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1.
TheresearchgroupledbyProfessorWuYiminghasbeenengagedintheresearchofprofessionaltumorformanyyears ,especiallyengagedintheresearchofcharacteristicsoflungtumorcausedbypolyaromaticcompounds ,carcinogen esismechanismandtheresearchofearlydiagnosisofprofessio…  相似文献   

2.
Hepaticangiosarcomaisararemalignantvasculartumor Accuratepreoperativediagnosisofthistumorisverydifficultifthepatientdoesnothaveanyhistoryofexposuretospecificcarcinogensincludingthorotrast,arsenicalsandvinylchloridemonomer WedescribeCTfindingsintwocase…  相似文献   

3.
Tumorigenesisproceedsthroughanaccumulationofspecificgeneticalterations Recentstudieshavefocusednotonlyonthederegulationofcellproductionbutalsoontheinhabitationofcellloss Thisstudyassessedtherelationshipbetweenapoptoticstatusandbiologicalbehaviorduring…  相似文献   

4.
Thedetectionrateofresectablesmallpancreaticcarcinomaisincreasingasaresultofrecentadvancesinvariousdiagnosticimagingtechniques However,resectionatthetimeofdiagnosisispossibleinonly 5 % - 2 2 %ofpatients ,1andmostpatientshadadvancedpancreaticcarcinomawhenfound …  相似文献   

5.
Role of p38 protein kinase in heat-induced Raw cells apoptosis   总被引:5,自引:1,他引:4  
Aftercellsareexposedtoastressingagent,celldeathcanbeobservedasapoptosis,necrosisandmitoticdeathApoptosisorphysiologiccelldeath,isundergeneticcontrolandischaracterizedmorphologicallybycellshrinkage,marginationofchromatinandnuclearfragmentationGenomicDNA…  相似文献   

6.
Gastriccancerisamajorhealthcareproblemandthesecondmostcommonfatalcancerworldwide Inthelastdecade,betterinsighthasbeengainedintothemolecularbasisunderlyingtheneoplasitctransformationofstomach Thedramaticvariationintheincidenceofgastriccancerindifferent…  相似文献   

7.
Molecular genetic analysis of a Chinese patient with Fabry disease   总被引:4,自引:0,他引:4  
FabrydiseaseisanX linkedlysosomalstoragediseasecharacterizedbyaccumulationofglycosphingolipidsinendothelialcells,fibroblasts,smoothmusclecells,andepithelialcellsofthekidney Thereisacharacteristicskinlesion,angiokeratomacorporisdiffusumuniversalis,whichc…  相似文献   

8.
Itisdifficulttoblockthetransmissionofschistosomiasisbychemotherapy ,thereforemanyresearchershavebeeninterestedinthestudyofvaccineofschistosomiasis Thestudyofvaccineofschistosomiasiswasmostlyfocusedonanti infectionimmunity ,butthemosthopefulcandidatemole…  相似文献   

9.
Ithasbeenreportedthattheclassicalmodelofthedominanceofthelefthemisphereofhumanbrainisincorrectbecauseitisinaccuratetosaythatwhichhemisphereisdominant Thehemispheresareasymmetricalintheirfunction Inthisstudywetriedtofindouttheactivatedareasandtoconfirm…  相似文献   

10.
Chroniccutaneousulcersrepresentamajorhealth careproblemwithconsiderablesocioeconomicimpact 1,2Traditionally,localtreatmentofchroniccutaneousulcersconsistsofconstantlocalwoundcare ,surgery ,skingrafting,debridementandvascularreconstruction Chroniculcersmayi…  相似文献   

11.
Themechanismofbloodflowduringclosed chestcardiopulmonaryresuscitation (CPR )inhumanbeingsremainscontroversialdespitethefactthatmodernCPRhasgainedwidespreaduseinclinicalpracticeformorethanfourdecades Twoprincipalandcompetinghypotheseshavebeenproposedtoex…  相似文献   

12.
Inunexpectedtestimony2totheversatility3ofthebody′scells,researchershavefoundtheycanmakebonemarrowcellsturnintomuscle,causingmicewithmusculardystrophy4toproducecorrectlyworkingmusclecellsTheexperimentsuggeststhataformofbonemarrowtransplant--awellestablis…  相似文献   

13.
The role of c-myc in regulating mdr1 gene expression in tumor cell line KB   总被引:5,自引:0,他引:5  
Thec mycproto oncogeneplaysaroleinmanycellularprocesses ,suchasproliferation ,differentiationandapoptosis Itisanearly responsegenenecessaryforcell cycleprogression (G1 Stransition)andactivatesquiescentcellsintothecellcycle (G0 G1transition) Down regulationofc …  相似文献   

14.
CelladhesionmoleculesmaymediatethechemotacticmigrationbetweencellsorcellsandinterstitiumRecentstudies1,2havefoundthatdialysiswithcellulosemembranescouldleadtochangesintheexpressionofleukocyteadhesionmolecules,suchasCD11bandLselectin,ongranulocytesandmon…  相似文献   

15.
Woundhealingistheprocessbywhichcellproliferationisstringentlycontrolled ProgressionthroughtheG1phaseandinitiationofthecellcycleinmammaliancellsdependsonthebalanceofinteractionbetweencellcyclepositiveregulatorssuchascyclinD1,cyclinE ,cyclin dependentkina…  相似文献   

16.
Leishmaniaparasiteinfectionnotonlycausescateoneousandmucosallesions,butalsoviseralLeishmaniasis1 ThestudyindicatedthatLeishmaniainfectioncouldevokeinfectedsubject’simmunesystemandacquiredprotectiveimmunityandinhibitsecondaryLeishmaniainfections2 So…  相似文献   

17.
Lymphangiomyomatosis   总被引:1,自引:0,他引:1  
Lymphangiomyomatosis (LAM )isaprogressivediseaseaffectingwomenofchildbearingage Itismicroscopicallycharacterizedbyabnormalsmoothmuscleproliferationthatcausesgradualobstructionofsmallairways ,lymphaticsandvasculature Theproliferationeventuallyresultsinach…  相似文献   

18.
Hyperplastic callus in osteogenesis imperfecta.   总被引:1,自引:0,他引:1  
HyperplasticormassivecallusinosteogenesisimperfectaisanunusualbutimportantmanifestationbecauseofitsspecialclinicalandradiologicalfeaturesOnlysometensofcaseswerereportedinliterature,15 andnonehasbeendocumentedinChinaasyetTheauthorscollectedsixcases…  相似文献   

19.
Mostofgynecologicmalignancesaresensitivetochemotherapy Bonemarrowsuppressionisthemaindose relatedtoxicityofmanychemotherapeuticdrugs Standardtreatmentforthiscomplicationinvolvestheuseoftransfusionalsupport,hematopoieticcytokines ,pharmacologicalrescue ,a…  相似文献   

20.
Pectusexcavatumisthemostfrequentanteriorchestwalldeformityandisproducedbyposteriordepressionofthesternumandlowercostalcartilage Itoccursmorecommonlyinboysbyalmosta 4∶ 1ratio Thesternumandcostalcartilagethatareangledposteriorlymaydecreasethechestvolume,r…  相似文献   

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