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1.
ObjectiveTodeterminethequalityoflife(QOL)ofmildhypertensivepatientstreatedwithcaptoprilascomparedtoplacebo.MethodsThisisarand...  相似文献   

2.
Hepatocellularcarcinoma (HCC)ranksthirdamongthecausesofcancermortalityinChina ,andabout4 2 5%oftheworld’snewcasesofHCCeachyearoccurinChina 1EpidemiologicstudiesprovideevidencethatinfectionwithhepatitisB (HBV )and/orhepatitisC (HCV ) ,andingestionofaflatoxinBcon…  相似文献   

3.
Repair of stricture of cervical esophagus with platysma myocutaneous flaps   总被引:5,自引:0,他引:5  
Itisverydificulttoachieveasuccesforscarstenosisofthecervicalesophagusandanastomoticstenosisaftercolonorstomachtranspositionto...  相似文献   

4.
Noninsulindependentdiabetesmelitus(NIDDM)isnowconsideredtobeacomplexdiseaseresultingfromgeneticandenvironmentalfactors.Mutat...  相似文献   

5.
TheC→TsubstitutionatthepositionofIVS2nt.654(IVS2654C→T,β654),amutationcausingdefectinRNAsplicing,isoneofthemostcommonβtha...  相似文献   

6.
Althoughmanyhypothesesofanesthesiahavebeenproposed,includingenhancementofinhibitionandalsodepressionofexcitatorysynaptictransmission,theexactmechanismofactionofgeneralanestheticsonthecentralnervoussystemremainsundefined1 However,specifiedtargetsitesofa…  相似文献   

7.
Leishmaniaparasiteinfectionnotonlycausescateoneousandmucosallesions,butalsoviseralLeishmaniasis1 ThestudyindicatedthatLeishmaniainfectioncouldevokeinfectedsubject’simmunesystemandacquiredprotectiveimmunityandinhibitsecondaryLeishmaniainfections2 So…  相似文献   

8.
The role of c-myc in regulating mdr1 gene expression in tumor cell line KB   总被引:5,自引:0,他引:5  
Thec mycproto oncogeneplaysaroleinmanycellularprocesses ,suchasproliferation ,differentiationandapoptosis Itisanearly responsegenenecessaryforcell cycleprogression (G1 Stransition)andactivatesquiescentcellsintothecellcycle (G0 G1transition) Down regulationofc …  相似文献   

9.
Membraneabnormalitiesinhumanessentialhypertensionsarewellestablished1 Toxicoxygenmetabolitessuchassuperoxideanionshavebeenimplicatedintissueinjurytothebrainandotherorgans2 Topicalapplicationoffreeradicalscavengerstothebraininhibitsthedevelopmentofpial…  相似文献   

10.
InChina,hepatocellularcarcinoma(HCC)rankssecondincancermortalitysince1990s-InthefieldofHCCtreatment,surgicalresectionremainsthebest,whichincludeslargeHCCresection,smallHCCresection,reresectionofsubclinicalrecurrence,aswellascytoreductionandsequentia…  相似文献   

11.
Chronicperiodontitisisaverycommonoraldisease Sinceitisadifficultdiseasetocure ,itattractstheattentionofmanyresearchers Recentstudiessuggestthatimmunocompetencesubstancespresentinthehumanbodyareimportantfactorsinphysiologicalfunctionanddemonstratethatel…  相似文献   

12.
Objective Toinvestigatetherelationshipbetweenβglucuronidaseandtumordifferentiationandinvasioninhumancolorectalcarcinoma.Methods Theexpressionofβglucuronidaseinhumancolorectalcarcinomatissuewasdeterminedbystreptavidinperoxidaseimmunohistochemicalme…  相似文献   

13.
Fas (CD95)andFasligand (FasL) ,asmembersofTNFfamilies ,aretypeⅠandtypeⅡcellulartransmembraneproteins FasLinducesapoptosisbybindingtoitsreceptorFasonthecellsurface Thisprocessisinvolvedinimmuneresponsetovirus ,tumorcellsandtheregulationoflymphocytehomeostasis…  相似文献   

14.
LiverfibrosisisacommonpathwaytocirrhosisandhasdrawnmuchattentioninrecentyearsInroutinehepatologicalpractice,percutaneousliverbiopsyisthestandardforestablishingthediagnosisofliverfibrosis1 andforguidingandmonitoringtreatmentHowever,thereareacomplicatio…  相似文献   

15.
In 1990 ,Kitagawaetal1 firstfoundthatneuronalcellsinthegerbilhippocampuscoulddevelopresistancetoischemicneuronaldamageafterabriefperiodofreversibleischemia Thisphenomenon ,called“ischemictolerance” ,hasdrawnattentionbecausetheunderstandingofitsmechanismwil…  相似文献   

16.
Itissuggestedthatexcessfreeradicalformationmayoccurinpatientswithschizophrenia14 Whenthenumberoffreeradicalincreases,theenzymesinvolvedinradicalmetabolismmaybeconsequentlyalteredSuperoxidedismutase(SOD)isoneofthescavengingenzymesdetoxifyingsuperoxidera…  相似文献   

17.
ObjectivesToelucidatethetherapeuticmechanismoftopicalcamptothecin(CPT)intreatingpsoriasisandtodetecttheefectsofCPTonkeratinoc...  相似文献   

18.
Investigation of long-term preservation of pancreatic islets   总被引:4,自引:0,他引:4  
PreservationofisolatedisletofLangerhansisanecesaryprocedureforrealizinglargescaleclinicalpancreaticisletgraftingforthetreatme...  相似文献   

19.
Theasexualbloodstageofmalariaparasitesistheonlystageresponsibleforthepathologyofthediseaseandhas,therefore,beenthesubjectofmostofthestudiesonmalariavaccineBasedoninvivopassivetransferofimmunityinhumans,considerableevidenceshaveproventhatIgGconstitut…  相似文献   

20.
Itwasreportedthatinanimaltests,exposuretonhexaneandthinners,particularlythecomponentsethylacetateandxylene,cancausetesticulardamage1Exposuretocarbondisulphideandethyleneglycolethershasbeenlinkedwithinfertility2 Somestudiessuggestthatthereisanassoc…  相似文献   

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