平阳霉素治疗小儿体表血管瘤1658例临床疗效观察与护理

目的平阳霉素瘤内注射治疗小儿体表血管瘤的临床疗效观察与护理配合。方法回顾分析我科1997年1月。2008年1月以平阳霉素注射治疗小儿体表血管瘤1658例的临床资料，分析其临床疗效及护理方法。结果经过6．12个月（平均10．83个月）随访，总有效率为97．09％，不同类型血管瘤总有效率，差异具有统计学意义，海绵状血管瘤疗效最好，依次为草莓状血管瘤，混合性血管瘤，葡萄酒色斑痣疗效最差。本组发生局部溃破54例，发热有418例，过敏性休克3例。结论平阳霉素治疗小儿体表血管瘤是一种简便、安全有效的方法，易为患者接受。注射前应告知患者相关注意事项，注射后应积极评估应用平阳霉素引起的不良反应并对症治疗，及早防治各项并发症的发生，以提高治疗效果。

The therapeutic effect and nursing of Pingyangrnyein in treatment of 1658 children patients with hemangioma of body surface

Objective The therapeutic effect and nursing of pingyangrnyein in treatment of bemangioma of children body suuface was evaluated. Methods The clinical data and nursing ways of 1658 children patients with bemangioma of body surface in which pingyangmyein was injected between January 1997 and January 2008 were analyzed retropectively. Comsummated the notify before injection to make sure the patients to go with.Results All 1658 patients were observed for 6- 12 months,averaged 10.83 months.The total effective rate was 97.09%. Compared with different type bemangioma, total effective rate and complete remission（CR） rate had significant difference（ X^2 = 203.12, P 〈 0.01 ）, and complete remission（CR） rate had significant difference（ X^2 = 287.97, P 〈 0.01 ）. The therapeutic effect of pingyangmyein in treatment of cavernous hemangioma was better than mixed bemangioma, strawbeny hemangioma and pertwine stain. The therapeutic effect of portwine stain was lower than other hemangioma. 54 patients caught necrotic partial ulcer of hemangioma（2.91% ）. The were 418 eases of fever. There were 3 cases of allergic shock. Conclusion lifts method is a simple,safe and effective therapy to hemangioma of children body surface.Nurses should tell the patients all notices about the therapeutic before injection. To make the therapeutic effect better, evaluating the untoward effect of pingyangmyein and making symptomatic treatment early is important.