| 乳头瘤病毒及巨细胞病毒在宫颈癌组织中的协同作用 |
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| 引用本文： | 蔡红兵,陈惠祯,张洪平,舒梅芝. 乳头瘤病毒及巨细胞病毒在宫颈癌组织中的协同作用[J]. 武汉大学学报(医学版), 1995, 0(2) |
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| 作者姓名： | 蔡红兵 陈惠祯 张洪平 舒梅芝 |
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| 作者单位： | 武汉附二医院肿瘤科 |
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| 摘 要： | 应用ＤＮＡ－ＤＮＡ斑点杂交技术，对６４例宫颈标本（包括正常宫颈２６例，重度宫颈糜烂１７例，宫颈癌２１例）分别检测ＨＰＶ－１６ＤＮＡ及ＨＣＭＶＤＮＡ。结果发现正常宫颈、宫颈糜烂及宫颈癌组织中ＨＰＶ１６ＤＮＡ的检出率分别为２３．０８％、６４．７１％、７１．４３％。而ＨＣＭＶＤＮＡ的检出率则依次为３．８５％、２３．５４％、及４２．８６％，两者检出率呈直线相关（ｒ＝０．９２３）。因此，推测ＨＣＭＶ很可能与ＨＰＶ１６协同作用导致宫颈癌的发生。
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| 关 键 词： | 子宫颈肿瘤／病因学，乳头瘤病毒，巨细胞病毒 |
The Synergistic Effect of HPV and HCMV on the Occurence of Cervical Carcinoma |
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| Cai Hongbing,Chen Huizhen,Zhang Hongping,et al. The Synergistic Effect of HPV and HCMV on the Occurence of Cervical Carcinoma[J]. Medical Journal of Wuhan University, 1995, 0(2) |
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| Authors: | Cai Hongbing Chen Huizhen Zhang Hongping et al |
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| Abstract: | The dot-blot hydrization technique was employed to examine 64 cervical specimens(26 normal,17 serious erosion and 21 cerviacal cancer) for their HPV16 DNA and HCMV DNA,In these three groups the rates of HPV16 DNA were 23.08%,64.71% and 71.43% respectively and those of HCMV DNA were 3.85%,23.54% and 42.86% respectively.These two kinds of rate were in linear correlation(r=0.923).Therefore it is suspected that HCMV and HPV16 can lead in coorperation to cervical carcinoma. |
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| Keywords: | cervix neoplasms/ET papillomaviruses cytomegaloviruses |
| 本文献已被 CNKI 等数据库收录！ |
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