铸造Herbst矫治器的制作与应用

目的：探讨铸造Herbst矫治器的制作和临床应用。方法：介绍铸造Herbst矫治器的制作步骤和临床应用。结果：铸造Herbst矫治器增加了支抗部分的强度,能够达到临床应用要求。结论：铸造Herbst矫治器是一种能够较好地适用于临床要求的矫治器。     

Herbst矫治器对下颌后缩患者颞下颌关节改建的研究进展

本文综述了Herbst矫治器对安氏Ⅱ类下颌后缩患者颞下颌关节（TMJ）的改建,包括Herbst矫治器对髁突和关节窝的生长改建以及矫治后髁突在关节窝中位置的变化,并探讨了Herbst矫治器的远期疗效。有利于临床医生正确理解Herbst矫治器与TMJ改建的关系,从而更好的指导临床应用。     

Herbst矫治器与头帽肌激动器矫治骨性安氏Ⅱ类错的比较研究

目的对比研究头帽Activator与Herbst矫治器治疗骨性安氏Ⅱ类错的机理.方法应用Pancherz设计的Herbst矫治器及Van beek设计的Activator治疗Ⅱ类错 ,以X线头影测量方法评价疗效.结果头帽Activator对上颌生长抑制作用强于Herbst矫治器,而Herbst矫治器刺激下颌生长尤其是水平向生长效果优于头帽Activator;头帽Activator内收压入上前牙效果显著;而Herbst矫治器压低下前牙较为明显.结论头帽Activator更适于矫治上颌矢状及垂直向发育过度的Ⅱ类错 ,Herbst矫治器适于矫治下颌发育不足的Ⅱ类错 .     

Herbst矫治器与头帽肌激动器矫治骨性安氏Ⅱ类错He的比较研究

目的对比研究头帽Activator与Herbst矫治器治疗骨性安氏Ⅱ类错的机理.方法应用Pancherz设计的Herbst矫治器及Vanbeek设计的Activator治疗Ⅱ类错,以X线头影测量方法评价疗效.结果头帽Activator对上颌生长抑制作用强于Herbst矫治器,而Herbst矫治器刺激下颌生长尤其是水平向生长效果优于头帽Activator;头帽Activator内收压入上前牙效果显著;而Herbst矫治器压低下前牙较为明显.结论头帽Activator更适于矫治上颌矢状及垂直向发育过度的Ⅱ类错,Herbst矫治器适于矫治下颌发育不足的Ⅱ类错.     

颞下颌关节-下颌骨-Herbst矫治器系统三维有限元模型的建立

目的 建立“颞下颌关节-下颌骨-Herbst矫治器系统”的三维有限元模型，为模拟Herbst矫治器工作状态，进一步探讨Herbst矫治器矫治机理奠定基础。方法 采用CT扫描技术，以处于青春生长高峰期、Ⅱ类骨性错He的儿童的颅面骨作标本，以及使用图形数字化仪等方法，建立包括完整天然牙列和颞颌关节的下颌骨三维正交各向异性有限元模型，在此模型上增加Herbst矫治器，模拟临床上Herbst矫治器的工作状态。结果建立了“颞下颌关节-下颌骨-Herbst矫治器系统”的三维正交各向异性有限元模型，提高了模型的相似性，确保实验结果的准确性。结论 该模型有较好的生物力学相似性和几何相似性，为研究Herbst矫治器的矫治机理，提供了有利的条件，使实验结果更真实、可靠。     

Herbst矫治器支抗带环断裂原因分析及改良

目的 分析传统的Herbst矫治器支抗带环在矫治过程中断裂原因。并提出其改良措施。以利于临床工作需要。方法 在临床上选择20名安氏Ⅱ类1分类下颌后缩小童,随机分为两组,分别采用传统和改良支抗设计的Herbst矫治器进行矫治,于戴矫治器后第1周、第2周、第3周及第4周复诊,检查口内矫治器的固位情况,记录带环的断裂数及断裂部位。结果 传统的Herbst矫治器,上颌第一磨牙的近中轴面及下颌第一前磨牙的远中生全冠的损坏。结论 Herbst短程治器的传统支抗带环容易在应力集中区断裂,而改良的Herbst矫治器的支抗设计较好地弥补了这一不足,且临床矫治效果显著。     

安氏Ⅱ1类错(牙合)下颌后缩儿童经 Herbst 矫治器治疗后的肌电研究

咀嚼肌群的平衡在错畸形的发生、发展与矫治过程中起着重要作用.在应用Herbst矫治器时,可通过套管装置使下颌前移,以改善口颌系统肌群的功能状态;反过来又应用肌张力刺激颌骨做适应性改建,以改善颌骨的矢状不调.国外应用肌电图评价Herbst 矫治器疗效的研究较少[1,2],国内尚未见报道.本项实验拟从功能角度探讨Herbst矫治器治疗时咀嚼肌功能活动的规律,从而分析 Herbst 矫治器作用机理,为临床治疗提供理论依据.     

Herbst矫治器治疗与颞下颌关节改建

本文综述了使用Herbst矫治器对颞下颌关节(TMJ)的髁突、关节窝和关节盘的影响,并探讨了使用Herbst矫治器是否会导致颞下颌关节紊乱(TMD)的问题。这有利于正畸医生正确理解功能性矫治器与TMJ的关系,以指导选择矫治时机和适应证。     

下颌前伸矫治器和Herbst矫治器治疗AngleⅡ类错的对比研究

目的 :比较下颌前伸矫治器 (MandibularProtractionAppliance ,MPA)和Herbst矫治器对AngleⅡ类错牙合的治疗效果。方法 :选择 2 6例AngleⅡ类错牙合病人 ,男 14例 ,女 12例 ,最大 13岁 ,最小 10岁。X线头影测量显示主要为下颌后缩及轻微上颌前突 ,手腕片显示为生长发育高峰期。将这些病人分成两组 ,一组用下颌前伸矫治器治疗 (MPA组 ) ,另一组用Herbst矫治器进行治疗 (HA组 )。功能矫治结束时 ,两组病例均摄X线头颅定位侧位片 ,由专人定点、测量 ,并进行统计学分析。结果 :X线头影测量结果显示两组病例中Co -Pg、Go -Pg及Co -Go均增大 ,其变化量经统计学检验差异无显著性意义 ,表明下颌前伸矫治器及Herbst矫治器均能促进下颌骨生长 ,尤其是下颌升支的生长 ;SNB、ANB、U1-L1、U1-NL及L1-MP的变化量经过统计学检验差异有显著性意义 ,说明下颌前伸矫治器和Herbst矫治器都能有效矫治AngleⅡ类错牙合颌骨矢状关系不调 ,尤其是前者更有效 ,而Herbst矫治器易引起支抗丢失 ,即易使上颌前牙舌向倾斜、下颌前牙唇倾。结论 :下颌前伸矫治器和Herbst矫治器治疗早期AngleⅡ类错牙合均可取得明显的骨胳改变 ,但前者治疗效果更好     

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目的    探讨改良式Herbst 矫治器矫治安氏Ⅱ类下颌后缩伴上牙弓狭窄患者的临床疗效。方法    2004—2009年在南昌大学口腔医院正畸科采用改良式Herbst矫治器治疗11例安氏Ⅱ类下颌后缩伴上牙弓狭窄患者,通过矫治前后头影片的测量对比,分析该矫治器的疗效。结果    经改良式Herbst矫治器治疗6～8个月后,11例患者的下颌均明显前移,上下牙弓协调,下颌后缩面型显著改善。结论    改良式Herbst矫治器能有效地矫治安氏Ⅱ类下颌后缩伴上牙弓狭窄的患者。     

Oral cancer: molecular technologies for risk assessment and diagnosis

Purpose: The effective biomarkers related to diagnosis, metastasis, drug resistance and irradiation sensitivity of oral cancers will help the pathologist and oncologist to determine the molecular taxonomy diagnosis and design the individualization treatment for the patients with oral cancers.     

柠檬精油对牙周致病菌抑制作用及其安全性初步研究

目的:探讨柠檬精油对牙周致病菌的体外抗菌活性及对细胞增殖的影响。方法:采用微量液体稀释法测定柠檬精油对Pg、Fn、Aa、Pi的最小抑菌浓度(minimal inhibitory concentration,MIC)及最小杀菌浓度(minimum bactericidal concentration,MBC);以较低浓度的MIC为标准稀释LEO作为实验组,采用MTT法测定柠檬精油对HUVECs的毒性作用,明确抑菌浓度下LEO的安全性。结果:柠檬精油对牙周主要致病菌均有抑菌作用,Pg、Fn、Aa、Pi的MIC分别是9.0 g/L、4.5 g/L、4.5 g/L、9.0 g/L,Aa、Fn的 MBC是9.0 g/L,Pg、Pi的MBC未测得。1/2MIC、1/20MIC浓度的LEO能够抑制人脐静脉内皮细胞的生长,而低于1/200MIC浓度的LEO则对人脐静脉内皮细胞的生长没有影响,其中1/200MIC浓度的LEO作用明显优于0.02%的CHX。结论:体外环境中,柠檬精油对牙周致病菌Pg、Fn、Aa、Pi具有抗菌活性,低浓度应用对机体相对安全。     

Stimulated whole saliva components in children with Down syndrome

The authors report on the components of stimulated whole saliva from children with Down syndrome—including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6–10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using ortho-dianisidine.
No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.     

Computer-assisted planning for maxillofacial prosthodontic rehabilitation

Computerized tomography (CT) planning and the use of CT derived surgical templates for implant placement have shown promise for restoring function within months after surgical reconstruction of acquired post-oncologic defects.     

牙髓再生的研究现状

目前,根管治疗术在临床上已得到了广泛的应用并成功的保存了患牙,但其仍有许多术后并发症。随着组织工程技术在口腔领域的应用,构建一种组织工程化牙髓进行牙髓-牙本质复合体的再生治疗成为可能。近年来国内外已有很多关于牙髓再生的研究,并且已经取得了一定成果。本文将对目前国内外牙髓再生的研究进展现状作一综述。     

Effect of Pingyangmycin on human venous malformation endothelial cells

Purpose: Venous malformations are common vascular anomalies with a propensity of the head and neck. Intralesional injection of Pingyangmycin (PYM, bleomycin A5 hydrochloride) is a widely used sclerotherapy method for the treatment of venous malformation.     

Clinical and pathological aspects on some odontogenic tumors

Odontogenic tumors constitute a very diverse group of lesions that reflects the complex processes of odontogenesis. Controversies over their classification/subtyping, terminology and diagnosis have been persisted, which has direct bearings on therapeutic and/or prognostic implications.     

Can you be too old for oral implants? An update on ageing and plasticity in the oro‐facial sensorimotor system

This review focuses on the capacity of the brain for plasticity and the utility and efficacy of oral implants in helping to restore oro‐facial sensorimotor functions, especially in elderly patients. The review first outlines the components of the oro‐facial sensorimotor system which encompasses both oro‐facial tissues and a number of brain regions. One such region is the sensorimotor cortex that controls the activity of the numerous oro‐facial skeletal muscles. These muscles are involved in a number of functions including reflexes and the more complex sensorimotor functions of mastication, swallowing and speech. The review outlines the use by the brain of sensory inputs from oro‐facial receptors in order to provide for exquisite sensorimotor control of the activity of the oro‐facial muscles. It highlights the role in this sensorimotor control played by periodontal mechanoreceptors and their sensory inputs to the brain, and how oral implants in concert with the plastic capacity of the brain may, at least in part, compensate for reduced sensorimotor functioning when teeth are lost. It outlines findings of ageing‐related decrements in oro‐facial sensorimotor functions and control. The changes in oro‐facial tissues and the brain that underlie these ageing‐related functional alterations are also considered, along with adaptive and compensatory processes that utilise the brain's capacity for plasticity. The review also notes the evidence t hat rehabilitation that incorporates adjunctive approaches such as sensorimotor training paradigms in addition to oral prostheses such as implants may enhance these processes and help maintain or facilitate recovery of sensorimotor functioning in the elderly.     

Tumor microenvironment in oral cancer: novel approaches for immunotherapy

Squamous cell carcinoma of the head and neck (SCCHN), which arises from the squamous mucosal epithelium of the oral cavity, pharynx and larynx, is a major health problem in the US and other parts of the world, especially in developing countries.