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Selective Depletion of the Allo-Antigen Specific T Cells by Fas/FasL Pathway by Cytokine IFN-γ and IL-2
引用本文:肖娟,邹萍,刘忠文,刘凌波,胡中波. Selective Depletion of the Allo-Antigen Specific T Cells by Fas/FasL Pathway by Cytokine IFN-γ and IL-2[J]. 华中科技大学学报(医学英德文版), 2003, 23(4)
作者姓名:肖娟  邹萍  刘忠文  刘凌波  胡中波
作者单位:The Institute of Hematology,The Institute of Hematology,The Institute of Hematology,The Institute of Hematology,The Institute of Hematology Xiehe Hospital,Tongji Medical College Huazhong University of Science & Technology,Wuhan,430022,Xiehe Hospital,Tongji Medical College Huazhong University of Science & Technology,Wuhan,430022,Xiehe Hospital,Tongji Medical College Huazhong University of Science & Technology,Wuhan,430022,Xiehe Hospital,Tongji Medical College Huazhong University of Science & Technology,Wuhan,430022,Xiehe Hospital,Tongji Medical College Huazhong University of Science & Technology,Wuhan,430022
基金项目:hisprojectwassupportedbythegrantfromNationalNaturalScienceFoundationofChina (No .39770 76 7)
摘    要:Severegraft versus hostdisease (GVHD)isthemajorcauseoffailureofallogeneichematopoieticstemcelltransplantation (allo HSCT) .Thedonormatu rateTlymphocytesareactivatedwhentheyrecognizeallo histocompatibilityantigenofrecipients ,anddi rectlyswitchongraft versus hostreactionandcausetargettissueinjury[1] .DepletionofTcellsingraftorinhibitionoftheirfunctioncoulddeceleratetheoccur renceanddevelopmentofGVHD[2 ] .However ,Tcellsareabletoresistinfection ,killtumorcellsandsecretecytokinessuchasIL 3…


Selective Depletion of the Allo-Antigen Specific T Cells by Fas/FasL Pathway by Cytokine IFN-γ and IL-2
XIAO Juan,ZOU Ping,LIU Zhongwen,LIU Lingbo,HU Zhongbo The Institute of Hematology,Xiehe Hospital,Tongji Medical College Huazhong University of Science , Technology,Wuhan. Selective Depletion of the Allo-Antigen Specific T Cells by Fas/FasL Pathway by Cytokine IFN-γ and IL-2[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 2003, 23(4)
Authors:XIAO Juan  ZOU Ping  LIU Zhongwen  LIU Lingbo  HU Zhongbo The Institute of Hematology  Xiehe Hospital  Tongji Medical College Huazhong University of Science & Technology  Wuhan
Affiliation:XIAO Juan,ZOU Ping,LIU Zhongwen,LIU Lingbo,HU Zhongbo The Institute of Hematology,Xiehe Hospital,Tongji Medical College Huazhong University of Science & Technology,Wuhan,430022
Abstract:
Keywords:Fas ligand  CD34 + cells  T lymphocytes  apoptosis  graft versus host disease  cytokine
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