| 聚丙烯酸钠对钛表面仿生生长磷灰石涂层的调制 |
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| 引用本文： | 段可,程俊秋,翁杰,张兴栋.聚丙烯酸钠对钛表面仿生生长磷灰石涂层的调制[J].化学研究与应用,2001,13(4):468-470. |
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| 作者姓名： | 段可 程俊秋 翁杰 张兴栋 |
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| 作者单位： | 四川大学生物医学材料工程研究中心, |
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| 摘 要： | 1 前言羟基磷灰石 (Ｃａ10 (ＯＨ) 2 (ＰＯ4 ) 6,ｈｙｄｒｏｘｙａｐａｔｉｔｅ ,ＨＡ)作为人体硬组织的主要无机成分具有良好的生物活性。钛表面等离子喷涂ＨＡ综合了钛的力学性能和ＨＡ的生物活性 ,得到了广泛应用1] 。但喷涂技术具有视线效应的缺点 ,同时涂层与基体界面的长期可靠性也是广泛关注的问题。为此发展的各种涂层方法中仿生化学法制备磷灰石涂层是极为活跃的前沿领域2 ] 之一。仿生法基于异相成核原理3 ] :将基体预先功能化后浸入磷酸钙过饱和溶液 ,在溶液过饱和度低于均相沉淀的条件下在基体表面发生磷灰石异相成核并自发…
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| 关 键 词： | 羟基磷灰石 钛 聚丙烯酸 生物矿化 仿生化学法 仿生生长 表面涂层 制备 |
| 文章编号： | 1004-1656(2001)04-0468-03 |
| 修稿时间： | 2001年4月4日 |
SODIUM POLYACRYLATE MODULATION OF APATITE COATING ON TITANIUM PREPARED BY BIOMIMETIC APPROACH |
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| DUAN Ke,CHENG Jun qiu,WENG Jie,ZHANG Xing dong.SODIUM POLYACRYLATE MODULATION OF APATITE COATING ON TITANIUM PREPARED BY BIOMIMETIC APPROACH[J].Chemical Research and Application,2001,13(4):468-470. |
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| Authors: | DUAN Ke CHENG Jun qiu WENG Jie ZHANG Xing dong |
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| Abstract: | Biomimetic apatite coating was prepared on chemically modified titanium surface by soaking in supersaturated solution.When sodium polyacrylate was introduced into the solution at 0.48mg/L,crystal size was significantly reduced,the crystal geometry shifted from flakes to spherilites and made the coating denser.Polyacrylatewas inhibited while also triggered growth of hydroxyapatite crystals.Polyacrylate mimicked the role of organic matrix modulation in biomineralization. |
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| Keywords: | apatite titanium biomimetics polyacrylic acid biomineralization |
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