide poisoning were selected for the study between January and October 2008. The patients were randomly divided into three groups: A group (HA230-type hemoperfutor), B group (HA330-type hemoperfutor), and C group (control group, without HP treatment). Patients in the three groups underwent the same conventional treatments except for the HP. The curative effect, cholinesterase (CHE) activities and the levels of TNF-α, IL-1β,IL-6, and IL-8 in serum were statisticaUy analyzed. Results The cure rate of the A and B groups was significantly higher than the C group (P≤0.05). The cumulative dosage of at-ropine and average hospitalization days in the C group were significantly higher than the patients in the A and B groups (P <0.01). As well, the CHE activities were obviously up-regulated after the HP h-eatment in A and B groups (P < 0.01). At 24 hours after HP treatment, the level of CHE activities in the B group was much higher than the level in the A group (P≤0.05). Levels of TNF-α, IL-1β, IL-6, and IL-8 were down-regulated after the HP treatment in the A and B groups (P < 0.01). An internal comparison revealed that the levels of TNF-α, IL-1β, IL-6 and IL-8 were lower in the B group than the A group (P <0.01). Conclusions HP can be used for treating acute severe organophosphorus pesticide poisoning, likely functioning by absorbing poisons from the blood and acting to reduco inflammatory cytokines.     

严多发伤并发症的早期控制

Objective To analyze the efficacy of early management of eomplications in patients with multi-ple traumas by applying the damage control theory. Method All total of 116 patients admitted to Wuhan Tongji Hospital between Jan 2006 and Jan 2008 were included in this retrospective study and were classified according to treatment method. Overall, 55 cases underwent damage control operations and 61 cases underwent conventional management. The groups of patients were compared in terms of parameters such as length of operation time, time to resuscitate from shock, lethal triad of death (LTD), complications and treatment outcomes after operation. Results The length of operation time was (67.43±19.52) min, resuscitation time from shock was (6.77±3.16) h and LTD was (11.54±4.10) h in the damage control group, and (163.95±55.41) min, (22.51±11.65) h and (34.55±5.63) h, respectively, in the conventional group, with significant differences between the two groups (P< 0.01). The per capita complication and mortality rates were 227.27 % and 3.64 %, respectively, in the dam-age control group and 363.93 % and 9.84%, respectively, in the conventional group (P <0.05). Couclusions Here, we demonstrated that early management of patients with multiple traumas undergoing operations by apply-ing the damage control theory significantly decreased the operation time, and decreased time to resuscitation from shock and LTD. Furthermore, this approach significantly reduced the incidence of comphcations and the mortality rate of patients with severe multiple traumas.     

拔尿管前行膀胱冲洗对开颅术后患者的影响

Objective To discuss the influence of bladder irrigation before pulling out catheter on the patients after craniotomy. Methods One hundred conscious patients after craniotomy were randomized into the experimental group and control group, each with 50cases. The experimental group was given bladder irrigation by 0.02% liquor nitrofurazoni then pulling out uric catheter after filling of bladder, the control group was pulled out uric catheter by routine method, the first micturition time after pulling out uric catheter of the two groups were observed and compared. Results Forty eight cases of the experimental group and thirty nine cases of the control group can micturate by themselves, there was significantly different between the two groups (P＜0.01). The first micturition time of the experimental group was (2.5±1.09) h while the control group was (3.31±1.35) h, there was significantly different between the two groups (P＜0.01) . Conclusions Bladder irrigation before pulling out uric catheter after craniotomy can promote the micturition early and favorably, avoid the elevation of blood pressure effectively, prevent the uroschesis, reduce the urethral infection and other complications, with important meaning to promote the rehabilitation of the patients.     

严多发伤并发症的早期控制

Objective To analyze the efficacy of early management of eomplications in patients with multi-ple traumas by applying the damage control theory. Method All total of 116 patients admitted to Wuhan Tongji Hospital between Jan 2006 and Jan 2008 were included in this retrospective study and were classified according to treatment method. Overall, 55 cases underwent damage control operations and 61 cases underwent conventional management. The groups of patients were compared in terms of parameters such as length of operation time, time to resuscitate from shock, lethal triad of death (LTD), complications and treatment outcomes after operation. Results The length of operation time was (67.43±19.52) min, resuscitation time from shock was (6.77±3.16) h and LTD was (11.54±4.10) h in the damage control group, and (163.95±55.41) min, (22.51±11.65) h and (34.55±5.63) h, respectively, in the conventional group, with significant differences between the two groups (P< 0.01). The per capita complication and mortality rates were 227.27 % and 3.64 %, respectively, in the dam-age control group and 363.93 % and 9.84%, respectively, in the conventional group (P <0.05). Couclusions Here, we demonstrated that early management of patients with multiple traumas undergoing operations by apply-ing the damage control theory significantly decreased the operation time, and decreased time to resuscitation from shock and LTD. Furthermore, this approach significantly reduced the incidence of comphcations and the mortality rate of patients with severe multiple traumas.     

严多发伤并发症的早期控制

Objective To analyze the efficacy of early management of eomplications in patients with multi-ple traumas by applying the damage control theory. Method All total of 116 patients admitted to Wuhan Tongji Hospital between Jan 2006 and Jan 2008 were included in this retrospective study and were classified according to treatment method. Overall, 55 cases underwent damage control operations and 61 cases underwent conventional management. The groups of patients were compared in terms of parameters such as length of operation time, time to resuscitate from shock, lethal triad of death (LTD), complications and treatment outcomes after operation. Results The length of operation time was (67.43±19.52) min, resuscitation time from shock was (6.77±3.16) h and LTD was (11.54±4.10) h in the damage control group, and (163.95±55.41) min, (22.51±11.65) h and (34.55±5.63) h, respectively, in the conventional group, with significant differences between the two groups (P< 0.01). The per capita complication and mortality rates were 227.27 % and 3.64 %, respectively, in the dam-age control group and 363.93 % and 9.84%, respectively, in the conventional group (P <0.05). Couclusions Here, we demonstrated that early management of patients with multiple traumas undergoing operations by apply-ing the damage control theory significantly decreased the operation time, and decreased time to resuscitation from shock and LTD. Furthermore, this approach significantly reduced the incidence of comphcations and the mortality rate of patients with severe multiple traumas.     

Traction combined with manual therapy on 70 cases of cervical spondylopathy

Background:Traction of cervical vertebrae is an effective method in treatment of cervical spondlopathy.Manual therapy can correct dysfunction,has the effects of function exercises and has an active significance to the rehabilitation of mixed cervical spondylopathy.Combination of these two methods could enhance therapeutic effects and do good to functional recovery.Objective:To observe effects of traction combined with nanual therapy on mixed cervical spondylopathy.Subjects:70 cases of mixed cervical spondylopathy from January 2000 to January 2001 were investigated including 49 males and 21 females,aged 21-48(mean:34.8)years old with disease course 1 week t 6 months.All cases were treated by non-operative therapy.Among these patients,numbness of upper limbs,22 cases,pain at neck,shoulder,back,40 cases.Pressure measurement by compression of neck was positive in 10 cases,brachial plexus pulling test was positive in 5 cases and lowering head test was positive in 11 cases.X-ray and CT examination showed abnormal curvature,hypertrophy of front and back edges of vertebrae,narrow intervertebral fossa in 51 cases,protrusion of intervertebral disc in 35 cases,prolapse in 25 cases,calcification of posterior langitudinal ligament in 48 cases.All cases were randomly divided into treatment group(n=36) and control group(n=34).there was comparability between two groups at age,sex,disease condition.brae:Traction began with 6 kg and 1 kg was increased every day.Maximal weight to male was 17 kg and female was 15 kg.Intermittent traction was wadopted,relaxing for 5 seconds after 5 seconds of traction.(2)Manual therapy:relaxing neck,pulling neck,lifting neck.Corresponding acupoints were compressed with thumb along brachial nerve.If the acupoint were selected correctly and “De qi” was felt,the patient,might feel comfortable after manual therapy.In the end.rolling and rotating manipulation,beating were adopted at neck,back and relaxing manipulation was adopted to upper libs 2 weeks was 1 therapeutic course.Simple manual therapy was adopted in control group.Main evaluation indexes:Marked:Clinical symptons disappeared,nedk could move freely and function recovered;Effective:Clinical symptoms disappeared basically and neck could take basic movement freely;Ineffective:no obvious alternation after treatment.Result:Marked:33 cases(92%)in treatment and 29 cases (85%)in control group;Effective:3 cases(8%)in treatment group and 4 cases(12%)in control group,Inefective:0 case in treatment group and 1 case(3%)in control group.Therapeutic effect in treatment group were superior to that in control group.Conclusion:Traction of cervical vertoebrae combined with manual therapy had an obvious effect on mixed cervical spondylopathy in relieving spasm of neck muscle and restoring of articular tunction.     

脊髓损伤患者实施间歇导尿指征的研究

Objective To know the indication for patients with spinal cord injury during the course of intermittent urethral catheterization.Methods Divided 33 patients with spinal cord injury into the experimental group(18 cases)and control group(15 cases)randomly.The indication of beginning in the experiment group was less than 500 ml transfusion per day,without press ulcer,more than 150 ml bladder capacity.The indication in the control group was＞28 cm H2O pressure of bladder.Compared the effects between the two groups.Results The incidence rate of infection in the experiment group was lower than control group,all the indexes of uretharal catheterization were better in the experiment group than those of in the control group.Conclusions The indication of less than 500ml transfusion per day,without press ulcer,more than 150 ml bladder capacity are proper.     

抗栓药物联合治疗急性脑梗死

Objective To investigate the efficacy and safety of combinative antithrombotic therapy for patients with acute cerebral infarction who were not eligible for thrombolysis. Methods Eighty-three patients with acute cerebral infarction at six to twelve hours after the onset were randomly allocated into two groups : treat-ment group(n=46) recived batroxobin, aspirin and dipyridamole; control group(n=37) received aspirin. Neuro-logic impairment scole was measured at days 0, and 14. Barthel index of the two groups were observed at days 0 and 90. Blood coagulation action of the treatment group was also measured at days 0,5 and 11. Results In treatment group, the nervous function defect integral examined 14 d after trearment (12.7±6.4 )was markedly decreased than that of control group (20.1±7.2). A remarkable difference (P<0.01 ) was noticed between them. The Barthel index of the treatment group at 90 d after trearment (86.8±12.9 )was markedly increased than that of control group(43.4±15.1 ) (P<0.01 ). The total effective rate of treatment group and control group were 93.5% and 56.8% respectively( P<0.01). Conclusion The efficacy of combinative antithrombotic therapy for patients with acute cerebral infarction who were not eligible for thrombolysis is better than aspirin a-lone. Further more, the risk of bleeding may not increase in combinative antithrombotic therapy.     

护理干预对艾滋病患者亲属照顾者不良心理行为表现的影响

Objective To investigate mining intervention's influence on relative caregivers of AIDS patients with adverse psychological reactions and behavior. Methods Sixty five cases with advene psychological reactions and behavior of the relative caregivers of AIDS patients in hospital were selected and randomly divided into control group 30 cases and observation group 35 cases. Relative caregivers of patients in control group were given routine nursing care, while nursing interventions were added in observation group, the two groups of caregivera' adverse psychological reactions and behavior were observed. Results The patients relative caregiven in observation group with advene psychological reactions and behavior were significantly reduced compared with the control group. The difference was statistically significant (P＜0.01) . Conclusions Nursing intervention can reduce advene psychological reactions and behavior of relative caregivers of AIDS patients, and play a active role to them.