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牛黄系列药材化学成分比较及其药理作用研究概况
引用本文:邹秦文,石岩,魏锋,林瑞超,马双成.牛黄系列药材化学成分比较及其药理作用研究概况[J].中国药事,2014(6):646-650.
作者姓名:邹秦文  石岩  魏锋  林瑞超  马双成
作者单位:[1]北京联馨药业有限公司,北京102628 [2]沈阳药科大学中药学院 ,北京102628 [3]中国食品药品检定研究院 ,北京102628 [4]北京中医药大学中药学院,北京102628
摘    要:目的探讨牛黄系列药材化学成分及其药理作用的研究概况。方法检索近几年有关牛黄系列药材化学成分及其药理作用的研究资料。结果与结论牛黄系列药材即天然牛黄、培植牛黄、体外培育牛黄与人工牛黄的化学成分主要为胆红素与胆汁酸类,其在中枢神经系统、心血管及血液循环系统、消化系统、呼吸系统及免疫系统等方面具有解热镇痛、降压、抗炎、抗氧化、清除自由基、提高免疫力等作用。

关 键 词:牛黄  替代品  培植牛黄  体外培育牛黄  人工牛黄  化学成分  药理作用

Study on Chemical Composition and Pharmacological Effects of Bovis Calculus Medicinal Materials
Zou Qinwen,Shi Yan,Wei Feng,Lin Ruichao,Ma Shuangcheng.Study on Chemical Composition and Pharmacological Effects of Bovis Calculus Medicinal Materials[J].Chinese Pharmaceutical Affairs,2014(6):646-650.
Authors:Zou Qinwen  Shi Yan  Wei Feng  Lin Ruichao  Ma Shuangcheng
Affiliation:1. Beijing Lianxin Pharmaceutical Co. , Ltd, Beijing 102628; 2.School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University; 3 National Institutes for Food and Drug Control; 4 School of Chinese Materia Medica, Beijing University of Chinese Medicine)
Abstract:Objective To discuss the research progress in the chemical composition and pharmacological effects of bezoar medicinal materials. Methods Intensive search was performed for studies on the chemical composition and pharmacological effects of bezoar medicinal materials in the past few years. Results and Conclusion The main chemical components of bezoar medicinal materials such as natural bezoar, the cultured calculus bovis, in vitro cultured bezoar and artificial bezoar were bilirubin and bile acids, which had the effects of antipyretic and analgesic, depressurization, antiinflammatory, antioxidant, scavenging free radical and enhancing immunity in the CNS, cardiovascular and circulatory system, digestive system, respiratory system and the immune system.
Keywords:bovis calculus  succedaneums  cultivated bezoar  bovis calculus sativus  bovis calculus artifactus  chemical composition  pharmacologic action
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