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1.
Factors influencing the expression of Fas and Fas ligand on newborn murine ker atinocytes and fibroblasts 总被引:2,自引:0,他引:2
Fas (CD95)andFasligand (FasL) ,asmembersofTNFfamilies ,aretypeⅠandtypeⅡcellulartransmembraneproteins FasLinducesapoptosisbybindingtoitsreceptorFasonthecellsurface Thisprocessisinvolvedinimmuneresponsetovirus ,tumorcellsandtheregulationoflymphocytehomeostasis… 相似文献
2.
Objective ToinvestigatetheexpressionofFas/APO1inthecourseofcellcycles-Methods Fas/APO1expressionofrenalcellcarcinoma(RCC)celllineGRC1cellssynchronizedbytwiceoverdosethymidineblocksandnitrousoxide(N2O)gaswasdetectedbymeansofflowcytometryemployingFI… 相似文献
3.
ZHU Changhong Mark D. Nixon WANG Yifang Andrew R. LaBarbera Center of Reproductive Medicine Tongji Hospital Tongji Medical University Wuhan Department of Obstetrics Gynecology University of Cincinnati College of Medicine Cincinnati Ohio Department of Molecular Cellular Physiology University of Cincinnati College of Medicine Cincinnati Ohio 《华中科技大学学报(医学英德文版)》1999,19(3):175-180
Syntheticoligodeoxynucleotides(ODNs)representanewtoolforthediscoveryofphysiologicalmechanismsincellcultures,intissuesandinvivo.Ideally,anantisenseODNistargetedinasequence-specificman-nertonucleicacids(RNAorDNA)tooffertheexcitingpossibilityofselective… 相似文献
4.
QingJing 《第二军医大学学报》1999,20(10)
Oxidized low -density lipoproteins (oxLDL) have been show n to play a crucialrole in atherosclerosis, butthe underlyingm olecularm echanism s have notbeen fully understood. The presentstudy show ed thatoxLDLstrongly evoked phosphoryla-tion and activation ofp38 m itogen-activated protein kinase (MAPK) in ratvascular sm ooth m uscle cells (VSMCs) in concen-tration-and tim e-dependentm anners, reaching the m axim alactivation at100 μg/m lwithin 5 m inutes. The results from im -m unofluorescence staining also revealed thatp38 MAPK w as activated by 相似文献
5.
Objective Toinvestigatetheeffectsofarotinoidacid(Ro13 7410 )onthemorphologicalandfunctionalalterationsofleukemiaHL 60celllineandcomparedwiththoseofRA Methods DifferentiationofHL 60cellswasassessedbymorphologyandbyNBTreduction Trypanblueexclusionwasusedtodeter… 相似文献
6.
CytotoxicityofHumanLAKCellsAgainstMitoticPhaseTumorCellsLiuGuorong(刘国荣),LiDianjun(李殿俊);BaDenian(巴德年)andMengXiaobo(孟晓波)(Cancer... 相似文献
7.
《中国现代医学杂志》2001,(12)
Thesis·AcuteEffectsofChineseHerbsonthePeritonealDialysisEfficacyandPeritonealUltrastuctureXiChunsheng ,etal.1:( 1)…………………EffectsofHaslPlusChemotherapyonPeripheralBloodTCellSubsetsandNKCellActivityinPatientswithOvarianEpithelialCarcinomaZhuGenhai,etal.1:( 3)…… 相似文献
8.
螺旋藻多糖对CD3AK细胞增殖能力的影响 总被引:3,自引:0,他引:3
研究了螺旋藻多糖(PS)对CD3McAb激活的杀伤细胞(CD3McAb activated killer cells,CD3AK cells)增殖能力的影响。结果表明,当PS浓度为2.5μg/ml培养体系条件下,对CD3AK细胞具有明显的刺激细胞增殖作用(P〈0.02);对培养长达23d的CD3AK细胞杀伤肿瘤细胞(KL562细胞)的活性仍维持在较高的水平(46.5% ̄50%)。 相似文献
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EXPRESSION OF INTERCELLULAR ADHESION MOLECULE IN LUNG TISSUES OF EXPERIMENTAL ACUTE LUNG INJURY AND THE AFFECT OF RHUBARB ON IT 总被引:1,自引:0,他引:1
INTRODUCTION ICAM 1alsonamedCD54,isanadhesionmoleculeonthecellularsurfaceandamemberofimmunoglobulinsuper family(1) .Inrecentyears ,alongwiththedevelopmentofimmunologyandmolecularbiologictechnique ,thestudyonICAM 1hasbeenprogressedforagreatdeal.Itisdiscov ere… 相似文献
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TheInfluenceofThymectomyonGerm-cellsoftheTestisinMiceZENGJin(曾进),ZHANGYong-shang(章咏裳);S.POMER,G.STAEHLERREN;Da-hong(任大洪)(Depa... 相似文献
11.
INTRODUCTION Themethodofcoldliverpreservationisacruciallimit ingfactorinthedurationofliverpreservation .Experimentalevidencehasshownthatnonparenchymalcellsaremorevulnerabletohypothermicstoragethanhepatocyte,indicatingthatprotectionofthemicrovasculatur… 相似文献
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Influence of Buyang Huanwu Decoction (补阳还五汤) on Activity of Blood Platelet Activating Factor Receptor in Rabbit 下载免费PDF全文
BuyangHuanwuDecoction(BYHWD)isaChinesetraditonalmedicamentwhichhasbeenusedinclinicalpracticeforalongtime.ItiscomposedofrawRadixAstragalus120g,RadixAngelicaSinensis6g,RadixPaeoniaRubra4.5g,RhizomaLigusticumWallichii,SemenPersica,FlosCarthamusandLumbricus… 相似文献
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TheclinicaleffectandvalueofCD3AK(CD3monoclonalantibodyactivatedkillercells)wereinvestigatedin45caseswithmiddle-advancedcancer... 相似文献
14.
Dendriticcells (DCs)arethemostpowerfulantigen presentingcells (APCs) DCshavetheuniquecapacitytostimulatenaiveTcellstoinduceanantigen specificprimaryimmuneresponse ,whereasotherAPCscanonlyactivatealreadystimulatedTcells 1 Atthistime ,themechanismunderlyingth… 相似文献
15.
Objective Tostudytheeffectsofarachidonicacid,linoleicacid,andkupffercellconditionedmedium(KCCM)derivedfromarachidonicacidandlinoleicacidtreatmentonproliferationofrathepaticstellatecells(HSC)-Methods HSCandkupffercellswereisolatedandculturedfromliver… 相似文献
16.
INTRODUCTION Graves’disease(GD)isoneoftheautoimmunethyroiddiseases(AITD) ,andischaracterizedbyhypermetabolicandhyperthyroidsyndromecausedbyTSHreceptor stimulatingantibody TheetiologyandpathogenesisofGDarestillnotfullyclarified TheroleofTcellswaswidelyst… 相似文献
17.
OxLDL-inducedCytotoxicityandItsInhibitionbyAPI_(0134)inCulturedPorcineAorticEndothelialCellsWANGHongwei(王宏伟);ZHAOHuayue(赵华月);?.. 相似文献
18.
Objective ThetumorsuppressorgeneCDKN2A,locatedonchromosome9p21,encodesthecellcycleregulatoryproteinp16.InactivationofCDKN2Agenecouldleadtouncontrolledcellgrowth.InordertodeterminetheroleofCDKN2Ainthedevelopmentofsporadicovariancancerweexaminedlossofh… 相似文献
19.
DetectionofHumanPapillomavirusGenesinParaffin-embeddedHumanOralSquamousCellCarcinomasbyPolymeraseChainReactionandRFLPAnalysis... 相似文献
20.
Oxidized low density lipoprotein inhibited tissue factor pathway inhibitor mRNA expression in human endothelial cells 总被引:1,自引:0,他引:1
ethods LowdensitylipoproteinwasisolatedfromnormalheparinizedbloodbydensitygradientultracentrifugationandoxidizedbyCuCl2 TotalRNAwasextractedfromhumanumbilicalveinendothelialcells (HUVECs)exposedtoLDLorOX LDL ,usingtheguanidiniumisothiocyanatemethod Thequ… 相似文献