幽门螺杆菌感染与6岁以上儿童再发性腹痛的关系及其治疗

目的探讨幽门螺杆菌(Hp)感染与6岁以上儿童再发性腹痛(RAP)的关系及Hp感染的相关性治疗。方法选择2007年3月-2009年2月在本院就诊的符合RAP诊断的6岁以上患儿180例,同期选择无RAP的健康儿童30例作为健康对照组,采用14C-尿素呼气试验(14C-UBT)检测Hp感染情况;对Hp阳性的RAP患儿予根除Hp治疗,观察腹痛缓解率、Hp转阴率。结果RAP组Hp感染阳性率为58.33%,较健康对照组Hp感染率(20.00%)显著升高(P<0.01)。RAP组的3个年龄组中,12～14岁组Hp阳性率(69.35%)显著高于6～8岁组(46.51%)和9～11岁组(56.00%)(Pa<0.05)。RAP组中男、女的Hp阳性率分别为55.26%、60.58%,二者比较差异无统计学意义(P>0.05)。有无不良饮食习惯,家族中有无胃病史者Hp感染阳性率分别是45.56%、12.78%,49.44%、8.89%,二组比较差异均有统计学意义(Pa<0.01)。三联疗法根除Hp采用与否腹痛的缓解率、Hp转阴率分别为92.39%、15.38%,89.13%、7.69%,二组比较差异有统计学意义(Pa<0.01)。结...

Correlation between Helicobacter Pylori Infection and Recurrent Abdominal Pain in Children Over 6 Years Old and Its Treatment

Objective To explore the correlation between Helicobacter pylori (Hp) infection and recurrent abdominal pain (RAP) in children over 6 years old and its relative treatment.Me-thods One hundred and eighty children over 6 years old with the diagnosis of RAP from Mar.2007 to Feb.2009 were selected,30 healthy children without RAP were taken as the healthy control group at the same period.14C-urea breath test (14C-UBT) was used to detect whether the patient was infected by Hp.The radical cure of Hp was given to t...