罗丹明类荧光探针进行小分子信标物标记的研究进展

罗丹明类荧光探针基于吡喃型氧杂蒽母体结构,兼具有共轭结构与刚性平面,表现可见光区至近红外光区的长波激发与发射,进行光学性能分析时背景荧光干扰较少、检测过程直观可视,此外,因其结构的可修饰特性,罗丹明具有数量众多的衍生物,在小分子信标物的荧光标记研究中表现良好,具有广泛的应用前景.综述了近年来罗丹明类荧光探针进行改性修饰...     

具有杀虫活性的缩氨基脲类化合物的研究进展

概述了具有杀虫活性的缩氨基脲类化合物的研究进展情况.文中涉及吡唑啉类、茚虫威类似物、氰氟虫腙类似物及其他类别化合物的结构及活性介绍,并对该类化合物的发展趋势和前景作了展望.     

银、氟双元素改性TiO2光催化材料的性能

以多孔泡沫镍为载体,采用水热合成法制备了Ag修饰和Ag-F共改性多孔TiO2光催化材料,用多种方法对其进行了表征,并评价了其对水中罗丹明B的降解性能. 罗丹明B的光催化降解反应符合零级动力学规律,TiO2中主要成分为锐钛矿型纳米TiO2晶体,经500℃煅烧0.5 h后光催化性能提高. Ag修饰TiO2的光催化性能随Ag修饰量的增加先升高后下降,Ag修饰量大于0.6%时,其光催化性能又提高,最佳Ag修饰量为1.2%. 煅烧处理使样品的光催化性能提高,当Ag修饰量为0.8%时,其光催化性能最优. 1.2% Ag和2.0% F共改性的多孔光催化材料的光催化性能远优于单一Ag修饰材料.     

具有农用杀菌活性的砜类衍生物的研究进展

砜类化合物具有良好的杀菌活性,通过结构修饰将不同基团引入到砜结构中,有望创制得到更好杀菌活性的砜类化合物,综述了不同结构特征的砜类化合物及其杀菌活性,并展望了砜类化合物在农药杀菌方面的发展趋势和应用前景。     

糖苷类化合物非水相生物催化结构修饰的研究进展

介绍了非水相生物催化的现状,包括常用催化剂种类如游离酶、固定化酶和全细胞催化剂,常见的非水相催化介质如有机溶剂体系、无溶剂体系、离子液体体系以及超临界流体介质体系,阐述了糖苷类化合物的去糖基化修饰、糖基化修饰、酰化修饰以及甲基化修饰等方法,并叙述了结构修饰对化合物性质的影响,如提高化合物的溶解度、增强化合物的稳定性以及提升化合物的生物活性等,简单介绍了目前糖苷类结构修饰化合物的相关应用。     

双酰胺类化合物在新农药创制中的研究进展

综述了邻二甲酰胺类化合物和邻甲酰氨基苯甲酰胺类化合物,介绍了各自的代表物氟虫双酰胺和氯虫苯甲酰胺以及这两类化合物的类似物,并展望了双酰胺类化合物的研究趋势。     

罗丹明B分子印迹聚合物的制备及分子识别性能研究

以三苯甲烷类碱性染料罗丹明B为模板分子,丙烯酰胺为功能分子,N,N-亚甲基双丙烯酰胺(MBA)为交联剂,采用表面修饰分子印迹法,制备对罗丹明B具有特定亲和选择性的分子印迹聚合物。应用红外光谱对印迹聚合物进行表征,通过静态吸附实验对聚合物的吸附动力学进行分析,采用平衡结合实验评价了分子印迹聚合物的吸附性能。结果表明,采用表面修饰分子印迹法所制备的印迹聚合物对罗丹明B表现出较好的特异吸附,对模板分子最大吸附量值为96μmol/g。     

具有JH活性的含硫氨基甲酸酯类化合物

介绍了昆虫保幼激素类似物的发展状况,评述了具有保幼激素活性的含硫氨基甲酸酯类化合物的合成和生物活性,讨论了昆虫保动激素类似物在害虫防治中的作用及其存在的问题。     

胰岛素结构改造的研究进展

胰岛素是一种由胰腺分泌的激素,一直是治疗Ⅱ型糖尿病的一线药物。由于胰岛素是一种天然的多肽类化合物,因此存在稳定性差、体内代谢快等缺陷。针对这些问题,科研人员一直致力于对胰岛素进行结构改造以开发出新型的胰岛素类抗Ⅱ型糖尿病药物。简述了胰岛素的结构及作用特点,综述了近年来胰岛素结构改造的研究进展,如对胰岛素二硫键的修饰、胰岛素序列的改造、胰岛素肽链N-末端的修饰等,指出了开发高活性、低成本、高稳定性的胰岛素结构改造类似物将是该领域未来发展的主要方向。     

多环芳烃类化合物的合成研究进展

多环芳烃类化合物因具有独特的分子结构以及突出的电子性能,在发光二极管、有机半导体材料、太阳能电池及场效应晶体管中有着极其广泛的应用。为了更好地发挥性能,扩大生产及拓宽应用范围,科研工作者还经常在多环芳烃中引入功能化官能团对其进行修饰。近年来,合成结构新颖、性能诱人的多环芳烃类化合物吸引了国内外众多研究者的青睐。本文选择性地概述了平面型多环芳烃类化合物的研究进展,旨在合成方法上有所突破,使之在新型功能材料领域得到更广泛的应用。     

三元若丹明激光染料荧光寿命研究

利用单光子计数技术测试了新型三元若丹明激光染料在不同溶剂中的荧光寿命、荧光光谱及其寿命的实验数据 .实验表明 ,所研究的三元若丹明染料存在着有效的分子内能量传递过程 ,这些过程使得激光染料的荧光量子效率及光稳定性明显改善 .     

Adsorption and photocatalysis of colour removal from waste water using flyash and sunlight

Adsorption of dyes viz. thionine, eosin Y and rhodamine B on flyash has been investigated as a function of flyash and dye concentrations, contact time and pH. Photodegradation of dyes has been achieved by illuminating the reacting system containing dye and flyash with visible light.     

Process control for thin organic coatings using fluorescence dyes

The fluorescence dyes rhodamine B and auramine O were added to a coating material based on hybrid polymers (ORMOCER^®s) in concentrations of 10 ppm each. The fluorescence intensity of the auramine depends on the curing state of the lacquer while rhodamine is almost insensitive to this variation of the molecular environment. With the combination of both these dyes, the curing state as well as the thickness of the coating can be measured.Due to the low concentration the dyes do not degrade the properties of the lacquer coating.     

层状蛭石有机荧光染料组装超薄膜

基于有机荧光染料的固体团聚或者堆叠导致荧光猝灭、发光和稳定性减弱，采用剥离与超分子组装的方法，制备固体荧光超薄膜发光体。首先通过剪切剥离制备蛭石纳米片，控制其粒径分布在30~300 nm，再通过与有机荧光染料（罗丹明6G和罗丹明B）层层超分子组装的方法，获得蛭石有机无机荧光薄膜。经对比实验发现，不添加蛭石纳米片，无法获得均匀发光的荧光薄膜。蛭石有机无机荧光薄膜的SEM显示，有机荧光染料和蛭石分布均匀，克服有机荧光染料团聚或者堆叠的荧光猝灭，实现荧光亮度可控。     

A microscopical study of the pathway for diffusion of rhodamine B and octadecylrhodamine B into wool fibres*

The pathways for the diffusion of the basic dyes rhodamine B and octadecylrhodamine B into wool under aqueous and non–aqueous dyeing conditions have been investigated. The distribution of each dye within the fibre at various stages of the dyeing process was monitored by fluorescence microscopy. By judicious choice of solvent system and treatment time, the dyes could be directed into different histological components of the fibre. Intercellular diffusion, involving passage of the dye through the cell membrane complex between the cortical cells, was generally the preferred route for penetration of the fibre. The distribution patterns of the two dyes differed markedly and were strongly dependent upon the solvent composition. Whilst selective staining of the cell membrane complex occurred in an anhydrous solvent system, preferential staining of that region of the cell membrane complex associated with the orthocortex resulted when the dyes were applied from aqueous alcohol systems.     

Green-Emitting Rhodamine Dyes for Vital Labeling of Cell Organelles Using STED Super-Resolution Microscopy

Fluorescence microscopy reveals the localization, spatial distribution, and temporal dynamics of the specifically labeled organelles in living cells. Labeling with exogenous conjugates prepared from fluorescent dyes and small molecules (ligands) is an attractive alternative to the use of fluorescent proteins, but proved to be challenging due to insufficient cell-permeability of the probes, unspecific staining, or low dye brightness. We evaluated four green-emitting rhodamine dyes and their conjugates intended for the specific labeling of lysosomes, mitochondria, tubulin, and actin in living cells. The imaging performance of the probes in living human fibroblasts has been studied by using confocal and stimulated emission depletion (STED) super-resolution microscopy with a commercial 595 nm STED laser. Two bright and photostable dyes (LIVE 510 and LIVE 515) provide specific and versatile staining.     

Polydopamine microparticles as redox mediators for catalytic reduction of methylene blue and rhodamine B

Mussel-inspired polydopamine microparticles (PDA MPs) were prepared and found to act as redox mediators for the catalytic reduction of methylene blue and rhodamine B by NaBH₄. The presence of quinone moieties in the PDA MPs rapidly channeled the electrons derived from the electron donor (NaBH₄) to the dyes, resulting in increased decolorization of the dyes.     

多种因素对MIL-101(Cr)选择性吸附水溶液中染料的影响

在多种条件下研究了金属有机框架MIL-101(Cr)对阳离子型染料(亚甲基蓝、罗丹明B)和阴离子型染料(甲基橙、酸性铬蓝K)的吸附性质,主要研究了MIL-101(Cr)对亚甲基蓝和甲基橙的选择性吸附作用。结果表明,中性环境下无论在单组分还是双组分体系中MIL-101(Cr)对阴离子型染料的吸附能力均大于对阳离子型的吸附能力。在pH=3,T=300 K的条件下,选择性系数β可达5.9,但随着pH的增加,选择性系数逐渐降低。相比之下,温度对吸附的选择性影响不大。选择性吸附的机理可以解释为:由于表面带正电荷,MIL-101(Cr)对阴离子型染料产生静电吸引作用;相反,对阳离子型染料的排斥作用而降低了其吸附能力。另外,乙二胺改性提高了MIL-101(Cr)对阴离子型染料的选择吸附性能,而草酸改性降低了选择吸附性。     

Extraction and recovery of rhodamine B,methyl violet and methylene blue from industrial wastewater using D2EHPA as an extractant

The extraction behavior of cationic dyes namely rhodamine B (RB), methyl violet (MV) and methylene blue (MB) from industrial wastewater has been investigated using di-(2-ethylhexyl) phosphoric acid (D2EHPA) in hexane as a carrier. The extraction of cationic dyes increases with decreasing feed phase pH and increasing D2EHPA concentration in organic phase. The stripping percentage of dyes using acetic acid as the stripping agent from loaded D2EHPA was found to increase with increasing acid concentration. 98% stripping efficiency of dyes was achieved with 8.5 mol/L acetic acid solution at an organic:aqueous phase ratio (O/A) of 2:1. Parameters examined include D2EHPA concentration, effect of diluents, effect of pH, effect of initial dye concentration, equilibration time, and various stripping agents, aqueous to organic phase ratio in extraction and organic to aqueous phase ratio in stripping.