新生儿脐炎病原菌分析及临床意义

目的:了解新生儿脐炎病原菌分布及药物敏感状况,以利临床医生合理选用抗生素。方法:128例新生儿脐炎患儿作脐分泌物及血液病原菌分离和药敏试验,并对药敏试验结果进行分析。结果:128例中共分离出病原菌120株。新生儿脐炎的病原菌主要为金黄色葡萄球菌、表皮葡萄球菌、大肠埃希氏菌、肺炎克雷伯菌。革兰氏阳性球菌对苯唑青霉素、原始霉素、褐霉素、万古霉素等敏感率较高,革兰氏阴性杆菌对亚胺硫霉素、头孢噻甲羧肟、头孢甲氧噻吩、丁胺卡那霉素等敏感率较高。结论:了解新生儿脐炎的细菌谱及药物敏感状况,可以指导临床医生合理使用抗生素。

Analysis of pathogenic bacteria of neonatal omphalitis and its clinical significance

Objective:To study the antibiotic susceptibility of pathogenic bacteria of neonatal omphalitis to offer reference for reasonable use of antibiotics.Methods:The isolates from navel secretion samples of 128 inpatients with neonatal omphalitis were analyzed by antibiotic susceptibility test.Results:A total of 120 bacterial isolates were collected. Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Klebsiella pneumoniae were the main microorganism. G+ cocci were susceptible to oxacillin, Pristinamycin, fuscomycin and vancomycin. G? bacilli were susceptible to imipenem, Ceftazidime, cefoxitin, Amikacin.Conclusion:The understanding of bacteria of neonatal omphalitis and its antibiotic susceptibility can instruct the reasonable application of antibiotic in clinicians.