| 不同剂量瑞舒伐他汀对老年缺血性脑卒中患者血脂的影响 |
| |
| 引用本文： | 何文绮. 不同剂量瑞舒伐他汀对老年缺血性脑卒中患者血脂的影响[J]. 中国医药指南, 2014, 0(31): 53-53 |
| |
| 作者姓名： | 何文绮 |
| |
| 作者单位： | 上海交通大学医学院附属瑞金医院卢湾分院神经科,上海200020 |
| |
| 摘 要： | 目的观察不同剂量瑞舒伐他汀钙对老年缺血性脑卒中患者血脂的影响。方法随机将50例血脂异常的老年缺血性脑卒中患者分为低剂量瑞舒伐他汀钙治疗组(5mg)和高剂量瑞舒伐他汀钙治疗组(10mg),每组25例,分别于治疗前、治疗后8周观察血脂水平变化。结果治疗8周后,二组患者总胆固醇(TC)、低密度脂蛋白(LDL-C)和三酰甘油(TG)水平均降低(P<0.01),高密度脂蛋白(HDL-C)升高(P<0.01),高剂量治疗组均优于低剂量治疗组(P<0.05)。结论不同剂量瑞舒伐他汀钙(5、10 mg)都能有效改善老年缺血性卒中患者血脂水平。
|
| 关 键 词： | 缺血性脑卒中 瑞舒伐他汀钙 血脂 |
Effect of Different doses of Rosuvastatin Calcium on Blood-fat in Elderly Patients with Cerebral Ischemic Stroke |
| |
| HE Wen-qi. Effect of Different doses of Rosuvastatin Calcium on Blood-fat in Elderly Patients with Cerebral Ischemic Stroke[J]. Guide of China Medicine, 2014, 0(31): 53-53 |
| |
| Authors: | HE Wen-qi |
| |
| Affiliation: | HE Wen-qi (Department of Neurology, Affiliated Ruijin Hospital Branch of Luwan, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China) |
| |
| Abstract: | Objective To observe the effect of different doses of rosuvastatin calcium on blood-fat in elderly patients with cerebral ischemic stroke. Methods Fifty elderly patients with dyslipidemia were randomly divided into low dose trial group （rosuvastatin calcium 5 mg/d） and high dose trial group （rosuvastatin calcium 10 mg/d）, 25 cases patients in each group. Blood lipid was tested before and after 8 weeks respectively. Results 8 weeks after treatment, the two groups of total cholesterol （TC）, low density lipoprotein（LDL-C）, triglycerides（TG） levels were reduced（P〈0.01）, high density lipoprotein cholesterol（HDL-C） were raised（P〈0.01）. High dose treatment group compared with low dose treatment group blood-fat change was more obvious（P〈0.05）. Conclusions Different doses of rosuvastatin calcium（5, 10 mg） can effectively improve blood lipid level in elderly patients with cerebral ischemic stroke. |
| |
| Keywords: | Ischemic stroke Rosuvastatin calcium Blood-fat |
| 本文献已被 维普 等数据库收录！ |
|
