| 抗癌药物FT-207脂肪乳剂物理性质的研究 |
| |
| 引用本文： | 韩继洪,苏德森.抗癌药物FT-207脂肪乳剂物理性质的研究[J].沈阳药科大学学报,1991(1). |
| |
| 作者姓名： | 韩继洪 苏德森 |
| |
| 作者单位： | 沈阳药学院物理药学研究室，沈阳药学院物理药学研究室 黑龙江省中医学院中药系 |
| |
| 基金项目： | 中关村地区联合分析测试中心基金 |
| |
| 摘 要： | 本文对抗癌药物FT-207脂肪乳剂的制备及物理性质进行了研究。建立了乳剂物理稳定性新的评价方法。考查了乳化剂浓度、HLB值、FT-207浓度对乳剂稳定性的影响。测定了乳剂的粒度分布及乳剂的电位等物理性质。研究得到精制豆油乳化所需最佳HLB值为15.4,乳剂中分散液滴的平均粒径为1.0μm.
|
| 关 键 词： | FT-207 物理性质 离心分光法 |
STUDIES ON THE PHYSICAL PROPERTIES OF AN ANTICANCER DRUG FT-207 FAT EMULSION |
| |
| Han Jihong Su Desen Research.STUDIES ON THE PHYSICAL PROPERTIES OF AN ANTICANCER DRUG FT-207 FAT EMULSION[J].Journal of Shenyang Pharmaceutical University,1991(1). |
| |
| Authors: | Han Jihong Su Desen Research |
| |
| Affiliation: | Han Jihong Su Desen Research Department of Physical Pharmacy Shenyang College of Pharmacy |
| |
| Abstract: | In this paper studies on the preparation and physical properties of FT-207 fat emulsion are reported.A new method of centrifugal-spectrometry has been set up for measuring the stability of the fat emulsion. The effects of emulsifier concentration, HLB value and FT-207 concentration have been studied. Particle size distribution and Zeta potential of FT-207 fat emulsion have been determined. It has been found that the optimum HLB value for the emulsification of purified soybean oil in this system is 15.4. The mean diameter of oil droplets in the final product is 1.0μm. |
| |
| Keywords: | FT-207 Physical properties Centrifugal-spectrometry |
| 本文献已被 CNKI 等数据库收录！ |
