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原发性肺癌化疗前后的血液流变指标观察
引用本文:赵中苏,李磊,高培松,粟奇志,刘翠霞,乔惠珑.原发性肺癌化疗前后的血液流变指标观察[J].中国血液流变学杂志,1992(2).
作者姓名:赵中苏  李磊  高培松  粟奇志  刘翠霞  乔惠珑
作者单位:新疆军区总医院胸内科 新疆乌鲁木齐830000 (赵中苏,李磊,高培松,刘翠霞),新疆医学院一附院药剂科 新疆乌鲁木齐830000(粟奇志),新疆军区总医院胸内科 新疆乌鲁木齐830000(乔惠珑)
摘    要:本文对30例肺癌患者的血液流变指标进行了测定,并对其中15例化疗前后进行了比较。肺癌患者的血液流变指标中,血浆纤维蛋白原(Fib)、血沉、血沉方程K值和JB值显著升高。肺癌病人化疗后红细胞压积明显降低,血浆纤维全白原随病情缓解有所降低,血沉有所增加,各种综合因素的改善,使JB值显著降低。化疗可以直接杀伤肿瘤细胞,还可以改善血液流变性质使病情缓解。血液流变指标的测定可作为监测肺疾患者病情演变和判断疗效与预后的一个辅助指标。

关 键 词:肺癌  化学治疗  血液流变学

HEMORHEOLOGICAL OBSERVATION OF PRIMARY LUNG CANCER BEFORE AND AFTER CHEMOTHERAPY
Zhao Zhongsu,et al.HEMORHEOLOGICAL OBSERVATION OF PRIMARY LUNG CANCER BEFORE AND AFTER CHEMOTHERAPY[J].Chinese Journal of Hemorheology,1992(2).
Authors:Zhao Zhongsu  
Abstract:Hemorheological indexes of 30 cases of lung cancer were detected, of which 15 cases were com- pared before and after chemotherpy. There's a marked increase of fibrinogen, blood sedimentation, value K and JB of the edimentation in hemorheological equation. Postchemotherapy, hematocrity de- creased markably in patients with lung cancer. Along with the relief of the case, there's a decrease in fibrinogen and blood sedimentation. Improvement of composite factor made JB value decrease signifi- cantly. Chemotherapy can kill tumor cells directly, improve the property of hemorheology and thus lessen the seriousness of the case. The assay of hemorheological indexes may be employed to detect the development in patients with lung cancer. It is also a helping index for effectiveness of treatment and prognosis.
Keywords:lung cancer chemotherapy hemorheology
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