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| 间三氟甲基苯甲酸甲酯的合成 | |
| 引用本文： | 王凯泉,赵红英,陈静华,杜晓华. 间三氟甲基苯甲酸甲酯的合成[J]. 浙江化工, 2011, 42(5): 1-5 |
| 作者姓名： | 王凯泉 赵红英 陈静华 杜晓华 |
| 作者单位： | 1. 浙江巍华化工有限公司,浙江金华322109;浙江工业大学化材学院,浙江杭州310014 2. 浙江巍华化工有限公司,浙江金华,322109 3. 浙江工业大学化材学院,浙江杭州,310014 |
| 摘 要： | 以间甲基苯甲酰氯为起始原料,经侧链氯化反应、氟化反应和酯化反应合成了间三氟甲基苯甲酸甲酯。主要解决了氯化光源、氟化催化剂和酯化缚酸剂等关键技术,为工业化生产提供了可行的工艺条件。 |
| 关 键 词： | 间三氟甲基苯甲酸甲酯 间甲基苯甲酰氯 光氯化反应 氟化反应 酯化反应 |
Synthesis of Methyl m-Trifluoromethylbenzoate |
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| WANG Kai-quan,ZHAO Hong-ying,CHEN Jing-hua,DU Xiao-hua. Synthesis of Methyl m-Trifluoromethylbenzoate[J]. Zhejiang Chemical Industry, 2011, 42(5): 1-5 | |
| Authors: | WANG Kai-quan ZHAO Hong-ying CHEN Jing-hua DU Xiao-hua |
| Affiliation: | WANG Kai-quan1,2,ZHAO Hong-ying1,CHEN Jing-hua1,DU Xiao-hua2(1.Zhejiang Weihua Chemical Co.,Ltd.,Jinhua 322109,China,2.College of Chemical Engineering and Material Science,Zhejiang University of Technology,Hangzhou 310014,China) |
| Abstract: | Methyl m-trifluoromethylbenzoate is synthesized using m-methyl benzoyl chloride as a starting material,comprising 3 steps of side-chain chlorination,fluorination and esterification.The key techniques are resolved such as a special light source of chlorination,the catalyst of fluorination and the deacid regent of esterification.The optimized process conditions are obtained which suitable for the industrial-scale manufacture of the titled compound. |
| Keywords: | methy m-trifluoromethylbenzoate m-methylbenzoylchloride light chlorination fluorination esterification |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
