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1.
Quality of life of patients with mild hypertension treated with captopril: a randomized double-blind placebo-controlled clinical trial 总被引:2,自引:0,他引:2
ObjectiveTodeterminethequalityoflife(QOL)ofmildhypertensivepatientstreatedwithcaptoprilascomparedtoplacebo.MethodsThisisarand... 相似文献
2.
Deletion of chromosomes 9p and 17 associated with abnormal expression of p53, p16/MTS1 and p15/MTS2 gene protein in hepatocellular carcinomas 总被引:4,自引:0,他引:4
Hepatocellularcarcinoma (HCC)ranksthirdamongthecausesofcancermortalityinChina ,andabout4 2 5%oftheworld’snewcasesofHCCeachyearoccurinChina 1EpidemiologicstudiesprovideevidencethatinfectionwithhepatitisB (HBV )and/orhepatitisC (HCV ) ,andingestionofaflatoxinBcon… 相似文献
3.
Itisverydificulttoachieveasuccesforscarstenosisofthecervicalesophagusandanastomoticstenosisaftercolonorstomachtranspositionto... 相似文献
4.
The impact of codon 54 variation in intestinal fatty acid binding protein gene on the pathogenesis of diabetes mellitus in Chinese 总被引:3,自引:0,他引:3
Noninsulindependentdiabetesmelitus(NIDDM)isnowconsideredtobeacomplexdiseaseresultingfromgeneticandenvironmentalfactors.Mutat... 相似文献
5.
TheC→TsubstitutionatthepositionofIVS2nt.654(IVS2654C→T,β654),amutationcausingdefectinRNAsplicing,isoneofthemostcommonβtha... 相似文献
6.
Althoughmanyhypothesesofanesthesiahavebeenproposed,includingenhancementofinhibitionandalsodepressionofexcitatorysynaptictransmission,theexactmechanismofactionofgeneralanestheticsonthecentralnervoussystemremainsundefined1 However,specifiedtargetsitesofa… 相似文献
7.
Leishmaniaparasiteinfectionnotonlycausescateoneousandmucosallesions,butalsoviseralLeishmaniasis1 ThestudyindicatedthatLeishmaniainfectioncouldevokeinfectedsubject’simmunesystemandacquiredprotectiveimmunityandinhibitsecondaryLeishmaniainfections2 So… 相似文献
8.
Thec mycproto oncogeneplaysaroleinmanycellularprocesses ,suchasproliferation ,differentiationandapoptosis Itisanearly responsegenenecessaryforcell cycleprogression (G1 Stransition)andactivatesquiescentcellsintothecellcycle (G0 G1transition) Down regulationofc … 相似文献
9.
Superoxide dismutase gene expression and activity in the brain of spontaneously hypertensive rats and normotensive rats 总被引:1,自引:0,他引:1
Membraneabnormalitiesinhumanessentialhypertensionsarewellestablished1 Toxicoxygenmetabolitessuchassuperoxideanionshavebeenimplicatedintissueinjurytothebrainandotherorgans2 Topicalapplicationoffreeradicalscavengerstothebraininhibitsthedevelopmentofpial… 相似文献
10.
Surgical treatment of hepatocellular carcinoma and related basic research with special reference to recurrence and metastasis 总被引:26,自引:0,他引:26
InChina,hepatocellularcarcinoma(HCC)rankssecondincancermortalitysince1990s-InthefieldofHCCtreatment,surgicalresectionremainsthebest,whichincludeslargeHCCresection,smallHCCresection,reresectionofsubclinicalrecurrence,aswellascytoreductionandsequentia… 相似文献
11.
An investigation of immunocompetence substances in normal gingival and period ontitis tissue 总被引:1,自引:0,他引:1
Chronicperiodontitisisaverycommonoraldisease Sinceitisadifficultdiseasetocure ,itattractstheattentionofmanyresearchers Recentstudiessuggestthatimmunocompetencesubstancespresentinthehumanbodyareimportantfactorsinphysiologicalfunctionanddemonstratethatel… 相似文献
12.
Objective Toinvestigatetherelationshipbetweenβglucuronidaseandtumordifferentiationandinvasioninhumancolorectalcarcinoma.Methods Theexpressionofβglucuronidaseinhumancolorectalcarcinomatissuewasdeterminedbystreptavidinperoxidaseimmunohistochemicalme… 相似文献
13.
Factors influencing the expression of Fas and Fas ligand on newborn murine ker atinocytes and fibroblasts 总被引:2,自引:0,他引:2
Fas (CD95)andFasligand (FasL) ,asmembersofTNFfamilies ,aretypeⅠandtypeⅡcellulartransmembraneproteins FasLinducesapoptosisbybindingtoitsreceptorFasonthecellsurface Thisprocessisinvolvedinimmuneresponsetovirus ,tumorcellsandtheregulationoflymphocytehomeostasis… 相似文献
14.
LiverfibrosisisacommonpathwaytocirrhosisandhasdrawnmuchattentioninrecentyearsInroutinehepatologicalpractice,percutaneousliverbiopsyisthestandardforestablishingthediagnosisofliverfibrosis1 andforguidingandmonitoringtreatmentHowever,thereareacomplicatio… 相似文献
15.
Hyperbaric oxygen preconditioning induces neuroprotection against is chemia in transient not permanent middle cerebral artery occlusion rat model 总被引:32,自引:0,他引:32
In 1990 ,Kitagawaetal1 firstfoundthatneuronalcellsinthegerbilhippocampuscoulddevelopresistancetoischemicneuronaldamageafterabriefperiodofreversibleischemia Thisphenomenon ,called“ischemictolerance” ,hasdrawnattentionbecausetheunderstandingofitsmechanismwil… 相似文献
16.
Itissuggestedthatexcessfreeradicalformationmayoccurinpatientswithschizophrenia14 Whenthenumberoffreeradicalincreases,theenzymesinvolvedinradicalmetabolismmaybeconsequentlyalteredSuperoxidedismutase(SOD)isoneofthescavengingenzymesdetoxifyingsuperoxidera… 相似文献
17.
Experimental studies on topoisomerase inhibitor camptothecin as an antipsoriatic agent 总被引:2,自引:0,他引:2
ObjectivesToelucidatethetherapeuticmechanismoftopicalcamptothecin(CPT)intreatingpsoriasisandtodetecttheefectsofCPTonkeratinoc... 相似文献
18.
Investigation of long-term preservation of pancreatic islets 总被引:4,自引:0,他引:4
PreservationofisolatedisletofLangerhansisanecesaryprocedureforrealizinglargescaleclinicalpancreaticisletgraftingforthetreatme... 相似文献
19.
Effects of the configuration of a multi-epitope chimeric malaria DNA vaccine on its antigenicity to mice 总被引:2,自引:0,他引:2
Theasexualbloodstageofmalariaparasitesistheonlystageresponsibleforthepathologyofthediseaseandhas,therefore,beenthesubjectofmostofthestudiesonmalariavaccineBasedoninvivopassivetransferofimmunityinhumans,considerableevidenceshaveproventhatIgGconstitut… 相似文献
20.
Itwasreportedthatinanimaltests,exposuretonhexaneandthinners,particularlythecomponentsethylacetateandxylene,cancausetesticulardamage1Exposuretocarbondisulphideandethyleneglycolethershasbeenlinkedwithinfertility2 Somestudiessuggestthatthereisanassoc… 相似文献