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A Rapid,Highly Sensitive and Selective Phosgene Sensor Based on 5,6-Pinenepyridine |
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| Authors: | Dr Atena B Solea Dr Christophe Curty Prof?Dr Katharina M Fromm Prof?Dr Christophe Allemann Prof?Dr Olimpia Mamula Steiner |
| Affiliation: | 1. Haute école d'ingénierie et d'architecture, HEIA-FR, University of Applied Sciences of Western Switzerland, HES-SO, Pérolles 80, CH-1705 Fribourg, Switzerland
Department of Chemistry, University of Fribourg, Chemin du Musée 9, 1700 Fribourg, Switzerland Contribution: Conceptualization (equal), ?Investigation (lead), Methodology (equal), Validation (equal), Writing - original draft (lead), Writing - review & editing (equal);2. Spiez Laboratory, Austrasse, 3700 Spiez, Switzerland Contribution: Formal analysis (supporting), Methodology (supporting), Writing - review & editing (supporting);3. Department of Chemistry, University of Fribourg, Chemin du Musée 9, 1700 Fribourg, Switzerland Contribution: ?Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (supporting), Validation (supporting), Writing - review & editing (supporting);4. Haute école d'ingénierie et d'architecture, HEIA-FR, University of Applied Sciences of Western Switzerland, HES-SO, Pérolles 80, CH-1705 Fribourg, Switzerland |
| Abstract: | The toxicity of phosgene (COCl2) combined with its extensive use as a reactant and building block in the chemical industry make its fast and accurate detection a prerequisite. We have developed a carboxylic derivative of 5,6-pinenepyridine which is able to act as colorimetric and fluorimetric sensor for phosgene in air and solution. For the first time, the formation of a pyrido-2,1-a]isoindolone was used for this purpose. In solution, the sensing reaction is extremely fast (under 5 s), selective and highly sensitive, with a limit of detection (LOD) of 9.7 nM/0.8 ppb. When fixed on a solid support, the sensor is able to detect the presence of gaseous phosgene down to concentrations of 0.1 ppm, one of the lowest values reported to date. |
| Keywords: | colorimetric sensor fluorescent probe gas sensing paper test strips phosgene |
