高龄女性冠心病患者冠脉造影特点及经皮冠状动脉介入治疗的临床观察

目的 分析高龄(≥80岁)女性冠心病(CHD)患者冠脉造影(CAG)特点及冠脉介入治疗的临床疗效.方法 比较162例高龄女性冠心病患者(A组)与271例高龄男性CHD患者(B组)临床和冠脉造影的特点及介入治疗的疗效和主要不良心脑血管事件(MACCE)发生率.结果 与B组比较,A组患者冠脉血管细小、病变复杂且严重.远期随访结果:A组血运重建率明显高于B组[15.1%(21/139)vs.6.5%(15/230)](P<0.05);A组MACCE发生率略高于B组[12.2%(17/139)vs.8.3%(19/230)](P>0.05).结论 与高龄男性冠心病患者相比,高龄女性CHD患者的冠脉细小、病变复杂,行介入治疗同样安全有效,血运重建率高,但MACCE发生率高.

Features of coronary angiography and clinical outcomes of percutaneous coronary intervention in aged females with coronary artery disease

Objective To analyze the features of coronary angiography (CAG) and clinical outcomes of percutaneous coronary intervention (PCI) in aged ( ≥ 80 years of age) females with coronary artery disease (CHD). Methods The features of CAG, clinical outcomes of PCI and occurrence of main adverse cardiocerebral events( MACCE) in 162 females with CHD( group A) were compared with those in 271 aged CHD males(group B). Results Compared with group B,the diseased coronary artery in group A was smaller with more serious and complicated. Long-term follow-up showed that vescular remodeling rate was higher in group A than that in group B [15. 1%(21/139) vs. 6. 5%(15/230)](P<0. 05) and occurrence rate of MACCE was slightly more in group A than that in group B [12. 2%(17/139) vs. 8. 3%(19/230)](P>0. 05). Conclusion Compared with aged males with CHD, the diseased coronary artery of aged CHD females was smaller with more serious and complicated lesions. Stent implantation for the aged CHD females is as effective as that for the aged CHD mailes with higher vescular remodeling rate and more occurrence of MACCE.