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Association between lumican gene -1554 T/C polymorphism and high myopia in Asian population:a meta-analysis |
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| Authors: | Xuan Liao Xu-Bo Yang Meng Liao Chang-Jun Lan and Long-Qian Liu |
| Affiliation: | Department of Ophthalmology, Fuling Center Hospital of Chongqing City, Chongqing 408000, China;Department of Ophthalmology, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China;Department of Ophthalmology, Fuling Center Hospital of Chongqing City, Chongqing 408000, China;Department of Ophthalmology, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China |
| Abstract: | Uveitis is one of the most important causes of blindness worldwide. Its etiology and pathogenesis are complicated and have not been well understood. The treatment for uveitis is predominantly based on steroids and immunosuppressants. However, systemic side effects limit their clinical application. With the advancement of molecular biology, some intravitreal implants and biologic agents have been used for the treatment of uveitis. Additionally, novel techniques such as gene therapy and RNA interference are being studied for using as uveitis therapy. This paper reviews recent advances in uveitis treatment. |
| Keywords: | uveitis intravitreal implants biologic agents gene therapy RNA interference |
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