Asymmetric Syntheses IV: Enantioselective Synthesis of (R)-Benzylic Amines Via Alkylation of D-Camphor Ketimine |
| |
Authors: | Jiang Yaozhong Liu Guilan Liu Jinchu Zhou Changyou Chengdu |
| |
Affiliation: | Institute of Organic Chemistry, Academia Sinica , Chengdu, P.R. China |
| |
Abstract: | An efficient asymmetric synthesis of (R)-benzylic amines in optical purity 36–90% had been achieved by alkylation of a chiral ketimine prepared from D-camphor and benzylamine. Diastereoselectivity in the alkylation is dependent on the alkyl halides. |
| |
Keywords: | |
|
|