魔鬼爪化学成分的研究

 目的研究魔鬼爪中的化学成分。方法运用各种色谱方法进行化学成分的分离纯化,用理化方法解析其化学结构。结果从该植物块茎中分得9个化合物,其中1～5为苯乙醇苷类化合物,6为三萜皂苷,结构分别被鉴定为martynoside(1),6-acetylacteoside(2),β-(3′,4′-dihydroxyphenyl)ethyl-O-α-L-rhamnopyranosyl(1→3)-β-D-glucopyranoside(3),acteoside(4)+isocteoside(5),7α,23-dihydroxytormenticacidesterglucoside(6),阿魏酸乙酯(7),二十五酸(8)及β-胡萝卜苷(9)。结论化合物1,6,7,8均为从该植物中首次分离得到。

Study on Chemical Constituents in Tuber of Harpagophytum procumbens D.C.

OBJECTIVE To investigate chemical components in the tuber of Harpagophytum procumbens D.C. METHODS The chemical components were isolated by column chromatography methods,and the structures were elucidated by spectral evidence.RESULTS Nine compounds were isolated.Compound 1～5 were phenylpropanoid glycosides and 6 was a triterpenoid saponin,then each was identified as martynoside(1),6-acetyl acteoside(2),β-(3′,4′-dihydroxyphenyl)ethyl-O-α-L-rhamnopyranosyl(1→3)-β-D-glucopyranoside(3),acteoside (4)+ isocteoside(5),7α,23-dihydroxytormentic acid ester glucoside(6),ethyl ferulate(7),pentacosanoic acid(8) and β-daucosterol(9),respectively.CONCLUSION Compound 1,6,7 and 8 are isolated from this plant for the first time.