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离子液体的毒性
引用本文:柯明,周爱国,宋昭峥,蒋庆哲.离子液体的毒性[J].化学进展,2007,19(5):671-679.
作者姓名:柯明  周爱国  宋昭峥  蒋庆哲
作者单位:中国石油大学 重质油国家重点实验室 北京 102249
摘    要:离子液体因其特有的物化性质受到越来越多的关注,并被认为是环境友好的"绿色产品"。但是有关离子液体的潜在毒性一直被人们所忽视,直到最近才有少量报道。本文综述了离子液体毒性研究的相关情况:详细介绍了离子液体毒性研究的各种方法及优缺点;离子液体对各类生物的急性毒性和慢性毒性;离子液体的各部分组成,尤其是阳离子核种类、取代烷基碳链长度和阴离子种类对离子液体毒性的影响情况,以及SAR理论在离子液体毒性研究中的应用情况。在此基础上提出今后离子液体毒性研究的发展方向。

关 键 词:离子液体  急性毒性  慢性毒性  结构—活性相关  
文章编号:1005-281X(2007)05-0671-09
收稿时间:2006-07
修稿时间:2006-09

Toxicity of Ionic Liquids
Ke Ming,Zhou Aiguo,Song Zhaozheng,Jiang Qingzhe.Toxicity of Ionic Liquids[J].Progress in Chemistry,2007,19(5):671-679.
Authors:Ke Ming  Zhou Aiguo  Song Zhaozheng  Jiang Qingzhe
Affiliation:State Key Laboratory of Heavy Oil Processing,China University of Petroleum,Beijing 102249, China
Abstract:Ionic liquids are gaining increasing interest due to their physical and chemical characteristics.They are also considered sustainable "Green Product".But the potential toxicity of ionic liquids has been neglected,and few toxicological data of ionic liquids are available until now.This review presents the recent reports on the toxicity of ionic liquids from the following aspects: toxicity testing methods,acute and chronic toxicity on organisms,toxicity influenced by the substructures of ionic liquids,the application of the structure-activity relationship theory in the research of the toxicity of ionic liquids.The future research of the toxicity of ionic liquids is also approached.
Keywords:ionic liquids(ILs)  acute toxicity  chronic toxicity  structure-activity relationships(SAR)
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