胸腔镜治疗老年非小细胞肺癌的疗效及中转开胸指征

目的 探讨电视胸腔镜(VATS)肺叶切除术治疗非小细胞肺癌(NSCLC)的疗效及中转开胸的指征.方法 2007年开始我科采用VATS肺叶切除术治疗的老年NSCLC患者27例,及采用传统开胸肺叶切除术的老年NSCLC患者25例.比较两组的淋巴结清扫数、手术时间、术中出血量、术后置管引流时间及引流量、术后住院天数、术后并发症、住院费用及术后24 h 疼痛NRS评分情况.结果 两组间淋巴结清扫组数无显著差异.VATS组术中出血量、术后住院日数、术后置管时间比传统开胸组略少,而手术时间较开胸组略多,但差异均无统计学意义(均P＞0.05).而VATS组疼痛NRS评分低于开胸组(P＜0.05),术后引流量也低于开胸组(P＜0.05),手术费用高于开胸组(P＜0.05).VATS组术后发生并发症2例(7.4%),需药物控制的心律失常1例,肺内感染1例;开胸组术后发生并发症2例(8.0%),其中需药物控制的心律失常及感染各1例.两组均无死亡病例.VATS组中转开胸4例.结论 VATS肺叶切除术治疗老年NSCLC疗效确切,术后并发症少,值得临床推广.     

胸腔镜在治疗早期非小细胞肺癌的临床效果分析简

目的 分析胸腔镜治疗早期非小细胞肺癌的临床效果.方法 选取我院2011.3-2013.3收治住院经确诊为NSCLC的患者60例作为研究对象,随机分为胸腔镜（VATS）组和胸腔镜辅助小切口（VAMT）肺癌根治术组,观察治疗效果.结果 治疗过程中,VATS组和VAMT组手术时间、术中出血量、清扫淋巴结数目、术后胸腔引流液体积等比较差异无统计学意义,P〉0.05;VATS组术后住院时间及疼痛程度均优于VAMT组,P〈0.05.结论 VATS下肺叶切除加纵隔淋巴结清扫治疗NSCLC疗效较好,患者术后恢复较快,术后疼痛程度较轻,值得临床推广应用.     

胸腔镜在治疗早期非小细胞肺癌的临床效果分析

目的分析胸腔镜治疗早期非小细胞肺癌的临床效果。方法选取我院2011.3~2013.3收治住院经确诊为NSCLC的患者60例作为研究对象,随机分为胸腔镜(VATS)组和胸腔镜辅助小切口(VAMT)肺癌根治术组,观察治疗效果。结果治疗过程中,VATS组和VAMT组手术时间、术中出血量、清扫淋巴结数目、术后胸腔引流液体积等比较差异无统计学意义,P0.05;VATS组术后住院时间及疼痛程度均优于VAMT组,P0.05。结论 VATS下肺叶切除加纵隔淋巴结清扫治疗NSCLC疗效较好,患者术后恢复较快,术后疼痛程度较轻,值得临床推广应用。     

胸腔镜下肺叶切除治疗早期非小细胞肺癌45例的临床分析

目的对比分析胸腔镜肺叶切除术(VATS)与常规开胸肺叶切除术(CT)在治疗早期非小细胞肺癌的优越性。方法收集我科2010年1月至2014年12月所开展的45例胸腔镜肺叶切除术(VATS)与45例传统开胸肺叶切除术(CT)在治疗早期非小细胞肺癌方面做对照研究,就两组术中所用时间,术中出血量、切口长短、淋巴结清扫数目、胸腔引流管保留时间、术后胸腔积液引流量、切口疼痛程度、术后并发症、术后住院天数,以及肿瘤坏死因子(TNF-α)、白介素1β(IL-1β)、C反应蛋白(CRP)指标差异性进行对比分析。结果VATS组中在术中所用时间、切口长度、术中出血量、胸腔引流管保留时间、术后胸腔积液引流量、以及术后住院天数,明显优于CT组,VATS组术后1、3、5天切口疼痛程度、血清TNF-α、IL-1β及CRP水平均明显低于同时间点CT组(P均0.05),但术后并发症及淋巴结清扫数量组间无差异(P均0.05)。结论胸腔镜肺叶切除术在治疗早期非小细胞肺癌中是一种安全有效并且更加微创的手术方式,值得推广。     

全胸腔镜与开胸肺叶切除术对比观察

目的对比观察全胸腔镜肺叶切除术与开胸肺叶切除术的安全性及术后患者生活质量。方法行全胸腔镜肺叶切除术者30例(VATS组),同期行开胸肺叶切除术者30例(开胸组),比较两组手术期、围术期相关指标及术后随访结果。结果两组患者均顺利完成手术,无术中及围手术期死亡。两组手术时间、肺癌患者淋巴结清扫站数、清扫淋巴结数量及住院总费用相近;术中出血量、术后胸液量、胸管保留时间、住院时间和术后患者的生活质量,VATS组优于开胸组,两组相比,P均<0.05。结论全胸腔镜肺叶切除术安全性、手术效果均不逊于开胸手术,且全胸腔镜手术患者围术期痛苦少、恢复快,术后生活质量较高。     

全胸腔镜肺叶切除与开胸肺叶切除治疗非小细胞肺癌临床疗效分析

目的探讨全胸腔镜肺叶切除与开胸肺叶切除治疗非小细胞肺癌(NSCLC)临床疗效分析。方法分析2009年到2011年接受肺叶切除的180例NSCLC患者,其中90例行全胸腔镜肺叶切除术,作为观察组;90例行常规开胸肺叶切除术,作为对照组,对两组患者手术切口长度、手术时间、手术出血量、淋巴结清扫数量、胸引流管放置时间、术后引流总量、切口疼痛程度、术后住院时间以及并发症发生率等指标进行分析。结果治疗组手术切口、手术时间、手术出血量、切口疼痛程度、术后住院时间以及并发症发生率均明显低于对照组,差异有统计学意义(P<0.05)。两组淋巴结清扫数量、胸引流管放置时间以及术后引流总量比较没有统计学意义(P>0.05)。结论全胸腔镜肺叶切除术治疗(NSCLC)安全有效,值得临床推广使用。     

基层医院开展胸腔镜肺叶切除的经验总结

目的总结在基层医院开展胸腔镜(video-assisted thoracic surgery,VATS)肺叶切除手术与传统开胸肺叶切除的临床经验。方法通过分析同时期VATS肺叶切除18例患者以及传统开胸肺叶切除10例患者的临床资料,对比两组患者的住院时间、手术时间、术中出血量、术后拔管天数以及术后并发症发生率。结果两组患者在手术时间、术中出血量、术后拔管天数均无统计学差异(P0.05)。住院时间,VATS组要明显少于传统开胸组(9.9±2.6d VS18.4±7.8d),统计学有明显差异(P0.05)。术后总的并发症发生率,VATS组也要小于传统组(11.1%vs 30%)。结论在基层医院开展早期胸腔镜肺叶手术过程中,VATS肺叶切除术具有传统开胸手术相似的临床效果,且创伤小、住院时间短、术后并发症少等优点。     

胸腔镜下肺叶切除治疗非小细胞肺癌的疗效观察

目的 观察胸腔镜下肺叶切除治疗非小细胞肺癌的临床疗效.方法 选择非小细胞肺癌患者80例,按手术方式不同分为胸腔镜组30例和开胸组50例.观察两组手术时间、术中出血量、术中淋巴结清扫情况、术后并发症、术后引流时间、住院天数、生存率及复发率.结果 所有患者手术顺利,无死亡病例.胸腔镜组手术时间和术中出血量明显低于开胸组（P均＜0.05）.两组局部复发率、并发症发生率及淋巴结清扫情况、术后引流时间、住院天数、术后病理分期比较差异无统计学意义.两组1、2、3年生存率比较差异无统计学意义.进一步对两组病理分期为Ⅰ、Ⅱ期的生存率比较,结果亦无统计学意义.结论 胸腔镜手术治疗非小细胞肺癌的临床效果与开胸手术相当,但其手术时间和术中出血量明显降低,值得临床推广应用.     

胸腔镜下肺叶切除术在非小细胞肺癌患者中的应用效果

目的分析胸腔镜下肺叶切除术在非小细胞肺癌(NSCLC)患者中的应用效果。方法选取2012年3月—2014年1月在重庆市开州区人民医院行肺叶切除术的NSCLC患者96例,根据手术方式分为开胸组40例和胸腔镜组56例。开胸组患者行开胸肺叶切除术,胸腔镜组患者行胸腔镜下肺叶切除术。比较两组患者围术期指标(包括手术时间、术中出血量、术后引流时间、术后镇痛时间、住院时间)、术后30 d并发症发生率及术后3年生存率。结果胸腔镜组患者手术时间、术后引流时间、术后镇痛时间、住院时间短于开胸组,术中出血量少于开胸组(P<0.05)。两组患者总并发症发生率、轻微并发症发生率比较,差异无统计学意义(P>0.05);胸腔镜组患者严重并发症发生率低于开胸组(P<0.05)。两组患者术后3年生存率比较,差异无统计学意义(P>0.05)。结论行胸腔镜下肺叶切除术的NSCLC患者与行开胸肺叶切除术的NSCLC患者3年生存率相近,但其可有效缩短患者手术时间、术后引流时间、术后镇痛时间及住院时间,减少术中出血量,降低术后严重并发症发生风险。     

达芬奇机器人辅助肺段切除术治疗ⅠA期NSCLC的临床疗效分析

目的 比较达芬奇机器人手术(robot-assisted thoracic surgery, RATS)与胸腔镜手术(video-assisted thoracic surgery, VATS)肺段切除术对ⅠA期非小细胞肺癌(non-small cell lung cancer, NSCLC)的临床疗效。方法 选择2018年2月至2021年4月我院收治行肺段切除术IA期NSCLC患者108例,根据手术方式分为RATS组58例和VATS组50例。比较两组手术持续时间、术中出血量、淋巴结清扫数目、淋巴结清扫站数、术后胸腔总引流量、术后引流时间、总住院时间和并发症等。术后随访,比较两组肺癌复发及生存情况,明确两种手术方式对ⅠA期NSCLC治疗有效性差异。结果 RATS组术中总失血量(52.79±14.76) ml、淋巴结清扫数目(16.49±2.88)枚、淋巴结清扫站数(6.58±0.75)组和出院时间(6.23±2.13)d优于VATS组[术中总失血量(87.32±15.47) ml、淋巴结清扫数目(11.07±1.18)枚、淋巴结清扫站数(4.05±0.69)组和出院时间(7.57±2....     

Comparative study of systematic thoracoscopic lymphadenectomy and conventional thoracotomy in resectable non-small cell lung cancer

Objective

To assess the feasibility and safety of the video-assisted thoracoscopy surgery (VATS) systematic lymph node dissection in resectable non-small cell lung cancer (NSCLC).

Methods

The clinical data of patients with NSCLC who underwent VATS or thoracotomy combined with lobectomy and systematic lymphadenectomy from January 2001 to January 2008 were retrospectively analyzed to identify their demographic parameters, number of dissected lymph nodes and postoperative complications.

Results

A total of 5,620 patients were enrolled in this study, with 2,703 in the VATS group, including 1,742 men (64.4%), and 961 women (35.6%), aged 59.5±10.9 years; and 2,917 in the thoracotomy group, including 2,163 men (74.2%), and 754 women (25.8%), aged 58.5±10.4 years. Comparing the VATS with the thoracotomy groups, the mean operative time was 146 vs. 157 min, with a significant difference (P<0.001); and the average blood loss was 162 vs. 267 mL, with a significant difference (P<0.001). Comparing the two groups of patients data, the number of lymph node dissection: 18.03 in the VATS group and 15.07 in the thoracotomy group on average, with a significant difference (P<0.001); postoperative drainage time: 4.5 days in the VATS group and 6.37 days in the thoracotomy group on average, with a significant difference (P<0.001); postoperative hospital stay: 6.5 days in the VATS group and 8.37 days in the thoracotomy group on average, with a significant difference (P<0.001); proportion of postoperative chylothorax: 0.2% (4/2,579) in the VATS group and 0.4% (10/2,799) in the thoracotomy group, without significant difference (P>0.05).

Conclusions

For patients with resectable NSCLC, VATS systematic lymph node dissection is safe and effective with fewer postoperative complications, and significantly faster postoperative recovery compared with traditional open chest surgery.     

单向式胸腔镜肺叶切除与传统开胸手术比较

目的评价单向式胸腔镜肺叶切除术的临床应用效果。方法分析我院单向式胸腔镜肺叶切除术57例和传统开胸肺叶切除手术65例,分别统计手术时间、术中失血量、术后住院时间等方面的差别。结果 122例均手术成功,无围手术期死亡病例。两者在性别、年龄、肿瘤大小、淋巴结清扫数、术后住院时间方面无统计学差异,前者在手术时间、术中失血量、切口疼痛、术后胸腔引流时间、并发症方面优于后者,P<0.05。结论单向式胸腔镜手术是肺癌根治的一种可供选择的有效手段,与传统开胸手术比较有许多优点。     

胸腔镜与传统开胸心脏跳动下房间隔缺损修补的临床效果比较

目的：对比完全胸腔镜与传统开胸手术治疗先天性房间隔缺损（ ASD）的效果。方法 ASD修补术患者30例分为心脏跳动下电视胸腔镜组（15例）和传统开胸组（15例）进行手术。比较两组体外循环时间、完成手术时间、术后拔除气管插管时间、术后引流量、住院时间及外科治疗效果。结果体外循环时间、完成手术时间、术后拔除气管插管时间及外科治疗效果两组比较差异无统计学意义（ P＞0.05）。电视胸腔镜组引流量、住院时间、术后切口疼痛发生率少于或低于传统开胸组,差异有统计学意义（ P＜0.05）。结论胸腔镜具有创伤小、恢复快、疼痛轻等特点,心脏不停跳下完成胸腔镜ASD手术是可行的。     

肺癌切除术后乳糜胸的早期诊断和治疗

目的探讨肺癌切除术后乳糜胸的早期诊断和治疗。方法回顾性分析2009年1月至2013年12月我院胸外科肺癌切除术后并发乳糜胸患者的临床病理资料,并比较常规开胸与胸腔镜手术后乳糜胸的差别。结果 3 479例肺癌切除患者术后并发乳糜胸12例(0.34%,12/3 479),胸腔镜手术组的发生率为0.41%(7/1 719),开胸手术组为0.28%(5/1 760),两者之间未见统计学显著性差异(P0.05)。11例(91.7%)采用保守治疗,1例(8.3%)再次手术行胸导管结扎后,全部恢复顺利。胸腔镜手术组乳糜胸患者的手术时间(207±29.1)min、平均出血量(142.9±60.7)ml、清扫淋巴结数(20.1±5.7)枚、带胸管时间(13.9±4.9)d、住院时间(26.7±5.7)d,与开胸手术组乳糜胸患者的手术时间(192±72.2)min、平均出血量(220.0±109.5)ml、清扫淋巴结数(14.4±4.5)枚、带胸管时间(13.2±7.8)d、住院时间(27.0±8.7)d相比,未见统计学有显著性差异(P0.05)。结论乳靡胸是肺癌术后的一种少见并发症,与手术方式无关,多数可采用保守措施治愈。     

完全胸腔镜在肺癌根治术中的应用

目的讨论完全电视胸腔镜（VATS）在肺癌根治术中的应用。方法分析45例术前临床诊断非小细胞肺癌的患者,应用VATS手术治疗的临床资料。结果45例患者切口长度（5．2±1．1cm）,术后胸腔引流时间（5．4±1．5d）,术后住院时间（7．4±2．4d）,手术时间（145±42min）术中出血量（121±100min）,淋巴结清扫时间（57±25min）切除淋巴结（14±3枚）。患者术后恢复顺利,无严重并发症发生及死亡病例。结论完全电视胸腔镜（VATS）有可能成为非小细胞肺癌患者中可手术患者的更好选择。     

Is major pulmonary resection by video-assisted thoracic surgery an adequate procedure in clinical stage I lung cancer?

OBJECTIVE: Although several studies have shown that video-assisted thoracic surgery (VATS) for major pulmonary resection is less invasive than open thoracotomy, VATS for lung cancer has been performed in only a limited number of institutions. We aimed to review our experience of VATS for major pulmonary resections, and to determine its safety and adequacy in stage I lung cancer. METHODS: Between August 1999 and March 2003, we performed major pulmonary resection by VATS in 106 patients with lung cancer and preoperatively determined clinical stage I disease. We evaluated the number of procedures converted to open thoracotomy and the reasons for conversion, the intraoperative blood loss, interval between surgery and chest tube removal, length of postoperative hospital stay, postoperative complications, mortality rate, prognoses, and patterns of recurrence. RESULTS: We successfully performed VATS in 95 patients, whereas in another 11 patients (10%) conversion to open thoracotomy was required. The operative procedures were lobectomy in 86 patients, segmentectomy in 8 patients, and bilobectomy in 1 patient. In 95 patients who underwent VATS, postoperative complications developed in 9 patients (9%), and 1 patient (1%) died from pneumonia. In the 86 patients without complications, the mean postoperative hospital stay was 7.6 days (range, 4 to 15 days). In a mean follow-up period of 25 months (range, 6 to 48 months) in patients with non-small cell lung cancer (NSCLC), including the one perioperative death, the 3-year survival rate was 93% in 82 patients with clinical stage I disease, and 97% in 68 patients with pathologic stage I disease. The 3-year disease-free survival rate was 79% in patients with clinical stage I disease, and 89% in patients with pathologic stage I disease. Local recurrence was observed in six patients (6%): recurrence in mediastinal lymph nodes in five patients, and in the bronchial stump in one patient. CONCLUSIONS: Major pulmonary resection by VATS is acceptable in view of its low perioperative mortality and morbidity, and is an adequate procedure for the achievement of local control and good prognosis in patients with clinical stage I NSCLC.     

Video-assisted thoracic surgery for pulmonary sequestration: a safe alternative procedure

Background

Pulmonary sequestration (PS), a rare congenital anatomic anomaly of the lung, is usually treated through resection by a conventional thoracotomy procedure. The efficacy and safety of video-assisted thoracic surgery (VATS) in PS treatment has seldom been evaluated. To address this research gap, we assessed the efficacy and safety of VATS in the treatment of PS in a large Chinese cohort.

Methods

We retrospectively reviewed 58 patients with PS who had undergone surgical resection in our department between January 2003 and April 2014. Of these patients, 42 (72.4%) underwent thoracotomy, and 16 (27.6%) underwent attempted VATS resection. Clinical and demographic data, including patients’ age, sex, complaints, sequestration characteristics, approach and procedures, operative time, resection range, blood loss, drainage volume, chest tube duration, hospital stay, and complications were collected, in addition to short-term follow-up data.

Results

Of the 58 participating patients, 55 accepted anatomic lobectomy, 2 accepted wedge resection, and 1 accepted left lower lobectomy combined with lingular segmentectomy. All lesions were located in the lower lobe, with 1–4 aberrant arteries, except one right upper lobe sequestration. Three cases (18.8%) in the VATS group were converted to thoracotomy because of dense adhesion (n=1), hilar fusion (n=1), or bleeding (n=1). No significant differences in operative time, postoperative hospital stay, or perioperative complications were observed between the VATS and thoracotomy groups, although the VATS patients had less blood loss (P=0.032), a greater drainage volume (P=0.001), and a longer chest tube duration (P=0.001) than their thoracotomy counterparts.

Conclusions

VATS is a viable alternative procedure for PS in some patients. Simple sequestration without a thoracic cavity or hilum adhesion is a good indication for VATS resection, particularly for VATS anatomic lobectomy. Thoracic cavity and hilum adhesion remain a challenge for VATS.