单眼先天性上睑下垂患儿图形视觉诱发电位分析

目的探讨单眼先天性上睑下垂患儿图形视觉诱发电位（P—VEP）的特点，评估P—VEP对上睑下垂患儿双眼视觉功能检测的意义。方法对53例2～4岁单眼先天性上睑下垂患儿进行P—VEP检查，比较双眼P—VEP的P100潜伏期及振幅是否存在差异。结果上睑下垂眼VEP P100波潜伏期较正常组延长（P〈0．01），振幅低于正常眼（P〈0．01）。轻度上睑下垂眼P—VEP P100波振幅与中度及重度相比，差异有统计学意义（P〈0．01），中度与重度相比差异无统计学意义，轻度上睑下垂眼P—VEP P100波潜伏期与中度相比差异无统计学意义，与重度比差异有统计学意义（P〈0．01），中度与重度比较差异有统计学意义（P〈0．05）。结论单眼先天性上睑下垂患者双眼P—VEP P100波振幅及潜伏期存在差异，根据患儿视觉发育程度进行手术时机选择的同时，应注意术后矫正弱视。

The analysis of visual evoked potential in patients with monocular congenital ptosis

Objective To investigate the visual evoked potential （P-VEP） feature in patients with monocular congenital ptosis. To evaluate the significance of P-VEP in binocular vision. Methods P-VEP response was recorded in 53 monocular congenital ptosis children who were 2-4 years old. Then compared the differences of latency period and waver of P100 wave. Results Compared with normal eye,the latency period of ptosis eyes was longer and the amplitude was lower（P 〈 0.01）.The differences of amplitude between mild ptosis eyes and midrange or severe ptosis eyes were significant （P 〈 0.01） while they were not significantly between midrange and severe group.The differences of latency period between mild ptosis eyes and midrange eyes were not significant while they were significantlly between midrange and severe group（P 〈 0.01,P 〈 0.05）. Conclusion Patients with monocular congenital ptosis edured differences response of P-VEP P100 in amplitude and latency period between two eyes.Attention should be focused on mblyopia after surgery.