新发2型糖尿病患者早期胰岛素强化治疗临床疗效分析

目的：评价新发2型糖尿病患者早期胰岛素强化治疗的效果。方法：对28例新发2型糖尿病患进行早期胰岛素强化治疗。结果：空腹血糖（FPG）、餐后2h血糖（2hPG）、糖化血红蛋白（HbAlc）水平均显著下降（P〈0．01），而空腹C肽水平增高（P〈0．05），餐后2hC肽水SF（2hCP）明显升高（P〈0．01）。结论：早期胰岛素强化治疗能尽快解除高糖毒性，胰岛B细胞功能显著恢复，减轻糖毒性。

Clinical analysis of the new type 2 diabetes,intensive insulin therapy patients with

Objective： To evaluate a new type 2 diabetic patients intensive insulin therapy results. Methods： 28 patients with newly diagnosed type 2 diabetic patients for early intensive insulin therapy. Results： The fasting plasma glucose （FPG）, postprandial 2 h plasma glucose （2 h PG）, glycosylated hemoglobin （HbAlc） of water on average significantly decreased （P〈0.01）, while the fasting C-peptide levels increased（P〈0.05）, postprandial 2 h C-peptide level（2 h CP） was significantly higher then before（P〈0.01）. Conclusion： Early intensive insulin therapy can be lifted as soon as possible toxicity of high glucose, significantly restored pancreatic islet B-cell function,reducing sugar toxicity.