| 硼基亲和层析介质的合成及其应用研究 I.基质的合成及孔结构 |
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| 引用本文： | 宁方红,刘坐镇,诸蓓艳,刘勤凤,邬行彦,王彬芳.硼基亲和层析介质的合成及其应用研究 I.基质的合成及孔结构[J].医学教育探索,1998(5). |
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| 作者姓名： | 宁方红 刘坐镇 诸蓓艳 刘勤凤 邬行彦 王彬芳 |
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| 作者单位： | 华东理工大学生物反应器工程国家重点实验室，华东理工大学高分子材料系 |
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| 摘 要： | 以甲基丙烯酸缩水甘油酯和二甲基丙烯酸乙二醇酯为原料，合成了大孔树脂，并研究了交联度、混合致孔剂用量和配比对其孔结构的影响。该树脂与间氨基苯硼酸偶联，制得硼基－聚甲基丙烯酸缩水甘油酯共价亲和层析介质，介质的硼基偶联量可达１．０３６ｍｍｏｌ／ｇ。
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| 关 键 词： | 甲基丙烯酸缩水甘油酯 二甲基丙烯酸乙二醇酯 间氨基苯硼酸 共价亲和层析 |
Synthesis of the Media for the Boronate Affinity Choromatographic and Their ApplicationsI. Studied on the Synthesis and Structure of the Matrix |
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| Ning Fanghong,Liu Zuozhen,Zu Peiyan,Liu Qinfeng,Wu Xingyan and Wang Bingfang.Synthesis of the Media for the Boronate Affinity Choromatographic and Their ApplicationsI. Studied on the Synthesis and Structure of the Matrix[J].Researches in Medical Education,1998(5). |
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| Authors: | Ning Fanghong Liu Zuozhen Zu Peiyan Liu Qinfeng Wu Xingyan and Wang Bingfang |
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| Abstract: | The macroreticular resin was preparted by the copolymerization of glycidyl methacrylate (GMA) with ethylene dimethacrylate(EDMA) and its pore structure was determined. The effects of the ammount of crosslinking degree and the amount as well as proportion of the mixed diluent on the pore structure were also investigated. The matrix of boric acid substituted PGMA covalant affinity chromatographic were prepared using the PGMA copled with m aminophonyl boronic acid and the capacity of the banic acid of the matrix was up to 1.036mmol/g. |
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| Keywords: | glycidyl methacrylate ethylene dimethacrylate m aminophonyl boronic acid covalant affinity chromatography |
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