| HPLC法测定双丹口服液中丹皮酚的含量 |
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| 引用本文： | 石瑞平,曹璐玮. HPLC法测定双丹口服液中丹皮酚的含量[J]. 齐鲁药事, 2008, 27(1): 21-22 |
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| 作者姓名： | 石瑞平 曹璐玮 |
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| 作者单位： | 临沂市药品检验所,山东,临沂,276001 |
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| 摘 要： | 目的建立高效液相色谱法测定双丹口服液中丹皮酚含量的方法。方法采用Zorbax SB-C18(4.6mm×250mm,5μm)色谱柱,甲醇-水(65∶35)为流动相,流速1.0mL.min-1,检测波长为274nm。结果丹皮酚线性范围为0.214~1.069μg,平均回收率为98.36%,RSD为0.36%。结论该方法简便、可靠、准确,可用于该制剂的质量控制。
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| 关 键 词： | 双丹口服液 丹皮酚 高效液相色谱法 |
| 文章编号： | 1672-7738（2008）01-0021-02 |
Determination of paeonol in Shuangdan Oral Liquid by HPLC |
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| SHI Rui-ping,CAO Lu-wei. Determination of paeonol in Shuangdan Oral Liquid by HPLC[J]. qilu pharmaceutical affairs, 2008, 27(1): 21-22 |
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| Authors: | SHI Rui-ping CAO Lu-wei |
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| Abstract: | OBJECTIVE To establish an HPLC method for determination of paeonol in Shuangdan Oral Liquid.METHODS A Zorbax SB-C18(4.6mm×250mm,5μm) column was used.The mobile phase was methanol-water(60∶35).The flow rate was 1.0mL·min-1.The detective wavelength was 274nm.RESULTS The linear range of paeonol was 0.214～1.069μg,and the average recovery rate was 98.36%,RSD = 0.36%.CONCLUSION The method was simple,reliable and accurate,it can be used to control the quality of preparation. |
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| Keywords: | Shuangdan Oral Liquid paeonol HPLC |
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