三七治疗肾脏病的药理与临床研究进展

三七具有多种生物学活性。三七可通过对肾小管上皮细胞及肾成纤维细胞的作用延缓肾间质纤维化的进展。其药理作用还包括调节免疫、影响炎性因子表达、清除氧自由基、钙拮抗作用、影响物质代谢和改善微循环等。三七在临床上应用于慢性肾小球肾炎、肾病综合征、糖尿病肾病及慢性肾衰竭等各种肾脏疾病的治疗,取得了良好的疗效。对三七的药理和临床研究的进一步深入,有望为肾脏疾病的防治开辟的途径。

Progress of Panax notoginseng in Pharmacological and Clinical Research for Nephropathy

Panax notoginseng hss various biological functions. It may prevent the progression of renal interstitial fibrosis through the effect on renal tubular epithelial cells and kidney fibroblnsts. Its pharmacological mechanism also includes immunoregulatien;influence on the expressien of inflammatory factors ; elimination of oxygen free radicals;inhibition of caleium uptske; influence on substance metsbolism, improvement of blood microcirculation and so on. Panax notoginseng was applied in clinic to treat kidney diseases such as chronic glomerulonephritis, nephrotic syndrome,diahetic nephropathy,ehronic renal failure, in which it got a significant curative effect. The further study in the pharmacological and clinical research of Panax notoginceng would provide a new way of prevention and treatment for kidney diseases.