| 六味千骨巴布剂的稳定性考察 |
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| 引用本文： | 邬金迪,马妍妍,王琪,刘世萍,李业雨,郭美华. 六味千骨巴布剂的稳定性考察[J]. 中国药师, 2014, 0(5): 751-754 |
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| 作者姓名： | 邬金迪 马妍妍 王琪 刘世萍 李业雨 郭美华 |
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| 作者单位： | 哈尔滨医科大学附属第一医院药学部 哈尔滨 150001;哈尔滨医科大学附属第一医院药学部 哈尔滨 150001;哈尔滨医科大学附属第一医院药学部 哈尔滨 150001;哈尔滨医科大学附属第一医院药学部 哈尔滨 150001;哈尔滨医科大学附属第一医院药学部 哈尔滨 150001;哈尔滨医科大学附属第一医院药学部 哈尔滨 150001 |
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| 基金项目： | 黑龙江省中医药科研项目(ZHY12-Z155) |
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| 摘 要： | 考察六味千骨巴布剂的稳定性。方法：用HPLC法测定六味千骨巴布剂中柚皮苷的含量，并考察性状、鉴别、舍膏量、赋形性、黏附性、微生物限度等其他指标。结果：六味千骨巴布剂样品在加速试验及长期试验中，考察前后各项检查指标均无明显变化。结论：六味千骨巴布剂在室温条件下稳定性较好。本品的工艺及包装等设计合理，符合制剂稳定的要求。
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| 关 键 词： | 六味千骨巴布剂 稳定性 质量评价 高效液相色谱法 柚皮苷 |
| 收稿时间： | 2013-12-20 |
| 修稿时间： | 2014-01-15 |
Study on Stability of Liuwei Qiangu Cataplasms |
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| Wu Jindi,Ma Yanyan,Wang Qi,Liu Shiping,Li Yeyu and Guo Meihua. Study on Stability of Liuwei Qiangu Cataplasms[J]. China Pharmacist, 2014, 0(5): 751-754 |
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| Authors: | Wu Jindi Ma Yanyan Wang Qi Liu Shiping Li Yeyu Guo Meihua |
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| Affiliation: | Department of Pharmacy, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China;Department of Pharmacy, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China;Department of Pharmacy, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China;Department of Pharmacy, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China;Department of Pharmacy, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China;Department of Pharmacy, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China |
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| Abstract: | To investigate the stability of Liuwei Qiangu cataplasms. Methods： The active ingredient （naringin） in the samples was determined by HPLC. Meanwhile, the other indices including character, identification, ointment content, adhesion, mi- crobial limit and so on were detected as well. Results： The results of the accelerated test and long term test showed that Liuwei Qiangu cataplasms were stable. No significant change in each index was found before and after the tests. Conclusion： Liuwei Qiangu cata-plasms are stable at room temperature. The designs of preparation process and package are rational to keep the stability of the prepara- tion. |
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| Keywords: | Liuwei Qiangu cataplasms Stability HPLC Naringin |
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