| 老年高血压患者血压昼夜节律特点及药物干预的研究 |
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| 引用本文： | 梁积英,潘文晶,莫永秀,史文,杨立新,苏卫红,李维. 老年高血压患者血压昼夜节律特点及药物干预的研究[J]. 内科, 2009, 4(2): 191-193 |
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| 作者姓名： | 梁积英 潘文晶 莫永秀 史文 杨立新 苏卫红 李维 |
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| 作者单位： | 广西壮族自治区江滨医院心内科,南宁市,530021 |
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| 摘 要： | 目的研究老年高血压患者24h动态血压昼夜节律特点以及培哚普利干预的疗效。方法对60例老年高血压患者（观察组）和100例非老年高血压患者（对照组）进行动态血压监测（ABPM）；观察组患者给予口服培哚普利，于服药前后及检测24h动态血压（ABPM）、血脂、血糖、肝肾功能等。结果观察组患者昼夜节律性和全天及昼间舒张压低于对照组（P〈0．05）。夜间收缩压和脉压差均高于对照组（P〈0．001）。观察组口服培哚普利4周后，24h、白昼、和夜间血压均值均比治疗前明显下降（P〈0．01），夜间血压比白昼血压均值下降明显（P〈0．01）。结论老年高血压患者血压昼夜节律降低、动脉压差增大，白天舒张压降低、夜间收缩压增高、脉压差增大是老年高血压病血压昼夜节律特点。培哚普利能24h缓慢降低老年高血压患者血压尤其夜间收缩压，改善非杓型血压昼夜节律。
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| 关 键 词： | 高血压 老年人 动态血压监测 药物干预 |
Study on the circadian rhythm and drug intervention in elderly hypertension patients |
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| LIANG Ji-ying,PAN Wen-jing,MO Yong-xiu,SHI Wen,YANG Li-xin,SU Hong-wei,LI Wei. Study on the circadian rhythm and drug intervention in elderly hypertension patients[J]. Internal Medicine of China, 2009, 4(2): 191-193 |
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| Authors: | LIANG Ji-ying PAN Wen-jing MO Yong-xiu SHI Wen YANG Li-xin SU Hong-wei LI Wei |
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| Affiliation: | Department of Cardiovascular;Jiangbin Hospital of Guangxi Zhuang Autonomous Region;Nanning 530021;China |
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| Abstract: | Objective To investigate the 24 hours circadian rhythm of ambulatory blood pressure trend and the Perindoprill effect in elderly hypertension patients.Methods Ambulatory blood pressure monitoring(ABPM) was performed on 60 elderly hypertension patients(observed group) and 100 non-aged elderly hypertension patients(control group),the patients of observed group were tested blood-lipoids,blood-sugar,liver function,renal function and 24 hours ABPM before and after having Perindoprill.Results The circadian rhythm... |
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| Keywords: | Hypertension The elderly Ambulatory blood pressure monitoring Drug intervention |
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