| 超声编码激励在瞬时弹性成像检测中的应用 |
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| 引用本文： | 和晓念,林浩铭,刁现芬,孟德明,覃正笛,陈思平,陈昕. 超声编码激励在瞬时弹性成像检测中的应用[J]. 声学技术, 2017, 36(4): 340-345 |
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| 作者姓名： | 和晓念 林浩铭 刁现芬 孟德明 覃正笛 陈思平 陈昕 |
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| 作者单位： | 深圳大学医学院, 医学超声关键技术国家地方联合工程实验室, 广东省生物医学信息检测与超声成像重点实验室, 广东深圳 518060,深圳大学医学院, 医学超声关键技术国家地方联合工程实验室, 广东省生物医学信息检测与超声成像重点实验室, 广东深圳 518060,深圳大学医学院, 医学超声关键技术国家地方联合工程实验室, 广东省生物医学信息检测与超声成像重点实验室, 广东深圳 518060,桂林电子科技大学, 广西桂林, 541004,深圳大学医学院, 医学超声关键技术国家地方联合工程实验室, 广东省生物医学信息检测与超声成像重点实验室, 广东深圳 518060,深圳大学医学院, 医学超声关键技术国家地方联合工程实验室, 广东省生物医学信息检测与超声成像重点实验室, 广东深圳 518060,深圳大学医学院, 医学超声关键技术国家地方联合工程实验室, 广东省生物医学信息检测与超声成像重点实验室, 广东深圳 518060 |
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| 基金项目： | 国家自然科学基金资助项目（81471735，61427806，61201041）、国家科技支撑计划（2015BAI01B02）、广东省自然科学基金（2016A030310047）、深圳海外创新基金项目（KQC201105310020A） |
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| 摘 要： | 瞬时弹性(Transient Elastography,TE)成像广泛应用于肝硬化研究。然而,在临床应用中,对于肥胖病人,该方法很难实现对深度位置的瞬时剪切波进行检测。研究了将超声编码激励应用于瞬时弹性成像剪切波检测的可行性,选用7位巴克码进行编码检测研究。通过剪切波信噪比和检测穿透力两个指标对编码检测与传统短脉冲检测结果进行量化和对比。弹性仿体实验表明,编码检测可以提供比传统短脉冲检测更高的剪切波信噪比和检测深度。离体猪肝实验表明将编码激励应用于组织检测时同样可以实现高信噪比剪切波检测。这些结果表明编码检测应用于瞬时弹性成像检测是可行的,可以增加其检测深度。
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| 关 键 词： | 瞬时弹性成像 超声编码激励 剪切波信噪比 穿透力 |
| 收稿时间： | 2016-08-30 |
| 修稿时间： | 2016-10-22 |
Application of ultrasound coded excitation in transient elastography detection |
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| HE Xiao-nian,LIN Hao-ming,DIAO Xian-fen,MENG De-ming,QIN Zheng-di,CHEN Si-ping and CHEN Xin. Application of ultrasound coded excitation in transient elastography detection[J]. Technical Acoustics, 2017, 36(4): 340-345 |
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| Authors: | HE Xiao-nian LIN Hao-ming DIAO Xian-fen MENG De-ming QIN Zheng-di CHEN Si-ping CHEN Xin |
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| Affiliation: | School of Biomedical Engineering, Shenzhen University, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Shenzhen 518060, Guangdong, China,School of Biomedical Engineering, Shenzhen University, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Shenzhen 518060, Guangdong, China,School of Biomedical Engineering, Shenzhen University, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Shenzhen 518060, Guangdong, China,Guilin University of Electronic Technology, Guilin 541004, Guangxi, China,School of Biomedical Engineering, Shenzhen University, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Shenzhen 518060, Guangdong, China,School of Biomedical Engineering, Shenzhen University, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Shenzhen 518060, Guangdong, China and School of Biomedical Engineering, Shenzhen University, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Shenzhen 518060, Guangdong, China |
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| Abstract: | Transient elastography (TE) is well adapted for use in studying liver elasticity. However, in clinical application, it is challenging to detect the transient shear wave motion in a severe noise environment, such as within deep tissues and for obese patients. This paper, therefore, investigates the feasibility of implementing coded excitation in TE for shear wave detection. The 7 bit Barker code is used in this study. The performances of coded excitation for transient elastography are quantitatively compared in terms of shear wave SNR and the detection depth. Elastic phantom experiment shows that coded pulse outperform traditional short pulse by providing superior shear wave SNR and detection depth. Results from the in vitro liver experiment prove the feasibility of implementing the coding technique in tissue and shows that the coded pulses could provide higher shear wave SNR than the traditional short pulse. These promising results prove the feasibility of implementing coded excitation in TE application, to facilitate superior detection depth. |
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| Keywords: | transient elastography ultrasound coded excitation shear wave SNR penetration |
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