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桦褐孔菌子实体中三萜类化合物的研究进展
引用本文:王艳,苑宏博,董迎迎,李虹佳,赵宁,辛嘉英,张兰威. 桦褐孔菌子实体中三萜类化合物的研究进展[J]. 食品工业科技, 2022, 43(9): 416-422. DOI: 10.13386/j.issn1002-0306.2021040158
作者姓名:王艳  苑宏博  董迎迎  李虹佳  赵宁  辛嘉英  张兰威
作者单位:1.哈尔滨商业大学食品工程学院,黑龙江哈尔滨 1500762.中国科学院兰州化学物理研究所,羰基合成与选择氧化国家重点实验室,甘肃兰州 7300003.哈尔滨工业大学,化工学院食品科学与工程系,黑龙江哈尔滨 150076
基金项目:黑龙江省自然科学基金(LH2021C051);哈尔滨商业大学青年创新人才项目青年后备人才专项(2019CX33);黑龙江省“百千万”工程科技重大专项支撑行动计划(2021ZX12B07)的子课题(2021ZX12B07-2);中央支持地方高校改革发展资金人才培养支持计划项目(高水平人才)(304017)
摘    要:桦褐孔菌是一种具有多种生物活性的天然植物真菌资源,三萜类化合物是其主要功效成分,因三萜类化合物具有优良的抗癌、降血糖和抗氧化等功能特性,其相关研究开发近年来备受关注。本文主要从桦褐孔菌三萜类化合物的诱导发酵生产,子实体三萜类化合物的分离纯化、化学组成及结构解析、功能特性和应用开发等方面对其研究现状进行总结分析,其中,诱导发酵生产方面使用植物共生微生物提取物作为诱导剂效果最为显著,分离纯化技术根据目的不同各有优势,在进行化学组成及结构解析时更适合采用分离效能高的分离纯化技术如高效逆流色谱、高效液相色谱等,规模化应用则大孔树脂更具优势,基于以上分析对其今后的研究方向进行了展望,为后续开发研究和医药与食品行业应用提供了理论依据。

关 键 词:桦褐孔菌   子实体   三萜类化合物   抗癌   降血糖   抗氧化
收稿时间:2021-04-15

Analysis on Research Status of Triterpenoids in Sporophore of Inonotus obliquus
WANG Yan,YUAN Hongbo,DONG Yingying,LI Hongjia,ZHAO Ning,XIN Jiaying,ZHANG Lanwei. Analysis on Research Status of Triterpenoids in Sporophore of Inonotus obliquus[J]. Science and Technology of Food Industry, 2022, 43(9): 416-422. DOI: 10.13386/j.issn1002-0306.2021040158
Authors:WANG Yan  YUAN Hongbo  DONG Yingying  LI Hongjia  ZHAO Ning  XIN Jiaying  ZHANG Lanwei
Affiliation:1.College of Food Engineering, Harbin University of Commerce, Harbin 150076, China2.State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China3.College of Chemical and Engineering, Harbin Institute of Technology, Harbin 150076, China
Abstract:Inonotus obliquus is anatural plant fungal resource with a variety of biological activities. Triterpenoids are the main functional components. Because triterpenoids have excellent anticancer, hypoglycemic and antioxidant properties, the related research and development has attracted much attention in recent years. In this paper, the current research status of Inonotus obliquus triterpenoid compounds are summarized and analyzed from the aspects of induction fermentation production, separation and purification of sporophore triterpenoid compounds, chemical composition and structure analysis, functional characteristics and application development, among which the use of plant commensal microbial extracts as inducers in induction fermentation production is the most significant. The separation and purification techniques have respective advantages according to different purposes. The separation and purification technologies with high separation efficiency such as high-performance counter-current chromatography and high-performance liquid chromatography are more suitable for chemical composition and structure analysis, and macroporous resin has more advantages in large-scale application. Based on the above analysis, the future research direction is prospected, which provides a theoretical basis for subsequent development and research and application in that medicine and food industry.
Keywords:
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