中心静脉导管引流胸腔积液治疗结核性胸膜炎24例疗效观察

目的探讨结核性胸膜炎清除胸腔积液的方法。方法选择结核性胸膜炎46例,随机分为治疗组和对照组,治疗组24例采用中心静脉导管及其组件行引流胸腔积液,对照组22例采用常规胸穿抽液,对两组患者的胸液消失时间、不良反应、遗留胸膜增厚粘连及包裹性积液等进行统计比较分析。结果治疗组胸液消失时间(5.0±1.1)天、胸膜反应1例、遗留胸膜增厚粘连及包裹性积液1例,对照组胸液消失时间(14.3±2.2)天、胸膜反应6例、遗留胸膜增厚粘连及包裹性积液9例,两组比较有显著性差异(P<0.05)。结论中心静脉导管及其组件行引流胸腔积液治疗结核性胸膜炎的方法比较方便、安全、胸水消失时间短、引起不良反应和胸膜增厚粘连后遗症较少。     

类风湿关节炎胸膜受累的临床特点分析

目的提高对于类风湿关节炎(RA)胸膜受累的认识。方法回顾分析RA住院患者胸膜受累的临床特点。结果 248例RA患者中29例胸膜受累,5例胸膜增厚,24例出现胸腔积液;其中18例少量胸腔积液,无症状,无特殊治疗;另外6例中等量胸腔积液,有呼吸困难的症状,予胸腔穿刺引流,胸腔积液为渗出液;4例RA相关,激素治疗后胸腔积液吸收;1例继发结核性胸膜炎,抗结核后好转;1例肺炎旁胸腔积液,抗感染后好转。结论 RA患者可出现胸腔积液或胸膜增厚,一般无症状,无需特殊处理。但胸腔积液明显时,需要排除细菌、结核感染及肿瘤等,胸腔穿刺引流和激素等治疗可缓解症状,继发细菌和结核等感染需要相应的抗感染治疗。     

中心静脉导管胸腔闭式引流联合腔内注射治疗结核性胸腔积液的临床疗效探讨

目的：探讨中心静脉导管胸腔闭式引流联合腔内注射治疗结核性胸腔积液的临床疗效。方法筛选2014年1月-2015年1月该院收治的结核性胸膜炎患者98例,作为研究对象。采用随机数表法将其分为对照组与治疗组,其中对照组患者采取常规胸腔穿刺抽液治疗,隔日抽液1次;治疗组患者接受中心静脉导管胸腔闭式引流联合腔内注射20 U、生理盐水50 mL进行治疗,记录两组患者引流胸液容量、胸水吸收时间、胸膜增厚程度等指标并进行比较。结果引流胸液容量治疗组(1488±237)mL,对照组(1032±241)mL(t=17.355,P=0.015);胸水吸收时间治疗组(15.7±2.5)d,对照组(24.1±3.5)d (t=4.165,P=0.021);血性胸水发生率治疗组2.04%,对照组8.16%(χ2=2.024,P=0.018);差异具有统计学意义;而胸膜增厚率治疗组4.08%,对照组12.24%(χ2=2.271,P=0.134);胸膜反应发生率治疗组2.04%,对照组8.16%(χ2=2.024,P=0.181)差异无统计学意义。结论采用中心静脉导管胸腔闭式引流联合腔内注射治疗结核性胸腔积液具有较好的疗效,胸腔积液引流量较大并且胸水吸收时间较快,并发症发生率较低,具有临床应用及推广价值。     

胸腔闭式引流和间段抽液治疗胸腔积液疗效对照

目的：说明胸腔闭式引流较胸穿抽液治疗大量胸腔积液的优越性；方法：58例患者分为行胸腔闭式引流30例，胸穿抽液28例，观察抽掖量、不良反应发生率、平均胸水消失天数、胸膜增厚率。结果：胸腔闭式引流治疗大量胸腔积液所需时间短、不良反应少、胸膜增厚率低。结论：胸腔闭式引流术优于常规胸穿抽液。     

导管引流并尿激酶注入治疗糖尿病并结核性胸膜炎15例报道

目的探讨中心静脉导管胸腔内置入引流并配合负压吸引、尿激酶注入治疗糖尿病并结核渗出性胸膜炎的疗效.方法将29例糖尿病合并结核性胸膜炎患者随机分为2组,15例胸腔内置入中心静脉导管引流,胸液排尽后注入尿激酶10万u,封管12h后负压吸引,如此反复.14例每周抽液3次.观察两组患者体温、胸液吸收时间和并发症.结果置管组体温恢复正常、胸液吸收时间明显短于抽液组(P＜0.01).置管组胸膜较前增厚2/15例;抽液组10/14例,形成包裹性积液3例.结论中心静脉导管胸腔内置入引流,配合负压吸引、尿激酶注入治疗糖尿病并结核性胸膜炎,能明显减轻结核中毒症状,缩短胸液吸收时间,减轻胸膜肥厚与粘连,防止包裹性胸腔积液.     

胸腔积液降钙素原测定对肺炎旁胸腔积液分期的评价价值

目的 评价胸腔积液降钙素原(PCT)水平在肺炎旁性胸腔积液分期诊断中的价值.方法 42例肺炎旁性胸腔积液患者分为两组:单纯肺炎旁胸腔积液(UCPE)28例、复杂性肺炎旁胸腔积液(CPE)14例,检测两组患者血及胸腔积液中PCT水平.并将19例漏出液患者作为对照组.结果 单纯肺炎旁胸腔积液PCT均值为0.3 ng/ml,复杂性肺炎旁胸腔积液PCT均值为 2.9 ng/ml,两者比较差异有统计学意义(P＜0.01).但两组间血清PCT水平比较差异无统计学意义(P＞0.05).在胸腔积液PCT值大于0.5 ng/ml时被认为可胸腔闭式引流或胸腔内尿激酶腔内注入或建议胸腔镜治疗(敏感度为91.5%,特异度为87.9%).结论 胸腔积液中PCT测定有助于肺炎旁胸腔积液的分期及指导治疗.     

结核性胸腔积液一次性胸腔引流与常规抽液的临床比较

目的：探讨结核性胸腔积液一次性持续胸腔引流与常规抽液的临床治疗作用。方法：46例确诊为中等量以上积液的结核性胸膜炎患者随机分为两组,各23例,在应用全身化疗的基础上,治疗组采用一次性水封瓶持续引流胸水,对照组作常规抽液治疗。结果：治疗组未发现包裹性积液,仅出现1例胸膜增厚,7天内退热达91.3%。平均退热6.1天,中毒症状改善快;对照组中出现脑膜增厚,包裹性积液共12例,占52.2%,7天内退热仅占56.5%,平均退热8.7天。结论：一次性持续胸腔引流中等量以上积液的结核性胸膜炎,可减少胸腔粘连增厚及包裹性积液,减轻中毒症状,临床效果良好。     

中心静脉导管引流胸腔积液疗效观察

目的:探讨结核性胸膜炎治疗方法。方法:所有病人均应用2 HRZE(S)/4 HR方案抗痨治疗,中毒症状较重者辅以激素治疗,选择30例,采用中心静脉导管引流胸腔积液,对照组28例按照常规方式行胸腔穿刺抽液,对2组病人胸液消失时间,产生胸膜增厚的情况进行统计,分析对比。结果:引流组与抽液组相比,穿刺次数明显减少,胸水消失时间明显缩短,治疗组<10天,对照组15~30天。引流组无并发症发生,后遗胸膜增厚明显少于对照组。结论:中心静脉导管引流胸腔积液治疗结核性胸腔积液的方法比较方便,胸水消失时间短、安全,患者痛苦小,疗效满意,适合在临床上推广应用。     

静滴式引流术在结核性胸腔积液中的临床应用

目的:探讨结核性胸腔积液的治疗方法。方法:在全身规则抗结核治疗下,将76例结核性胸腔积液患者随机分为两组,治疗组37例给予静滴式引流,常规组39例给予胸腔穿刺抽水。结果:治疗组胸水完全吸收时间3~4天平均(6.6±3.4)天,常规组7~35天平均(17.4±9.0)天(P<0.01)。发生胸膜肥厚粘连治疗组3例(8.1%),对照组13例(13.3%)(P<0.01),胸水消失时间缩短,肺功能改善。引流组抽液次数平均1.1±0.3次;常规组平均抽液次数2.9±2.2次,两组比较差异具有显著性(P<0.01)。引流组无1例出现并发症,常规组4例出现少量气胸,1例出现胸液感染。结论:静滴式引流术对结核性胸腔积液的治疗安全、方便、有效率高,值得临床推广。     

微导管引流结合丹参注射液用于结核性胸腔积液的疗效观察

目的:探讨微导管闭式引流结合丹参注射液治疗结核性胸腔积液的临床疗效。方法:60例中量以上积液的结核性胸膜炎病例随机分为A组和B组各30例,A组胸腔置管引流并静脉滴注丹参注射液;B组单纯置管引流。结果:A组胸液引流量中位数为1 600 ml,平均胸液消失时间(6.1±1.2)d,2个月末胸膜增厚2例(6.6%);B组胸液引流量中位数为1 480 ml,平均胸液消失时间(6.8±2.2)d,2个月末胸膜增厚7例(23.3%)。结论:微导管引流结合丹参注射液治疗结核性渗出性胸腔积液能显着减少胸膜增厚与粘连,从而防止了胸廓变形及肺功能的损失。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.