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磁共振弥散成像在弥漫性轴突损伤诊断中的应用
引用本文:乔梁,王汉东. 磁共振弥散成像在弥漫性轴突损伤诊断中的应用[J]. 医学研究生学报, 2007, 20(10): 1108-1111
作者姓名:乔梁  王汉东
作者单位:1. 南京军区南京总医院,神经外科,江苏南京,210002
2. 南京大学医学院临床学院,神经外科,江苏南京,210002
基金项目:南京军区总医院科研项目
摘    要:磁共振弥散成像是通过水分子弥散差异成像,反映水分子弥散运动状态。由于成像原理不同于传统磁共振,故弥散成像对中枢神经纤维束的解剖结构改变较为敏感,从而成为弥漫性轴突损伤诊断的重要技术。弥散加权成像能通过突出弥散效应显示损伤灶;弥散张量成像能反映各向异性矢量,更加敏感地显示损伤灶,并可通过神经纤维束成像显示轴突损伤。弥散成像不仅提高了弥漫性轴突损伤的诊断,还有利于判断伤情及预后。该作者对以上问题作一综述。

关 键 词:弥漫性轴突损伤  弥散加权成像  弥散张量成像  神经纤维束成像
文章编号:1008-8199(2007)10-1108-04
收稿时间:2006-03-21
修稿时间:2006-05-09

Application of MR diffusion imaging to the diagnosis of diffuse axonal injury
QIAO Liang,WANG Han-dong. Application of MR diffusion imaging to the diagnosis of diffuse axonal injury[J]. Bulletin of Medical Postgraduate, 2007, 20(10): 1108-1111
Authors:QIAO Liang  WANG Han-dong
Affiliation:Department of Neurosurgery, Nanjing General Hospital of Nanjing Military Command, PLA, School of Medicine, Nanjing University, Nanfing 210002, Jiangsu, China
Abstract:Magnetic resonance diffusion imaging contrasts by water molecule diffusion,reflecting water diffusion status.Owing to the unique mechanism,diffusion imaging is sensitive to anatomic alteration of fiber tract and becomes an important technique in the detection of diffuse axonal injury.Diffusion-weighted imaging shows DAI lesion via emphasizing diffusion composition,diffusion tensor imaging is more sensitive to diffusion anisotropy of the lesion,and fiber tractography can directly demonstrate fiber disruption.MR-diffusion imaging not only improves conspicuity of DAI,but also has grading and prognostic value.
Keywords:Diffuse axonal injury  Diffusion weighted imaging  Diffusion tensor imaging  Fiber tractography
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