| 噬菌体展示技术及其在感染性疾病中的应用 |
| |
| 引用本文： | 冯烨,涂长春.噬菌体展示技术及其在感染性疾病中的应用[J].粉末涂料与涂装,2009,22(8). |
| |
| 作者姓名： | 冯烨 涂长春 |
| |
| 作者单位： | 军事医学科学院军事兽医研究所,长春,130062 |
| |
| 摘 要： | 感染性疾病是病原体与宿主相互作用的结果。了解病原体与宿主相互作用的分子基础,对于感染性疾病的预防和控制尤为重要。噬菌体展示技术不仅广泛应用于抗原表位作图和抗体工程技术,而且还可用于研究蛋白质与配体的相互作用,以揭示感染过程中蛋白与配体的相互作用机制。本文仅就噬菌体展示技术及其在感染性疾病中的应用作一综述。
|
| 关 键 词： | 噬菌体展示技术 感染性疾病 |
Phage Display and Its Application to Infectious Diseases |
| |
| FENG Ye,TU Chang-chun.Phage Display and Its Application to Infectious Diseases[J].Chinese Journal of Biologicals,2009,22(8). |
| |
| Authors: | FENG Ye TU Chang-chun |
| |
| Abstract: | Microbial infections are dependent on the panoply of interactions between pathogen and host.Identifying the molecular basis of such interactions is necessary to understand and control infection.Phage display is not only widely used in antigenic epitope mapping,antibody engineering,but also to identify peptide-ligand and protein-ligand interactions that are of importance in infection.Phage display and its application to infectious diseases are reviewed in this paper. |
| |
| Keywords: | Phage display Infectious diseases |
| 本文献已被 万方数据 等数据库收录！ |
|
