尖锐湿疣患者人乳头瘤病毒的检测与分型

目的:了解尖锐湿疣(CA)患者人乳头瘤病毒(HPV)的型别分布。方法:采用实时荧光定量聚合酶链反应法对CA患者病变部位疣体或分泌物进行HPV DNA(高危型和低危型)检测。结果:110例CA患者中,HPV阳性检出率为100.00%。低危感染占64.55%,高危感染占14.55%,高低危复合感染占20.91%。不同性别和年龄患者HPV检出率差异均无统计学意义(P0.05)。结论:CA患者以低危型HPV感染为主,高危HPV感染有较高比例分布,提示应加强生殖器肿瘤的防治。

The typing and detecting of human papillomavirus in patients with condyloma acuminatum

Objective ：To investigate the type distribution of human papillomavirus （HPV） in patients with condyloma acuminatum （CA）. Methods：The HPV DNA （high-risk and low-risk type） of lesion and secretion of eondyloma aeuminatnm in CA patients were detected by fluorescent quantitative polymerase chain reaction. Results：The positive detection rates of HPV in 110 CA patients were 100%. Low-risk, high-risk and high and low-risk compound infection in all CA patients were 64. 55%, 14. 54% and 20.91% ,respectively. The detection rate differences of HPV in different gender and age had no statistical significance（ P 〉 0.05 ）. Conclusions：The low-risk HPV infection is mostly and high-risk HPV infection is relatively high in CA patients. It suggests that the prevention and treatment of genital tumor should be strengthened.