食品级大豆油W/O徽乳的制备研究

制备了水/Span80-Tween80/醇/大豆油食品级微乳。选用助乳化剂浓度法制备微乳液。用改良三角相图法筛选得到了能形成大豆油微乳的食品乳化剂。考察了助乳化剂及其浓度对增溶水量的影响。电导率法区分了微乳液的油包水(W/O)、双连续(B.C.)和水包油(O/W)类型。结果表明,大多单一食品乳化剂不能形成W/O大豆油微乳,Span80和Tween80复配后HLB值在9.7～12.9之间时能获得相对大面积的可转相微乳区域。乳化剂与油的相对比例不同,助乳化剂助溶效果不同。甘油是低乳化剂含量下效果相对较佳的助乳化剂,其浓度为25%时的增溶效果相对较好。     

PGFE/BOPP防雾薄膜的制备与性能研究

用表面活性剂聚甘油脂肪酸酯(PGFE)对BOPP薄膜进行表面改性,降低薄膜表面张力,使其具有防雾作用。以聚甘油脂肪酸酯为防雾剂,采用涂布法制备得到PGFE/BOPP防雾薄膜,通过试验测定分析了薄膜的防雾性能,机械性能、光学、透氧、透湿等性能。结果表明:涂布PGFE后,薄膜拉伸强度增大、雾度增大,透光率降低,对氧气、水蒸气的阻隔性提高,其中2%浓度的PGFE涂布后,BOPP薄膜防雾效果,机械性能较好,可以作为防雾包装薄膜使用。     

Effects of age on human cumulative irritation responses

The rheological properties of the microemulsion region of the SDS, pentanol, and water micellar system have been studied experimentally. The W/O and O/W microemulsions behave as typical Newtonian fluids: viscosity remains constant independent of the shear rate. For the bicontinuous system the shear-thinning effect is observed. The addition of ascorbic acid to the system caused a microemulsion viscosity increase, which was the highest in the bicontinuous region and at the lowest temperature.     

食品级微乳液的研究进展

微乳液(microemulsion,简称ME)是由两种互不相溶的溶剂形成的热力学稳定体系,在医药、化妆品以及采油等领域都有广泛的应用,但在食品领域的研究还比较少。研究表明微乳液能够提高亲水性或亲脂性物质的溶解度,并能作为化学或酶法反应的有效介质,引起了广大食品领域科学工作者的关注。本文对食品级微乳液的制备、增溶作用以及作为微反应器等进行了综述。     

薰衣草精油微乳体系的相行为、微观结构转变和清除自由基活性

薰衣草精油具有镇静安神、抗氧化等特性,但其疏水性限制了其在食品行业中的应用。本研究通过微乳化技术构建薰衣草精油微乳液运载体系,研究其相行为及微观结构转变对其清除自由基活性的影响。通过三元相图发现,二丙二醇作为助表面活性剂可以把微乳单相区面积扩大至71.4%;通过染色法、电导率的测定,确定微乳体系微观结构转变,水分质量分数分别为0%～30%、40%～50%、60%～90%时,体系相应处于W/O、双连续和O/W的结构类型,且在双连续阶段体系黏度达到峰值。同时,微乳液对1,1-二苯基-2-三硝基苯肼自由基清除率随着水分体积分数增加而提高;2,2’-联氮-双-3-乙基苯并噻唑啉-6-磺酸阳离子自由基清除率在W/O和双连续型阶段先下降,转变为O/W型时回升,并在水分体积分数70%时达到最大值。该多元微乳体系有效实现了薰衣草精油的增溶,且其物理特征和抗氧化性的变化与微观结构密切相关。     

Tween80/异丙醇/丁酸乙酯/生理盐水体系微乳相结构及其作为姜黄素载体的研究

目的研究Tween80/异丙醇/丁酸乙酯/生理盐水体系的拟三元相图及其微乳相结构转变,并研究该体系的药物释放行为。方法用电导率法和循环伏安法测定微乳相结构转变。用紫外-可见分光光度计法测定姜黄素的溶解度,并探索水包油（O/W）型微乳载体中姜黄素的包封率和释放行为。结果研究表明,微乳结构在较低盐水浓度下形成油包水（W/O）型微乳,在中等盐水浓度转变为双连续型结构,在高盐水浓度连续转变为O/W型结构。O/W型微乳作为载体对姜黄素具有包封、增溶和缓释的作用。结论本实验中O/W型微乳对姜黄素具有一定的包封和缓释,鉴于体系的低毒性,期望对制药工业起到指导作用。     

Microemulsion-based anthocyanin systems: effect of surfactants,cosurfactants, and its stability

Anthocyanins exhibit natural antioxidants but exhibit poor stability and low oil solubility. Therefore, increasing the stability and fat solubility of anthocyanins is necessary to broaden their applications. In our experiment, an anthocyanin microemulsion system was constructed and its stability was investigated. At an oil phase and emulsifier ratio of 7:3, the hydrophilic oil-wet value reached 7.5 and the Km was 2:1. Furthermore, the microemulsion area was the largest. The bicontinuous region of the microemulsion exhibited optimal experimental conditions and resulted in a microemulsion containing 425.54 ± 1.58 μg/g anthocyanins. The anthocyanin microemulsion was a water-in-oil type, with a particle size of 0.07 ± 0.009 μm. Moreover, the temperature, light, and sample observation tests showed that the anthocyanin retention rate in the microemulsion was higher than that in the anthocyanin solution. Low-concentration NaCl and less than 9% of glucose and sucrose exerted no significant influence on the anthocyanin microemulsion stability.     

DMC/AM/AA反相微乳液体系的制备与优化

以甲基丙烯酰氧乙基三甲基氯化铵(DMC)、丙烯酰胺(AM)和丙烯酸(AA)为乳化单体,采用电导率法和目测法相结合的方式,考察了复合乳化剂的亲水亲油平衡值(HLB)、水相单体浓度和配比、油水质量比等因素对体系电导率和水相增溶量的影响,制备了稳定的DMC/AM/AA反相微乳液体系,优化了反相微乳液体系的制备条件。结果表明,最佳油相为环己烷,最佳乳化体系为Span80-Tween60;HLB为10.48,水溶液中单体总浓度为50%,n(DMC)∶n(AM)∶n(AA)为1.5∶7∶1.5,油水质量比为2∶1时,体系的电导率变化较为平稳,增溶水量也较多,可以得到澄清稳定的反相微乳液体系。     

RYOTO蔗糖酯在乳制品中的应用

<正> RYOTO蔗糖酯是三菱化学食品株式会社的产品,也是食用乳化剂的顶级品牌品。它是由蔗糖和天然植物脂肪酸通过酯化合成的具有安全性的非离子表面活性剂。     

W/O型中链脂肪酸微乳的制备及其性质的测定

以中链脂肪酸(MCFA)为原料,用HLB值法制备的W/O型中链脂肪酸(MCFA)微乳,可提高油溶性药物或营养物的溶解性和生物利用率.考察了滴定方法,确定用蒸馏水滴定MCFA、表面活性剂和助表面活性剂三组分的混合物为最佳;通过乳化效率、伪三元相图和反应过程中的现象,得到制备W/O型MCFA微乳的最适HLB值为4.7,最佳表面活性剂为单独使用司盘60,最佳助表面活性剂为异丙醇,最优配方为m司盘60:m异丙醇:mMCFA:m蒸馏水=1:2:3:0.5.考察优化配方的理化性质,初步稳定性良好,表面张力可达到25.50 mN/cm,粘度50.06 cP,电导率3.31 μs/cm,粒径20.1±3.3 nm,zeta电位-6.23 mV.     

虫白蜡高级烷醇微乳液的制备及其在功能饮料中的应用

为解决虫白蜡高级烷醇不溶于水,难应用于澄清稳定型功能饮料的瓶颈问题,制备高负载量的高级烷醇微乳液,获得其最佳乳化条件,通过伪三元相图确定微乳区域,评价其稳定性,并将其作为功能性添加剂配制高级烷醇功能饮料。结果表明：当复配乳化剂亲水亲油平衡值为10,乳化温度为70～75 ℃时,得到各添加剂用量均在食品国家标准允许添加范围内的稳定澄清的高级烷醇微乳液;微乳的离心、冷热循环和稀释稳定性良好,室温贮藏65 d后依然稳定透明;伪三元相图中微乳区域随着Km值的减小而不断缩小;微乳与其他辅料复配后可以制备成透明稳定的高级烷醇功能饮料。将虫白蜡高级烷醇制备成微乳,有效解决了其不溶于水以及在饮料中稳定性差、极易上浮等问题,为制备高品质、透明稳定的高级烷醇功能饮料提供了一条有效途径,也为高级烷醇新产品的开发研究提供参考。     

Protective and restorative effects of a Commiphora mukul gum resin and triheptanoin preparation on the CCL-110 skin fibroblast cell line

Coenzyme Q10 (CoQ10) is a major ingredient in skin care products because of its anti‐wrinkle effects, although it has some side effects especially at higher amounts. In this study, we compare the anti‐wrinkle related properties of CoQ10 and a proprietary Commiphora mukul gum resin (guggul) and triheptanoin preparation (GU‐TC7). GU‐TC7 is prepared with a supercritical CO₂‐co‐solvent extraction with ethanol, standardized to 2% guggulsterones and triheptanoin, a triglyceride composed of three 7‐carbon fatty acids. Treatment of CCL‐110 skin fibroblasts with GU‐TC7 demonstrates a mild proliferative effect compared to CoQ10 and increased type I collagen synthesis. Additionally, GU‐TC7 inhibited matrix metalloproteinase‐1 (MMP‐1) expression in a dose‐dependent manner at 20–100 μg mL^?1 and inhibited human elastase expression by more than 50% as compared to no elastase inhibition with CoQ10 treatment. These results suggest that GU‐TC7 possesses properties that are applicable to the treatment of wrinkles and may be considered for its further evaluation in skin care products.     

溶血磷脂制备含沙棘油微乳液的研究

溶血磷脂比磷脂的HLB大,易形成O/W型乳化剂,可制备热力学稳定的微乳化体系.利用溶血磷脂作乳化剂,制备含沙棘油的微乳液,以沙棘油为油相,溶血磷脂为乳化剂,正丙醇为共表面活性剂,制成微乳液.最终产品呈透明、稳定的均相混合物.     

Effects of water-soluble soybean polysaccharide on rheological properties,stability and lipid digestibility of oil-in-water emulsion during in vitro gastrointestinal digestion

Water-soluble soybean polysaccharide (SSPS) is a naturally occurring emulsifier. SSPS was used as the sole emulsifier to stabilize an oil-in-water (O/W) emulsion. The effects were investigated of different SSPS concentrations (3–20% (w/w)) on the lipid digestibility, rheological properties and stability of O/W emulsions during in vitro digestion model. The droplet size of the emulsions tended to increase during the oral phase because the emulsions were unstable and droplets coalesced, except with a SSPS concentration of 20% (w/w). The presence of SSPS markedly reduced the free fatty acid (FFA) content after its stabilized O/W emulsion passed through in vitro gastrointestinal digestion. The amount of FFA significantly decreased as the concentration of SSPS increased due to SSPS stabilization film on oil droplet surface and high viscous system. SSPS may be an attractive alternative ingredient to control the lipid digestibility of emulsions for various food products.     

新资源食品牡丹籽油

牡丹籽油是从牡丹种子中提取出来的植物油。成分分析表明:牡丹籽油不饱和脂肪酸组成达92%,其中α-亚麻酸含量达42%,明显高于其他食用植物油,是一种营养价值很高的食用植物油。通过超临界CO2提取和精炼处理,食用安全无毒,符合《食用植物油卫生标准》。牡丹与其他油料作物比较,在规范化种植和工业化生产有明显优势。其在食用植物油工业、保健食品、化妆品工业和医药工业方面具有较好的开发利用前景。     

No. 5Vol 42, No. 4, pp. 313–318, 2008A New Water-in-Powder Technology A Novel Structure for Creating Unique Cosmetic Products

A Water-in-Powder cosmetic is one encapsulating a large amount of water with powders. In this study we explain why the cosmetic is possible. First we focused on hydrophilic and hydrophobic balance of nano-sized powder surface. We looked into the surface state of powders with the gas adsorption test and discovered the functional powders that have the optimized balance of hydrorepellency due to fractal surface and hydrophilicity due to free hydroxyl groups. By using this material, we created a new powder technology that can encapsulate a large quantity of water stably. We also looked into how the powders encapsulated water by observation with wet-SEM and how the encapsulated water is stabilized by measuring water mobility with ¹7Q-M\IJR As a result, we developed a new technology with water and powder. By encapsulating a large amount of water, we achieved a cosmetic with many unique characteristics : the powder cosmetic can change into liquid by application of friction on skin, it gives us comfort in use and provides a watery, cool feel. It also provides excellent makeup function by spreading smoothly on skin to form a uniform makeup coating.
Keywords:  water-in-powder, hydrorepellency, hydrophilicity, fractal, encapsulate, technology     

No. 3Vol. 42, No. 2, pp. 94–101, 2008Effect of Birch (Betula platyphylla Sukatchev var. japonica Hara) sap on cultured human epidermal keratinocyte differentiation

The beauty of ideal skin texture is closely associated with dermal moisture factors. The key factors of skin moisture are NMF (natural moisturizing factor) and skin normal barrier function. The former keeps dermal surface moisture, and the later protects from excess water loss. So we have searched for the ingredient that improves these factors. Birch sap has been widely used as an effective drink for anti-fatigue and anti-stress. However, the effect of birch sap on skin as a cosmetic agent has not been known entirely. In this study, we investigated the effects of birch ( Betula platyphylla Sukatchev var. japonica Hara) sap on human skin. Birch sap induced epidermal keratinocyte differentiation properties in vitro . We assessed two epidermal differentiation agents. Filaggrin is a precursor protein of NMF, and involucrin is one of the precursor proteins of the cornified cell envelope (CE), which is related to normal barrier function. We have evaluated the production of these proteins where birch sap was applied to human normal keratinocytes. Birch sap not only increased mRNA expression of filaggrin and involucrin, but also accelerated these proteins production. Otherwise, birch sap did not have any influence for IL-6 production, which is related to inflammatory and aberrant keratinocyte proliferation. The results of induced differentiation properties on birch sap-treated keratinocytes are very similar to the differentiation induced by calcium in vitro . This similarity suggested that birch sap has a differentiation inducible property on in vitro cultured keratinocytes. Our study suggested that birch sap is able to control both moisturizing- and barrier-related factor production. From these effects, birch sap provides appropriate epidermal functions and skin homeostasis, and revealed itself as a very useful ingredient in the cosmetic field.     

吐温80/正构醇微乳体系形成过程的介观模拟

利用耗散粒子动力学(DPD)方法对吐温80/正构醇(C2~C8)/丁酸乙酯/水四组分微乳体系形成过程进行了模拟,研究了醇类浓度及烃链长度对微乳形成过程相行为及微观结构的影响。研究发现:正构醇浓度和烷烃链长度对体系自组装形态变化有显著影响,当醇类浓度较低时,微乳粒径随醇浓度的增大而增大,当浓度增加到一定程度后,继续增加醇浓度则导致微乳形态从球状依次变为管道状、网格状;通过比较不同烷烃链长的微乳体系发生形态变化时醇的浓度大小,发现醇烷烃链长的增加促使微乳体系在醇浓度较低时就发生形态转变,且体系界面张力较快趋于稳定。同时,研究发现醇链长的增加会使吐温80/正构醇/丁酸乙酯/水体系的W/O型和双连续型微乳区增大。该结果为微乳类型及形态尺寸的调控从而实现蛋白质的选择性萃取提供指导。     

The effect of an amphiphilic self‐assembled lipid lamellar phase on the relief of dry skin

Humectant and occlusive technologies have traditionally been used for the treatment of dry skin. Originally, non‐lamellar‐forming ingredients were used such as petrolatum but recent research has shown the advantage of using lamellar‐forming ingredients such as ceramides, pseudoceramides and phospholipids in the relief of dry skin. Nevertheless, the importance of using lipid‐phase transition inducers, such as long‐chain fatty acids, has not been studied clinically. The evaluation of a novel complex of lipophilic ingredients was of interest: cetyl alcohol, isostearyl isostearate, potassium cetyl phosphate, cetyl behenate and behenic acid. The combination of all these ingredients was shown to be more effective than any single component in water vapour transmission rate studies. This was thought to be owing to the formation of a unique structural organization of the lipids upon dry‐down from an O/W emulsion as was examined by X‐ray diffraction and optical microscopy. When evaluated clinically in a randomized double‐blind and vehicle‐controlled moisturization efficacy trial, this novel blend of ingredients was shown to not only improve the visible signs of skin dryness to a significantly greater extent than a comparable mineral oil‐containing vehicle but also then maintain a better skin condition during the regression no‐treatment phase of the study. This combination of ingredients offers a new technology option for the treatment of dry skin.     

Coenzyme Q10 supplementation: Efficacy,safety, and formulation challenges

World population growth and aging are posing unprecedented challenges in sustaining the health of 9.1 billion people that will be occupying the planet by 2050. Although noncommunicable diseases such as cardiovascular and neurodegenerative diseases, cancer, and diabetes are among the top 10 global causes of death, they can be prevented by risk factor reduction, early detection, and adequate treatment. Since a healthy diet along with dietary supplementation could play an important role to reduce morbidity and cut off its associated health care costs, research in the food and nutrition area is required to find solutions to global challenges affecting health. As a result of the healthy living trend, dietary supplements category is growing fast, leading to an urgent need for dietitians, physicians, and policy makers to broaden the scientific evidence on the efficacy and safety of a wide range of active ingredients. Coenzyme Q10 (CoQ10), as the third most consumed dietary supplement, and as a potential candidate for the treatment of various noncommunicable diseases that are among the global top 10 causes of death, has gained interest over years. Scientific evidence regarding mainly CoQ10 efficacy and safety, as well as formulation challenges, is addressed in this review.